Comparison of phenolic components and biological activities of two Centaurea sp. obtained by three extraction techniques

Albayrak, Sevil; Atasagun, Bayram; Aksoy, Ahmet

doi:10.1016/j.apjtm.2017.06.010

Cited by 40 publications

(31 citation statements)

References 38 publications

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“…In this study, the ultrasound assisted extraction technique was used. As per to previous study (Albayrak et al, 2017), ultrasonic extraction gave better extract with larger amount of extractive substances and stronger antioxidant and antimicrobial activities than the extracts prepared using other techniques (Soxhlet extraction, Maceration). The Result implied that C. iberica aerial parts hydromethanolic extract contains good phenolic content.…”

Section: Discussionsupporting

confidence: 78%

Phytochemical Analysis, Total Phenolic Content, Hemolytic and Antihemolytic Activities of Centaurea iberica (Asteraceae)

Joujeh¹

2020

SJKFU

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Several plants contain chemical substances that have various biological activities that might cause harmful effects to cellular membranes. This work deals with Centaurea iberica (Iberian starthistle) plant. The objective of this study is to identify the main chemical groups in the methanolic extract 80% of the plant, determine its total phenolic content, evaluate its toxic effect on human erythrocytes in addition to assessing its activity in protecting normal and glucose-6-phosphate dehydrogenase (G6PD) enzyme-deficient human erythrocytes membranes against oxidative hemolysis. Phytochemical analysis revealed that C. iberica extract contains several bioactive compounds. The results also showed that the plant extract contained good level of total phenolic compounds. The extract exhibited low hemolytic effect. It also showed excellent activity in the protection of normal and G6PDdeficient human erythrocytes against oxidative hemolysis.

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Section: Discussionsupporting

confidence: 78%

Phytochemical Analysis, Total Phenolic Content, Hemolytic and Antihemolytic Activities of Centaurea iberica (Asteraceae)

Joujeh¹

2020

SJKFU

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“…drabifolia and C. lycopifolia had 55.00, 24.70, and 28.82 mg GAE/g, respectively. Albayrak et al [1] studied different extracts of Centaurea obtained by maceration, soxhlet, and sonication with methanol; the best TPC (12.92 mg GAE/g) was detected in ultrasonic extract of C. amaena.…”

Section: Total Phenolic Content (Tpc)mentioning

confidence: 99%

“…Recently, free radicals have been the concern of several researches. These free radicals are naturally produced, in cellular systems, in the form of endogenous reactive from oxygen/nitrogen species (ROS/RNS) through natural metabolic reactions [1]. In addition, several external sources (e.g., pollution, UV radiations, alcohol, smoking, and chemicals) raise oxidative stress, causing an overproduction of free radicals in the human body [2].…”

Section: Introductionmentioning

confidence: 99%

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Screening of Antioxidant Potentials and Bioactive Properties of the Extracts Obtained from Two Centaurea L. Species (C. kroumirensis Coss. and C. sicula L. subsp sicula)

et al. 2020

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Herbal medicines, dietary supplements, or infusions with health promoting effects can note strong consumer demand. Hence, researchers and scientists have been increasingly focusing on the promotion of medicinal plants. In this respect, the present study has the evaluation of the biological properties of different extracts (hexane, chloroform, methanol, ultrasonic, essential oil, and supercritical) obtained from two Centaurea species (C. kroumirensis (Coss.) and C. sicula L. subsp sicula) as purpose. Antioxidative activities were assessed by in vitro assays including total phenolic content, free radical scavenging assay and ferric ion reducing power. Among the fourteen extracts examined, the highest total phenolic content (TPC) and antioxidant abilities were recorded in ultrasonic ethanol extracts of both Centaurea species. Additionally, these extracts exhibited a noticeable strong protective effect of the human skin fibroblast cell line (HS-68) that was exposed to oxidative stress induced by hydrogen peroxide. According to our results, the sonication with ethanol might be an ideal, rapid, and eco-friendly extraction method for obtaining a polyphenol-rich extract that exhibited high antioxidant activity. The results presented herein suggest that Centaurea species could be promoted as an antioxidant resource that could be exploited for the development of nutraceuticals or in pharmacology industry.

