Comparison of Retinal Nerve Fiber Layer Thickness in Normal Eyes Using Time-Domain and Spectral-Domain Optical Coherence Tomography

Seibold, Leonard K.; Mandava, Naresh; Kahook, Malik Y.

doi:10.1016/j.ajo.2010.06.024

Cited by 95 publications

(108 citation statements)

References 20 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…The quantification of RNFL was also done using three SD-OCT (Spectralis, Cirrus and RTVue) and one TD-OCT (Stratus). Despite high correlation among these instruments, RNFL values were significantly different between the instruments [16].…”

Section: Background Workmentioning

confidence: 95%

See 1 more Smart Citation

Early Detection of Glaucoma Through Retinal Nerve Fiber Layer Analysis Using Fractal Dimension and Texture Feature

Lamani¹,

Manjunath²,

Mahesh³

et al. 2014

IJRET

View full text Add to dashboard Cite

show abstract

Section: Background Workmentioning

confidence: 95%

“…Fractal analysis is potentially suitable for an objective quantification of spatial heterogeneity because it is believed to be effective in characterizing complex systems that are hard to describe using conventional Euclidean geometry. Fractal dimension is a parameter that can be determined solely by the image intensity [16].…”

Section: Fractal Dimensionmentioning

confidence: 99%

Early Detection of Glaucoma Through Retinal Nerve Fiber Layer Analysis Using Fractal Dimension and Texture Feature

Lamani¹,

Manjunath²,

Mahesh³

et al. 2014

IJRET

View full text Add to dashboard Cite

show abstract

“…8 Recent studies demonstrated that PRNFL measured by SD-OCT (Cirrus and Spectralis) was thinner compared with the corresponding TD-OCT measurements in normal and glaucomatous eyes. 11,12 A possible reason is the different segmentation algorithms used: SD-OCT aims to identify the bottom of the nerve fibre layer, whereas TD-OCT attempts to localise the top of the ganglion cell layer.…”

Section: Discussionmentioning

confidence: 99%

“…Previous studies showed variable results in correlation and agreement analyses among different OCT instruments, [11][12][13] and most published studies focused on normal and glaucomatous eyes.…”

Section: Introductionmentioning

confidence: 99%

Optic Disc and Macular Imaging in Blind Eyes from Non-glaucomatous Optic Neuropathy: A Study with Spectral-domain Optical Coherence Tomography

Hansapinyo

Cheng

Chan

et al. 2016

Neuro-Ophthalmology

View full text Add to dashboard Cite

The purpose of this study was to determine and compare the optic disc and macular thickness measurements using two spectral-domain optical coherence tomography (SD-OCT) instruments in long-standing blind eyes diagnosed with non-glaucomatous optic neuropathies (NGON). A prospective observational case-series design was used. Twelve eyes from 12 NGON patients with no light perception for at least 6 months underwent optic disc and macular imaging with Cirrus HD-OCT and Spectralis OCT. The correlation between the peripapillary retinal nerve fibre layer (PRNFL) and macular ganglion cell layer and inner plexiform layer (GCL+IPL) thicknesses, and between the duration of no light perception (NLP) and PRNFL/GCL+IPL thicknesses were determined using Spearman's correlation analysis. The mean average PRNFL thickness was 55.9 ± 4.8 µm for Cirrus HD-OCT, which was significantly thicker than that measured by Spectralis OCT (31.9 ± 7.4 µm; p < 0.001). The mean central macular thickness on Cirrus HD-OCT was normal, but there was global thinning at the other macular areas. The mean average GCL +IPL thickness on Cirrus HD-OCT was 51.8 ± 5.8 µm. There was a good correlation between average PRNFL thickness and GCL+IPL thickness (r = 0.830, p = 0.002); however, there was no significant correlation between the duration of NLP to the average PRNFL thickness (on either instruments) or GCL+IPL thickness on Cirrus HD-OCT (p > 0.7). These results show that there was residual PRNFL thickness in NGON eyes with NLP, which varied significantly between SD-OCT instruments. The values of the residual PRNFL and GCL+IPL thicknesses in blind eyes (the "floor" effect) may be useful for prognostic purposes for patients with partial optic atrophy. ARTICLE HISTORY

show abstract

“…Among the advantages of SD over TD-OCT are: reduction in motion artifacts, improvement in axial resolution and better reproducibility of RNFL measurements (8,9) . In fact, recent studies have shown that the se related, but distinct technologies are not interchangeable, with sig nificant differences in RNFL measurements between them (10,11) . There is still controversy whether SD improves diagnostic ability compa red to TD-OCT in glaucoma (12)(13)(14) .…”

Section: Introductionmentioning

confidence: 99%

Nerve fiber layer in glaucomatous hemifield loss: a case-control study with time- and spectral-domain optical coherence tomography

Reis¹,

Vidal²,

Kreuz³

et al. 2012

Arq. Bras. Oftalmol.

View full text Add to dashboard Cite

Purpose: To evaluate the retinal nerve fiber layer measurements with time-domain (TD) and spectral-domain (SD) optical coherence tomography (OCT), and to test the diagnostic ability of both technologies in glaucomatous patients with asymmetric visual hemifield loss. Methods: 36 patients with primary open-angle glaucoma with visual field loss in one hemifield (affected) and absent loss in the other (non-affected), and 36 age-matched healthy controls had the study eye imaged with Stratus-OCT (Carl Zeiss Meditec Inc., Dublin, California, USA) and 3 D OCT-1000 (Topcon, Tokyo, Japan). Peripapillary re tinal nerve fiber layer measurements and normative classification were recorded. Total deviation values were averaged in each hemifield (hemifield mean deviation) for each subject. Visual field and retinal nerve fiber layer "asymmetry indexes" were calculated as the ratio between affected versus non-affected hemifields and corresponding hemiretinas. Conclusions: Normal hemifields of glaucoma patients had thinner retinal nerve fiber layer than healthy eyes, as measured by TD and SD-OCT. Retinal nerve fiber layer measurements were thicker with TD than SD-OCT. SD-OCT detected abnormal retinal nerve fiber layer thickness more often than TD-OCT.

show abstract

Comparison of Retinal Nerve Fiber Layer Thickness in Normal Eyes Using Time-Domain and Spectral-Domain Optical Coherence Tomography

Cited by 95 publications

References 20 publications

Early Detection of Glaucoma Through Retinal Nerve Fiber Layer Analysis Using Fractal Dimension and Texture Feature

Early Detection of Glaucoma Through Retinal Nerve Fiber Layer Analysis Using Fractal Dimension and Texture Feature

Optic Disc and Macular Imaging in Blind Eyes from Non-glaucomatous Optic Neuropathy: A Study with Spectral-domain Optical Coherence Tomography

Nerve fiber layer in glaucomatous hemifield loss: a case-control study with time- and spectral-domain optical coherence tomography

Contact Info

Product

Resources

About