Comparison of propolis from <i>Apis mellifera</i>
and <i>Tetragonisca angustula</i>

Pereira, Alberto dos Santos; Bicalho, Beatriz; Neto, Francisco Radler de Aquino

doi:10.1051/apido:2003023

Cited by 29 publications

(9 citation statements)

References 13 publications

(12 reference statements)

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“…Bees use it to seal holes in their hives, smooth out the internal walls, and protect the entrance against intruders. It also acts as a natural antibiotic to prevent bacterial, viral, or fungal infections within the hive [1][2][3][4]. Bees collect the resin from the cracks in the bark and leaf buds of different trees, including different species of poplars, conifers (e.g.…”

Section: Introductionmentioning

confidence: 99%

Advances in the Propolis Chemical Composition between 2013 and 2018: A Review

Šturm

Ulrih

2019

eFood

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Propolis is a lipophilic sticky substance collected by bees that has been used by humans for centuries. Owing to its healing, antioxidant, and other medicinal properties, its chemical composition has been widely studied. Most pharmacological properties of propolis have been attributed to its phenols and terpenes, mainly flavonoids, phenolic acids, and their derivatives. More than 500 components of propolis were known from different parts of the world until 2012. In this article, 305 new constituents of propolis described between 2013 and 2018 are being reviewed, with 19 additional compounds that were discovered between 2011 and 2012, and were excluded from a similar previous review article. Altogether more than 850 compounds were isolated from propolis until 2018.

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Section: Introductionmentioning

confidence: 99%

Advances in the Propolis Chemical Composition between 2013 and 2018: A Review

Šturm

Ulrih

2019

eFood

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“…Known pharmacological activities generally refer to propolis produced by Apis mellifera , the most common bee species in many countries and the main producer of honey in those countries [7]. However, some of these activities have also been observed in propolis produced by other bee species, including members of the tribe Meliponini [6,8].…”

Section: Introductionmentioning

confidence: 99%

Antimicrobial activity against oral pathogens and immunomodulatory effects and toxicity of geopropolis produced by the stingless bee Melipona fasciculata Smith

Libério

Pereira

Dutra

et al. 2011

BMC Complement Altern Med

101

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BackgroundNative bees of the tribe Meliponini produce a distinct kind of propolis called geopropolis. Although many pharmacological activities of propolis have already been demonstrated, little is known about geopropolis, particularly regarding its antimicrobial activity against oral pathogens. The present study aimed at investigating the antimicrobial activity of M. fasciculata geopropolis against oral pathogens, its effects on S. mutans biofilms, and the chemical contents of the extracts. A gel prepared with a geopropolis extract was also analyzed for its activity on S. mutans and its immunotoxicological potential.MethodsAntimicrobial activities of three hydroalcoholic extracts (HAEs) of geopropolis, and hexane and chloroform fractions of one extract, were evaluated using the agar diffusion method and the broth dilution technique. Ethanol (70%, v/v) and chlorhexidine (0.12%, w/w) were used as negative and positive controls, respectively. Total phenol and flavonoid concentrations were assayed by spectrophotometry. Immunotoxicity was evaluated in mice by topical application in the oral cavity followed by quantification of biochemical and immunological parameters, and macro-microscopic analysis of animal organs.ResultsTwo extracts, HAE-2 and HAE-3, showed inhibition zones ranging from 9 to 13 mm in diameter for S. mutans and C. albicans, but presented no activity against L. acidophilus. The MBCs for HAE-2 and HAE-3 against S. mutans were 6.25 mg/mL and 12.5 mg/mL, respectively. HAE-2 was fractionated, and its chloroform fraction had an MBC of 14.57 mg/mL. HAE-2 also exhibited bactericidal effects on S. mutans biofilms after 3 h of treatment. Significant differences (p < 0.05) in total phenol and flavonoid concentrations were observed among the samples. Signs toxic effects were not observed after application of the geopropolis-based gel, but an increase in the production of IL-4 and IL-10, anti-inflammatory cytokines, was detected.ConclusionsIn summary, geopropolis produced by M. fasciculata can exert antimicrobial action against S. mutans and C. albicans, with significant inhibitory activity against S. mutans biofilms. The extract with the highest flavonoid concentration, HAE-2, presented the highest antimicrobial activity. In addition, a geopropolis-based gel is not toxic in an animal model and displays anti-inflammatory effect.

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“…[84] Propolis Propolis is a highly complex resinous mixture collected by bees from plant exudates, mixed with saliva and beeswax inside the hive, and used for various purposes, including building, protecting, and adapting their nests. [85] Propolis collection is considered secondary to nectar or pollen collection, and the amount of propolis used in nests can vary widely between colonies; [43] The chemical composition of propolis is strongly influenced by the variety of plants from which the bees collect it, so propolis can vary in chemical composition from one region to another and from one colony to another. In the literature, T. angustula propolis presents a variety of compounds such as flavonoids, phenolic acids, coumarins and terpenoids.…”

