Comparison of percutaneous radiofrequency ablation and CyberKnife^®for initial solitary hepatocellular carcinoma: A pilot study

Abstract

The occurrence of adverse events is a concern, but CyberKnife(®) treatment is likely to become an important option for local treatment of early HCC.

Advances in Stereotactic Body Radiation Therapy for Hepatocellular Carcinoma

“…Abdominal compression with 4D-CT have also been used to reduce respiratory motion 19,21,50,52 as has respiratory gating 29,32,41 and intra-fraction tracking of peri-tumoral implanted fiducials 22,30,34,42,48 or external surface markers 20,22,30,43,48 (which requires daily imaging to ensure the adopted breathing model remains satisfactory). Free breathing with 4D-CT, with individualised margins to account for respiration, have also been employed 23 .…”

Stereotactic body radiation therapy for early hepatocellular carcinoma: a retrospective analysis of the South Australian experience

“…A higher rate of SAEs (11% versus 5%) was also associated with RFA in this study. A further retrospective study found equivalent 1‐year local control rates (97%) but an increase in late SAEs in the SBRT group . Taken together, these studies suggest a need for randomized studies comparing SBRT with RFA in this setting.…”

Clinical outcomes of stereotactic body radiotherapy for elderly patients with hepatocellular carcinoma

“…Historically, the role of radiation therapy for HCC has been limited by the risk of radiation‐induced liver damage. A large volume of evidence published in the last several years argues that SBRT can be effective in HCC and liver metastasis . However, little has been reported on the efficacy and safety of SBRT in elderly patients.…”

“…A large volume of evidence published in the last several years argues that SBRT can be effective in HCC and liver metastasis. 10,11 However, little has been reported on the efficacy and safety of SBRT in elderly patients.…”