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“…Türkiye'deki en büyük üçüncü cins olan Centaurea'nın 217 türü vardır ve endemizm oranı yaklaşık %68'dir [1]. Centaurea türleri bazı ülkelerde ve Türkiye'de geleneksel olarak apseler, mide ve baş ağrısı, astım, hemoroid, inflamatuar, ürogenital, endokrin hastalıkları, gastrointestinal semptomlar, kardiyovasküler hastalıklar, parazitik, mikrobiyal enfeksiyonlar gibi çeşitli rahatsızlıkları tedavi etmek için kullanılmaktadır [2][3][4][5][6][7][8][9]. Centaurea ile ilgili yapılan bazı çalışmalarda antimikrobiyal, antifungal, antiplasmodiyal [8,10], antiülserojenik [11], antiviral [12], sitotoksik ve apoptotik [13] etkileri belirlenmiştir.…”

Section: Introductionunclassified

Centaurea fenzlii Reichardt Özütünün Antioksidan Özellikleri ve Enzim İnhibisyon Etkisinin Belirlenmesi

Yırtıcı¹

2019

Bitlis Eren Üniversitesi Fen Bilimleri Dergisi

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Bu çalışmada Centaurea fenzlii Reichardt bitkisinin antioksidan özellikleri ve çeşitli enzimler üzerine inhibe edici etkisi araştırıldı. Bu amaçla çiçeklenme döneminde toplanan Centaurea fenzlii Reichardt'ın toprak üstü kısımları farklı polariteye sahip çözücülerde maserasyon yöntemi kullanılarak çözüldü ve ekstreleri elde edildi. Çalışmalara metanol ekstresi ile devam edildi. Metanol ekstresinin toplam fenolik ve flavonoid içerikleri sırasıyla, 16,72 mg GAE/g ka ve 173,16 mg KAE/g ka olarak belirlendi. Antioksidan kapasiteleri demir indirgeyici gücü (FRAP) için 0,256 mmol TE/g ka, bakır indirgeyici gücü (CUPRAC) için 0,878 mmol TE/g ka, ABTS için 0,354 mmol TE/g ka ve DPPH için 0,661 mmol TE/g ka olarak saptandı. Ayrıca, ekstrelerinin kolinesteraz, α-amilaz, α-glukozidaz ve tirozinaz enzimlerine karşı inhibe edici etkileri de belirlendi. Enzim inhibisyon etkisi sırasıyla, α-Glukozidaz için 0,331 mmol AKE/g ka, α-Amilaz için 0,354 mmol AKE/g ka, AChE için 0,367 mmol GAE/g ka, BChE için 0,878 mmol GAE/g ka ve Tirozinaz için mmol 0,256 KE/g ka olarak bulundu.

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Comparison of phenolic components and biological activities of two Centaurea sp. obtained by three extraction techniques

Abstract: This study confirms that ultrasonic extraction may be an ideal, simple and rapid method to obtain polyphenol-rich extracts have antioxidant as well as antibacterial activity from both Centaurea species especially from C. amaena.

Cited by 40 publications

References 38 publications

Phytochemical Analysis, Total Phenolic Content, Hemolytic and Antihemolytic Activities of Centaurea iberica (Asteraceae)

Phytochemical Analysis, Total Phenolic Content, Hemolytic and Antihemolytic Activities of Centaurea iberica (Asteraceae)

Screening of Antioxidant Potentials and Bioactive Properties of the Extracts Obtained from Two Centaurea L. Species (C. kroumirensis Coss. and C. sicula L. subsp sicula)

Centaurea fenzlii Reichardt Özütünün Antioksidan Özellikleri ve Enzim İnhibisyon Etkisinin Belirlenmesi

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