Section: Honeymentioning

confidence: 99%

“…PropolisObtusifoliol; β-amirine; lupenone; cycloartenol; lupeol; Friedour-7-en-3-one; Friedour-7-en-3-ol; lupeol acetate; β-amirine acetate[43] Propolis Butanediol; β-amirine acetate; lupeol; lupeol acetate; friedour-7-en-3-one; β-amirine; lupenone; obtusifoliol; octacosanoic acid; hexacosanoic acid; tetracosanoic acid; caffeic acid; p-coumaric acid; hexadecanoic acid; hydracrylic acid; lactic acid; succinic acid; glycerol hydrocinnamic acid; erythritol; p-hydroxybenzoic acid; p-hydroxy-dihydrocinnamic acid [43] Propolis Etylamine; hydroxybutyric acid; lactic acid; hydracrylic acid; hydroxymethylbutyric acid; butanetriol; malonic acid; valine; glycerol; phosphoric acid; succinic acid; diidroxypropanoic acid; fumaric acid; hydrocinnamic acid; erythritol; malic acid; hexanedioic acid; erythrose 5-oxo-proline; p-hydroxybenzoic acid; p-hydroxyphenylacetic acid; p-hydroxy-dihydrocinnamic acid; o-cumaric acid; dihydroxybenzoic acid; fructose; p-coumaric acid; hexadecanoic acid; linoleic acid; oleic acid; octadecanoic acid; tetracosanoic acid; octacosanoic acid; cycloartenol; β-amirine acetate; lupeol acetate [43] Propolis 3,5-Diprenyl-4-hydroxycinnamic acid; 3-Prenyl-4 hydroxycinnamic acid; 2,2-Dimethyl-8-prenyl-2H-1-benzopiran-6-propenoic acid; cinnamic acid derivative Geopropolis Caffeic acid; cinnamic acid; chlorogenic acid; ferulic acid; hispidulin; protocatechuic acid; quercetin; rutin; α-methoxyphenylacetic acid; gallic acid; syringic acid; vanillic acid; aringenin; galangin; apigenin [44] Geopropolis 4-Hydroxybenzoic acid; chlorogenic acid; caffeic acid; ferulic acid; p-coumaric acid; quercetin; rutin; galangin; kaempferol; apigenin; ellagic acid; hesperetin; pinocembrine; chrysin; luteolin [19] Geopropolis Dihydrocanferide; terpenic acids; cupressic acid; isocupressic acid; gatalic acid; 15-acetoxy-cupressic acid [45] TPC: Total phenolic content; TFC: Total flavonoid content; NMR: Nuclear magnetic resonance; HPLC-DAD: High Performance Liquid Chromatography with Diode Array Detection; HT-HRGC: High Temperature High Resolution Gas Chromatography; HT-HRGC-MS: High Temperature High Resolution Gas Chromatography Coupled to Mass Spectrometry; ESI-MS/MS: Electrospray Ionisation Mass Spectrometry; GC-MS: Gas Chromatography -Mass Spectrometry; GC-FID: Gas Chromatography with Flame Ionization Detector ; UFLC-PDA-ESI-TOF/MS; High-Performance Liquid Chromatography Coupled to Mass Spectrometer; HPLC-DAD-ESI/MS: High-Performance Liquid Chromatography-Diode Array Detection-Electro-Spray Ionization Mass Spectrometry;…”

mentioning

confidence: 99%

Floral Visitation, Phytochemical and Biological Activities of Bioproducts from Tetragonisca angustula (Hymenoptera, Apidae, Meliponini): A Review

Silva Macêdo,

de Sousa Silveira,

da Silva Sousa

et al. 2023

Chemistry & Biodiversity

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Tetragonisca angustula (Latreille, 1811) is an indigenous neotropical stingless bee, popularly known as “Jataí”, with a wide distribution in the Brazilian territory. T. angustula produces other derivatives such as propolis, geopropolis, fermented (saburá pollen), cerumen and resins, which are important in folk medicine. In this review, the objective was to gather research on the main plant species visited by T. angustula, as well as studies that verified the chemical composition and biological properties of T. angustula bioproducts. The bibliographic review was performed by searching the Scopus, Web of Science, ScienceDirect, and PubMed databases for publications from 2003 to February 2023. We found 78 studies that analyzed the interactions between T. angustula and floral species, with species from the botanical families Fabaceae, Asteraceae, Malvaceae, Bignoniaceae, Solanaceae, Myrtaceae and Lamiaceae being the most reported as the main food sources for this species. The presence of compounds belonging to the class of flavonoids, phenolic acids, terpenoids and alkaloids has been identified by studying the chemical composition of honey, propolis, geopropolis and fermented pollen (saburá) in 21 studies. The data collected in the literature emphasize that these T. angustula products have remarkable biological properties, especially their antibacterial and antioxidant activities.

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Comparison of propolis from Apis mellifera and Tetragonisca angustula

Cited by 29 publications

References 13 publications

Advances in the Propolis Chemical Composition between 2013 and 2018: A Review

Advances in the Propolis Chemical Composition between 2013 and 2018: A Review

Antimicrobial activity against oral pathogens and immunomodulatory effects and toxicity of geopropolis produced by the stingless bee Melipona fasciculata Smith

Floral Visitation, Phytochemical and Biological Activities of Bioproducts from Tetragonisca angustula (Hymenoptera, Apidae, Meliponini): A Review

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