Comparison of Plasma Amino Acid Levels of Two Breeds of Japanese Native Chicken 
 and a Commercial Layer Line

Takawaki, Minani; Tanizawa, Hiroshi; Nakasai, Eriko; Shiraishi, Jun-ichi; Kawakami, Shin‐ichi; Oka, Takao; Tsudzuki, Masaoki; Bungo, Takashi

doi:10.3923/ijps.2013.90.93

Cited by 2 publications

(1 citation statement)

References 2 publications

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“…TAU, one of the most abundant free amino acids in many excitable tissues including the brain, skeletal and cardiac muscles, serves many important functions in mammals ( El Idrissi, 2019 ). TAU is rich in the blood of layer-type chickens ( Takawaki et al., 2013 ) and in the liver and thigh muscle of broilers ( Huang et al., 2014 ). TAU level in blood is 6- to 11-fold higher in avian species than in humans ( Szwergold and Miller, 2014 ).…”

Section: Introductionmentioning

confidence: 99%

Effect of substitution of taurine for methionine and additional taurine supplementation on the performance and antioxidative capacity of laying hens

et al. 2023

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Section: Introductionmentioning

confidence: 99%

Effect of substitution of taurine for methionine and additional taurine supplementation on the performance and antioxidative capacity of laying hens

et al. 2023

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Potential of Birds to Serve as Pathology-Free Models of Type 2 Diabetes, Part 2: Do High Levels of Carbonyl-Scavenging Amino Acids (e.g., Taurine) and Low Concentrations of Methylglyoxal Limit the Production of Advanced Glycation End-Products?

Szwergold¹,

Miller²

2014

Rejuvenation Research

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In our previous publication, we reported on the advantages of using birds as a pathology-free model of type 2 diabetes mellitus (T2DM). Using this new perspective, we observed that birds are missing the RAGE gene, considered an important factor in the development of diabetic complications. In this article, we identify two additional Maillard reaction-related characteristics of birds that have the potential to account, in part, for avian ability to cope successfully with chronic hyperglycemia. First, compared to mammals, blood plasma of birds has significantly higher concentrations of taurine and other free amino acids that act as scavengers of reactive carbonyls. Second, there are also indications that avian blood plasma contains lower concentrations of methylglyoxal (MG) due, in part, to its decreased production by avian erythrocytes. Our deductions are based on relatively meager experimental data and are therefore speculative. One certain outcome of our study, however, is the idea that birds can be a useful model for the study of Maillard reactions and etiology of diabetic complications. We anticipate and hope that results of future studies will support the hypothesis identifying MG as a key intermediate in the etiology of diabetic complications. If this is indeed the case, then prevention and control of diabetic complications may become transformed into a more circumscribed, defined, and tractable problem whose goals will be to minimize the production of MG and to maximize its elimination by detoxification or scavenging.

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Comparison of Plasma Amino Acid Levels of Two Breeds of Japanese Native Chicken and a Commercial Layer Line

Cited by 2 publications

References 2 publications

Effect of substitution of taurine for methionine and additional taurine supplementation on the performance and antioxidative capacity of laying hens

Effect of substitution of taurine for methionine and additional taurine supplementation on the performance and antioxidative capacity of laying hens

Potential of Birds to Serve as Pathology-Free Models of Type 2 Diabetes, Part 2: Do High Levels of Carbonyl-Scavenging Amino Acids (e.g., Taurine) and Low Concentrations of Methylglyoxal Limit the Production of Advanced Glycation End-Products?

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