Comparison of patient responses to high- and low-osmolality contrast agents injected intravenously

Bagg, M. N. J.; Horwitz, Thomas; Bester, Lourens

doi:10.2214/ajr.147.1.185

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1989

1999

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Cited by 12 publications

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“…It is for this reason that the present study was performed. Previous reports have indicated a potential reduction in minor side effects when low osmolality CM are utilized (1,(7)(8)(9)(10)(11). None of these reports deal specifically with the pédiatrie patient, nor with the CT environment, which is unique in that the patient is frequently not in a fasting state but has deliberately been given oral CM prior to the i.v.…”

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confidence: 99%

Comparison of Intravenous Contrast Agents for CT Studies in Children

Cohen¹,

Herman²,

Herron³

et al. 1992

Acta Radiol

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One hundred and eighty children undergoing CT examination were randomly allocated to receive meglumine diatrizoate, iohexol, or iopamidol as their i.v. contrast agent. Minor side effects were detected in 85% of children receiving meglumine diatrizoate, in 18% of those receiving iohexol, and in 36% of those receiving iopamidol. Because many of these minor side effects cause patient motion or delay scanning after contrast medium injection, they potentially degrade image quality. These findings are an indication for the use of low osmolarity contrast agents for i.v. use in pédiatrie CT imaging.

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confidence: 99%