Comparison of resting energy expenditure in bronchopulmonary dysplasia to predicted equation

Abstract

Objective: Children with bronchopulmonary dysplasia (BPD) often suffer from growth failure because of disturbances in energy balance with an increase of resting energy expenditure (REE). Evaluation of REE is a useful tool for nutritional management. Indirect calorimetry is an elective method for measuring REE, but it is time consuming and requires rigorous procedure. The objective of this study was to test accuracy of prediction equation to evaluate REE in BPD children. Patients and methods: Fifty-two children aged 4-10 years with BPD (30 boys and 22 girls) and 30 healthy lean children (20 boys and 10 girls) were enrolled. In this study, indirect calorimetry was compared to four prediction equations (Schoffield-W, Schoffield-HW, Harris-Benedict and Food and Agriculture Organization equation) using Bland-Altman pair wise comparison. Results: The Harris-Benedict equation was the best equation to predict REE in children with BPD, and Schoffield-W was the best in healthy children. For the children with chronic lung disease of prematurity the Harris-Benedict equation showed the lowest mean predicted REEÀREE measured by indirect calorimetry difference (difference ¼ 15 kcal/day; limits of agreement À266 and 236 kcal/day; 95% confidence interval for the bias À207 to 177 kcal/day), and graphically, the best agreement. For the group of healthy children, it was the Schofield-W equation (À2.9 kcal/day; limits of agreement À275 and 269 kcal/day; 95% confidence interval for the bias À171 to 165 kcal/day), and graphically, the best agreement. Conclusion: Differences in prediction equation are minimal compared to calorimetry. Prediction equation could be useful in the management of children with BPD.

Effect of preterm birth on exercise capacity: A systematic review and meta‐analysis

“…2,26 They may also have increased frequency of respiratory infections in infancy 27 and have been reported to have increased arterial systolic blood pressure in childhood. 7 Furthermore, they have altered body composition 28 and _ VO 2 max, as expressed in terms of body mass, tends to be underestimated in heavier subjects and overestimated in lighter subjects. 29 Taken together, the increased risk factors leading to cardiorespiratory illness could potentially have an effect on these children's exercise capacity, especially those who developed BPD in infancy.…”

Assessment of Metabolic and Nutritional Imbalance in Mechanically Ventilated Multiple Trauma Patients: From Molecular to Clinical Outcomes

“…Suman et al studied the critically ill patient with burns, and also showed significant differences between measured and calculated EE as follows: IC vs. Schofield-HW (mean difference, −64.7 to −22.4 kcal/day); IC vs. Harris-Benedict (mean difference, 640 ± 555 kcal/day); and IC vs. Food and Agriculture Organization, World Health Organization, and the United Nations University (FAO/WHO/UNU) (mean difference, 652 ± 559 kcal/day) [126]. Bott et al reported similar results following a study that included 52 pediatric patients with bronchopulmonary dysplasia as follows: IC vs Harris-Benedict (mean difference, −15 ± 33.3); IC vs. Schofield-W (−51.3 to −2.0), Schofield-HW (−67.7 to −22.4); and IC vs. FAO/WHO/UNU (−47.5 to 7.4) [127,128].…”

Agreements between Indirect Calorimetry and Prediction Equations of Resting Energy Expenditure in End-Stage Renal Disease Patients on Continuous Ambulatory Peritoneal Dialysis

“…Moreover, results are similarly conflicting in patients with different diseases. Bott et al showed that the HBE and Schofield equations showed best agreement with measured REE values in children with bronchopulmonary dysplasia and in healthy children, respectively 9. However, Suman et al reported that equations underestimated measured REE values, and that the Schofield equation produced results that were closer to measured REE values in children with severe burns 10.…”