Comparison of Peritoneal Fluid and Peripheral Blood pH, Bicarbonate, Glucose, and Lactate Concentration as a Diagnostic Tool for Septic Peritonitis in Dogs and Cats

Bonczynski, Jennifer J.; Ludwig, Lori; Barton, Linda; Loar, Andrew S.; Peterson, Mark E.

doi:10.1053/jvet.2003.50005

Cited by 162 publications

(137 citation statements)

References 7 publications

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“…In human medicine, a number of studies focusing on the variability of pH in fluids from body cavities have been carried out (Gitlin et al 1982, Sahn and Good 1988, Simmen and Baser 1993, Simmen and Blaser 2001, Bonczynski et al 2003, Noh 2003. According to Light (1972), a decrease in the pH of the fluid in the pleural cavities is observed in inflammatory conditions, cancers, acidosis or lupus.…”

Section: Discussionmentioning

confidence: 99%

An analysis of pH, pO2 and pCO2 in the peritoneal fluid of dogs with ascites of various etiologies

Glińska-Suchocka

Sławuta

Jankowski

et al. 2016

Polish Journal of Veterinary Sciences

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The aim of the study was to assess pH, pO 2 and pCO 2 in peritoneal fluid. The study was conducted on a group of 22 dogs with symptoms of ascites. Group 1 consisted of 4 dogs with adenocarcinoma, group 2 -of 6 dogs with glomerulonephritis, group 3 of 8 dogs with hepatic cirrhosis and group 4 of 4 dogs with bacterial peritonitis. An abdominal cavity puncture was performed in all dogs and the fluid was drawn into a heparinized syringe in order to assess pH, pO 2 and pCO 2 . The analysis of pH in the peritoneal fluid revealed statistically significant differences between group 4 and groups 1 (p=0.01), 2 (p=0.01), and 3 (p=0.01). The lowest pH value compared to the other studied groups was recorded in group 4. In group 4, the pO 2 was the lowest compared to the other groups (group 1 p=0.01, group 2 p=0.01, group 3 p=0.01). The value of pCO 2 was the highest in group 4 compared to groups 1, 2, and 3. The study found statistically significant differences in pH, pO 2 and pCO 2 between group 4 (the group of dogs with bacterial peritonitis) and the other groups of dogs. This was probably linked to the pathogenesis of peritonitis. As a result of an inflammatory reaction within the peritoneal cavity, there is an increase in fibrin accumulations leading to a decreased oxygen supply causing the oxidative glucose metabolism to change into a non-oxidative glucose metabolism. This, in turn, causes a decrease in pH, acidosis, and a low oxidoreduction potential. It also impairs phagocytosis and activates proteolytic enzymes which create ideal conditions for the growth of anaerobic bacteria. The obtained results indicate that the pH, pO 2 and pCO 2 may be used to differentiate bacterial peritonitis from ascites of other etiologies.

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Section: Discussionmentioning

confidence: 99%

An analysis of pH, pO2 and pCO2 in the peritoneal fluid of dogs with ascites of various etiologies

Glińska-Suchocka

Sławuta

Jankowski

et al. 2016

Polish Journal of Veterinary Sciences

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“…L'anamnèse et l'examen clinique sont généralement peu spécifiques [13,14]. Un état de choc, une douleur abdominale ou un signe du flot peuvent être mis en évidence (cependant celui-ci n'est détectable que lors d'épanchement de volume supérieur à 40 mL/kg) [15].…”

Section: Péritonite Septique : Une Complication Fréquente Lors De Gisunclassified

Un cas de péritonite septique consécutive à la rupture d’une tumeur stromale gastro-intestinale cæcale

Ménard

Maurey

Fontaine

et al. 2015

Revue Vétérinaire Clinique

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“…Peripheral blood glucose ≥20 mg/dL higher than peritoneal fluid glucose has been shown to be highly predictive of septic peritonitis in dogs and cats. 7 Similarly, lactate concentrations greater in abdominal fluid than in peripheral blood (bloodtoperitoneal fluid lactate concentration difference less than −2.0 mmol/L) is predictive of septic peritonitis in the dog, but not in the cat. 7,8 Intra-abdominal pressure monitoring…”

Section: Abdominocentesismentioning

confidence: 99%

Peritoneal Evaluation

and¹,

Adams²

2012

Advanced Monitoring and Procedures for Small Animal Emergency and Critical Care

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Comparison of Peritoneal Fluid and Peripheral Blood pH, Bicarbonate, Glucose, and Lactate Concentration as a Diagnostic Tool for Septic Peritonitis in Dogs and Cats

Abstract: The difference between blood and peritoneal fluid glucose concentrations should be used as a more reliable diagnostic indicator of septic peritoneal effusion than peritoneal fluid glucose concentration alone.

Cited by 162 publications

References 7 publications

An analysis of pH, pO2 and pCO2 in the peritoneal fluid of dogs with ascites of various etiologies

An analysis of pH, pO2 and pCO2 in the peritoneal fluid of dogs with ascites of various etiologies

Un cas de péritonite septique consécutive à la rupture d’une tumeur stromale gastro-intestinale cæcale

Peritoneal Evaluation

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