Comparison of physicochemical and thermal properties of choline chloride and betaine-based deep eutectic solvents: The influence of hydrogen bond acceptor and hydrogen bond donor nature and their molar ratios

Mero, Angelica; Koutsoumpos, Spyridon; Giannios, Panagiotis; Moutzouris, K.; Mezzetta, Andrea; Guazzelli, Lorenzo

doi:10.1016/j.molliq.2023.121563

Cited by 27 publications

(10 citation statements)

References 93 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Compared to DES 1, DES 2 has physicochemical properties that favor mass transfer. Indeed, it was found that the viscosity of betaine-based DES decreased as follows: Gly > LevA > EG . Moreover, Mero et al showed that betaine-based DESs are stable at moderate temperature .…”

Section: Resultsmentioning

confidence: 99%

“…Indeed, it was found that the viscosity of betaine-based DES decreased as follows: Gly > LevA > EG. 41 Moreover, Mero et al showed that betaine-based DESs are stable at moderate temperature. 41 Maximum distribution coefficient and selectivity of both DES studied in this work are compared with conventional solvents such as DMSO, DMF, or sulfolane but also with other DES or ILs published in the literature for the separation problem of thiophene from nheptane.…”

Section: ■ Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Desulfurization and Denitrogenation Using Betaine-Based Deep Eutectic Solvents

Islam,

Rubio,

Rafikova

et al. 2024

J. Chem. Eng. Data

View full text Add to dashboard Cite

Two betaine-based deep eutectic solvents (DESs), betaine/glycerol [1:2] and betaine/ethylene glycol [1:3], were used in separation processes encountered in the petroleum industry. Liquid–liquid equilibrium of six ternary systems {thiophene + betaine/glycerol [1:2] or betaine/ethylene glycol [1:3] + n-heptane}, {pyridine + betaine/glycerol [1:2] or betaine/ethylene glycol [1:3] + n-heptane}, and {toluene + betaine/glycerol [1:2] or betaine/ethylene glycol [1:3] + n-heptane} were measured at 298.15 K under atmospheric pressure. Phase diagrams of the ternary systems were represented by using the COnductor-like Screening MOdel for Real Solvents (COSMO-RS) and Non Random Two-Liquids equation (NRTL) models. In terms of selectivity and capacity values, betaine/ethylene glycol seems to be the most efficient deep eutectic solvent (DES) in this study. Optimal conditions for the separation process of thiophene, pyridine, or toluene from n-heptane were determined using synthetic fluids composed of n-heptane and 5% of thiophene, pyridine, or toluene. In all cases, the optimal conditions for the extraction were observed with a mass ratio m DES/m sample = 2 and a temperature fixed at 293.15 K. A fourth stage extraction using betaine/ethylene glycol [1:3] allows to remove 99.7% of pyridine and 57.5% of thiophene.

show abstract

Section: Resultsmentioning

confidence: 99%

Section: ■ Introductionmentioning

confidence: 99%

Desulfurization and Denitrogenation Using Betaine-Based Deep Eutectic Solvents

Islam,

Rubio,

Rafikova

et al. 2024

J. Chem. Eng. Data

View full text Add to dashboard Cite

show abstract

“…They have been recognized as "solvents for the 21st century" and have shown promise in biocatalytic reactions [16]. DESs offer remarkable tunability by adjusting the hydrogen bond acceptors and donors, as also noted in recent research [17]. This flexibility underpins their wide range of applications.…”

Section: Introductionmentioning

confidence: 94%

Tuning Mechanical Characteristics and Permeability of Alginate Hydrogel by Polyvinyl Alcohol and Deep Eutectic Solvent Addition

Menegatti,

Kopač,

Žnidaršič-Plazl

2024

Bioengineering

View full text Add to dashboard Cite

Alginate-based hydrogels are widely utilized for various applications, including enzyme immobilization and the development of drug delivery systems, owing to their advantageous characteristics, such as low toxicity, high availability and cost-effectiveness. However, the broad applicability of alginate hydrogels is hindered by their limited mechanical and chemical stability, as well as their poor permeability to hydrophobic molecules. In this study, we addressed the mechanical properties and chemical resistance of alginate hydrogels in a high-pKa environment by the copolymerization of alginate with polyvinyl alcohol (PVA). The addition of PVA resulted in a threefold improvement in the shear modulus of the copolymeric hydrogel, as well as enhanced chemical resistance to (S)-α-methylbenzylamine, a model molecule with a high pKa value. Furthermore, we addressed the permeability challenge by introducing a betaine–propylene glycol deep eutectic solvent (DES) into the PVA-alginate copolymer. This led to an increased permeability for ethyl 3-oxobutanoate, a model molecule used for bioreduction to chiral alcohols. Moreover, the addition of the DES resulted in a notable improvement of the shear modulus of the resulting hydrogel. This dual effect highlights the role of the DES in achieving the desired improvement of the hydrogel as an immobilization carrier.

show abstract

“…The greater the number of -OH functional groups present in the HBD, and consequently the increased potential for hydrogen bond formation, the higher the density of the system [26,27]. The viscosity of NADES represents the degree of resistance exhibited by a fluid, it represents another fundamental parameter that can be used to define their possible applicability as reaction or extraction media [28]. In this study, it is evident that Bet-based NADES exhibit significantly higher viscosity compared to ChCl-based NADES (p < 0.05).…”

Section: Physicochemical Properties Of Nadesmentioning

confidence: 99%

Natural Deep Eutectic Solvent-Based Ultrasound-Assisted Extraction of Flavonoids from Fagopyrum tataricum Bran

Xu,

Da,

et al. 2024

Separations

View full text Add to dashboard Cite

In this study, eleven kinds of flavonoids were identified from F. tataricum bran (FTB) by UPLC-Q-TOF-MS, and HPLC-DAD analysis revealed that four compounds, including rutin, quercetin, kaempferol, and nicotiflorin, were the most significant components. Subsequently, natural deep eutectic solvent-based ultrasound-assisted extraction (NADES-UAE) was employed to extract flavonoids from FTB. Among the six kinds of NADES prepared, choline chloride–ethylene glycol (ChCl-EG) was identified as a promising candidate for extracting flavonoids due to its superior extraction performance. The extraction conditions were statistically investigated using response surface methodology conducted by Box-Behnken design (BBD). The optimal operational conditions were as follows: ultrasonic time 268 s, ultrasonic temperature 76 °C, and liquid–solid ratio 43 mL/g, which resulted in a high total flavonoid yield of 40.29 mg/g. Afterwards, the efficient extraction mechanism of NADES-UAE was comprehensively explored through FT-IR spectra, COSMO model, and microstructural analysis. In conclusion, NADES-UAE extraction is considered a green, efficient, and sustainable method for FTB flavonoids.

show abstract

Comparison of physicochemical and thermal properties of choline chloride and betaine-based deep eutectic solvents: The influence of hydrogen bond acceptor and hydrogen bond donor nature and their molar ratios

Cited by 27 publications

References 93 publications

Desulfurization and Denitrogenation Using Betaine-Based Deep Eutectic Solvents

Desulfurization and Denitrogenation Using Betaine-Based Deep Eutectic Solvents

Tuning Mechanical Characteristics and Permeability of Alginate Hydrogel by Polyvinyl Alcohol and Deep Eutectic Solvent Addition

Natural Deep Eutectic Solvent-Based Ultrasound-Assisted Extraction of Flavonoids from Fagopyrum tataricum Bran

Contact Info

Product

Resources

About