Comparison of proximate compositions, antioxidant, and antiproliferative activities between blueberry andSageretia thea(Osbeck) M.C.Johnst fruit produced in Jeju Island

Abstract

This study was aimed to evaluate and compare the proximate composition, antioxidant and antiproliferative activities of Sageretia thea (Osbeck) M.C.Johnst (S. thea) fruit and blueberry. The calorific value, crude protein, crude fat, crude ash, and carbohydrate were higher in S. thea fruit than in blueberry. S. thea fruit and blueberry have different profile of free sugars, in which amounts of fructose, glucose, and maltose were much higher in S. thea fruit than in blueberry. The methanol extracts of S. thea fruit contain higher amounts of total polyphenol and anthocyanin compared to those of blueberry extracts. In additions, 2,2-diphenyl-1-picrylhydrazyl (DPPH), alkyl, and 2,2'-azinobis(3-ethylbenzothiazoline-6-sulphonic acid) (ABTS) radical scavenging activities are greater in S. thea fruit extracts. Ethyl acetate fractions and n-butanol fractions of S. thea fruit and blueberry show the most potent scavenging activity in DPPH-, alkyl-, and ABTS-radical scavenging assay. The ethyl acetate fractions of S. thea fruit and blueberry are the richest fraction in polyphenol contents while the n-butanol fractions of those are the highest fraction in anthocyanin contents. Furthermore, both S. thea fruit and blueberry extracts protect human dermal fibroblast cells against a H 2 O 2 -induced oxidative stress. The antiproliferative activities of n-hexane and chloroform fraction from S. thea fruit and blueberry were observed in AGS human gastric cancer and MDA-MB-231 human breast cancer cells. Therefore, our results suggest for the first time that the antioxidant and antiproliferative activities of S. thea fruit is comparable to that of blueberry and the nutritional value of the former is even superior to that of the latter.

Effects of Lonicera caerulea extract on adipocyte differentiation and adipogenesis in 3T3-L1 cells and mouse adipose-derived stem cells (MADSCs)

“…국내에서는 강 원도와 함경도, 그리고 한라산 능선 지역에서 생산되고 있 다. 댕댕이나무에 관한 연구로는 항산화 활성 및 성분 분 석에 대한 연구가 진행 되었고 [8,9] 알코올성 손상 간기능 개선 효과에 대한 연구 [10] 면역 [11], 항암 [12]등에 효과 적이며 특히 항산화 효과는 방사선 치료 시 회복에 도움을 주는 것으로 보고되었다 [13,14]…”

In vitro macrophage activation by Sageretia thea fruits through TLR2/TLR4-dependent activation of MAPK, NF-κB and PI3K/AKT signalling in RAW264.7 cells

“…The fruits of S. thea were similar in colour to the blueberry, one of the representative berries, and are about twice as small as a blueberry. However, it has been reported that the fruits of S. thea have higher bioactive and nutritional content than blueberry (Ko et al, 2017). In contrast to the leaves and branches of S. thea that have been used for medicinal purposes, the fruits of S. thea have been used primarily for edible purposes, and recently have been reported to exhibit whitening activity via protein kinase B (AKT)/ glycogen synthase kinase-3 beta (GSK3β) signalling pathway (Ko et al, 2018).…”

Antioxidant efficacy of Jeju crop extracts using Jeju lava seawater as a solvent

“…제주산 과일 또는 채소의 항산화 효과에 관한 연구는 '제 주산 진귤, 하귤, 온주밀감의 항산화 활성 비교 (Hyon et al 2010)', '제주산 참다래의 품종 및 숙도에 따른 항산화 활성 비교 (Oh et al 2011)', '제주산 청귤의 착즙액, 착즙박, 원물의 항산화 및 항균 활성 비교 (Choi et al 2019)', '제주산 블루베 리와 상동열매의 일반성분, 항산화 및 항증식 활성 비교 (Ko et al 2017)', '제주산 당근과 벨기에산 파스닙의 항산화 활성 비교 (Park et al 2022)' 등 다양하게 진행되고 있다. 한편, 현재 까지 제주 물 산업 연구는 '제주 물의 기능성 및 혼합음료 개 발 설정에 관한 연구 (Ko et al 2011)', '삼다수의 당뇨병 치료 효과 (Koh et al 2013)' 등 삼다수의 우수성에 관한 연구가 진 행되었다.…”