Comparison of Physical and Morphological Properties of Mandura Bhasma and Iron Oxide Nanoparticles

Abstract

There are several standardization techniques for assuring the quality of Ayurvedic medicines. Bhasmas are nanoparticle medicines, which are used in Ayurveda and quality assurance of these medicines plays an important role in the action of these remedies. As a physiochemical test for this quality assurance, Mandura bhasma was chosen and various physiochemical analysis was done, it was compared with synthesized iron oxide, to get the same physical and chemical parameters. FTIR studies were made for confirming the presence of iron oxide in the sample. XRD was taken on both the samples and the particle size was determined. Morphology of the samples were studied using SEM. Composition was determined using EDAX. The study reveals that the composition of the bhasmas are important in each formulation and it can be studied using EDAX. The impurities can be exactly determined by EDAX, which may be deliberately introduced in the drug for the effectiveness of the Ayurvedic drug. From this study, it is seen that XRD analysis is less important physiochemical analysis than the other methods mentioned in this paper. Further, the morphology from SEM shows that the bhasmas are a combination of various sized nanoparticles which has different spheres of action due to its size, which shows that the same bhasma can be used for different ailments due to its size effect.

Characterization of Zinc Oxide Based Nano Siddha Medicine Naga Parpam – Potential Nutritive Supplement in Cancer

“…Due to difference in the size of the drug, size dependent biological functions also differ. Hence, the same drug is given for different ailments and the drug has different degrees of action 33 . This proves the size dependence of this medicine.…”