Comparison of Polysomnography Variables in Obstructive Sleep Apnea Patients with or without Excessive Daytime Sleepiness

Abstract

A AB BS S T TR RA AC CT T OOb b j je ec c t ti i v ve e: : Excessive daytime sleepiness (EDS) is a common symptom in patients with obstructive sleep apnea (OSA), and the reason for this could not be fully elucidated. The aim of this study was to compare polysomnographic and demographic features of patients with OSA with or without EDS according to Epworth Sleepiness Scale (ESS). M Ma at te er ri ia al l a an nd d M Me et th ho od ds s: : A total of 82 adult patients who were diagnosed with OSA with polysomnography were retrospectively divided into 2 groups in terms of having EDS (ESS>10) or not (ESS≤10) according to ESS score. R Re es su ul lt ts s: : Forty six patients had an ESS score >10. Patients with OSA suffering from sleepiness were younger (p=0.010), more obese (p=0.039), had higher arousal index (p=0.051) and apnea hypopnea index (AHI) (p=0.036) on polysomnography. There was no gender difference between two groups (p=0.423). Polysomnographic findings revealed that there were no differences in total sleep time, sleep efficiency or overall distribution of sleep stages (N1,N2, N3, REM), or nocturnal mean and minimum saturation (p=0. 516, p=0.790, p=0.674, p=0.852, p=0.677, p=0.137, p=0.286, p=0.353, respectively). On multivariate regression analysis, arousal index, total AHI, and age were effective in determination of ESS score (p<0.001). C Co on nc cl lu us si io on n: : OSA patients with EDS were younger and more obese when compared to OSA patients with no EDS. No single factor was effective for detection of EDS with ESS score. Rather, factors such as severity of OSA, arousal index, and age were collectively decisive.K Ke ey y W Wo or rd ds s: : Sle ep ap ne a, obs truc ti ve; poly som nog raphy Ö ÖZ ZE ET T A Am ma aç ç: : Gün düz uy ku lu luk, obs trük tif uy ku ap ne li (OSA) has ta lar da sık gö rü len, an cak ne deni tam ola rak ay dın la tı la ma mış bir semp tom dur. Ça lış ma da Ep worth uy ku luk luk ska la sı (ESS) so nucu na gö re aşı rı uy ku lu lu ğu olan ve ol ma yan OSA' lı has ta la rın po li som nog ra fik ve de mog ra fik özel lik le ri nin kar şı laş tı rıl ma sı amaç lan dı. G Ge e r re eç ç v ve e Y Yö ön n t te em m l le er r: : Po li som nog ra fi ile OSA ta nı sı konmuş 82 [Ap ne hi pop ne in dek si (AHİ)>15/sa] eriş kin has ta (28 ka dın/54 er kek), ESS so nu cu na gö re gün düz aşı rı uy ku lu lu ğu (GA U) olan (ESS>10) ve ol ma yan (ESS≤10) şek lin de 2 grup ta ret ros pek tif ola rak in ce len di. B Bu ul l g gu u l la ar r: : Has ta lar dan 46'sın da ESS>10 idi. Gün düz uy ku lu lu ğu olan OSA' lı has talar da ha genç (p=0,010) ve obez di (0,039). Bu gru bun po li som nog ra fi le rin de aro u sal in dek si (p=0,051) ve ap ne hi pop ne in dek si (AHİ) da ha yük sek ti (p=0,036). İki grup ara sın da cin si yet fark lı lı ğı gö rül -me di (p=0,423). Po li som nog ra fi le rin de to tal uy ku sü re si, uy ku et kin li ği ya da uy ku ev re le ri nin da -ğı lı mı (N1,N2,N3,REM), nok tur nal or ta la ma sa tu ras yon ve en dü şük sa tu ras yon de ğer le ri açı sın dan, iki grup ara...

Gender differences in the sleep variables contributing to excessive daytime sleepiness among patients with obstructive sleep apnea

“…Previous studies that examined the correlation between sleep study parameters and ESS showed an association between hypoxemia, BMI, and AHI to EDS [ 7 , 20 – 22 ]. Another study, by Gulbar et al, showed significant correlation between the duration of sleep apnea/hypopnea and EDS [ 21 ].…”