Comparison of Patient-reported Health-related Quality of Life Between Open Radical Cystectomy and Robot-assisted Radical Cystectomy with Intracorporeal Urinary Diversion: Interim Analysis of a Randomised Controlled Trial

Mastroianni, Riccardo; Tuderti, Gabriele; Anceschi, Umberto; Bove, Alfredo Maria; Brassetti, Aldo; Ferriero, Mariaconsiglia; Zampa, Ashanti; Giannarelli, Diana; Guaglianone, Salvatore; Gallucci, Michele; Simone, Giuseppe

doi:10.1016/j.euf.2021.03.002

Cited by 66 publications

(54 citation statements)

References 14 publications

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“…Interestingly, the data from the paper on robot-assisted technique did not prove the UD type to be a game-changer in the cohort of patients undergoing RC as far as pentafecta attainment is concerned (23). Furthermore, a recent randomized controlled trial comparing robot-assisted and open approaches in terms of quality of life revealed the superiority of the latter in terms of urinary symptoms and problems (43). Clinical and pathological staging regarding LNs appeared not to be the factor determining the chance of achieving pentafecta in the multivariable model.…”

Section: Discussionmentioning

confidence: 99%

The View Outside of the Box: Reporting Outcomes Following Radical Cystectomy Using Pentafecta From a Multicenter Retrospective Analysis

Zapała

Ślusarczyk

Korczak³

et al. 2022

Front. Oncol.

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We aimed at characterization of the patients undergoing radical cystectomy (RC) using the prognostic model (a modified pentafecta). In the multicenter retrospective study, we enrolled 304 patients with bladder cancer (pTis-4N0-2M0) who underwent RC between 2015 and 2020 in experienced centers. The definition of the pentafecta was as follows: no Clavien–Dindo grade III–V complications at 90 days and no long-term complications related to urinary diversion <12 months, negative surgical margins, ≥10 lymph nodes (LNs) resected, and no recurrence ≤12 months. RC-pentafecta achievement rate was 22% (n = 67), varying from 47% to 88% attainment rate for different pentafecta components, and was the lowest for sufficient LN yield. Both 12-month recurrence-free survival (RFS) and cancer-specific mortality were compromised in pentafecta failers compared with achievers (57.8% vs. 100% and 33.8% vs. 1.5%, respectively). The following were identified as crucial predictors of RC pentafecta achievement: modality of the surgery, type of urinary diversion, histological type of bladder cancer, advanced staging, and elevated preoperative serum creatinine. In conclusion, we found that the pentafecta achievement rate was low even in high-volume centers in patients undergoing cystectomy. The complexity of the procedure directly influenced the attainment rate, which in turn led to an increase in cancer-specific mortality rate among the pentafecta failers.

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Section: Discussionmentioning

confidence: 99%

The View Outside of the Box: Reporting Outcomes Following Radical Cystectomy Using Pentafecta From a Multicenter Retrospective Analysis

Zapała

Ślusarczyk

Korczak³

et al. 2022

Front. Oncol.

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“…Radical cystectomy has been the surgical standard to treat patients suffering from muscle-invasive bladder cancer. Though there is a significant reduction in the estimated blood loss (EBL), the blood transfusion rate, and the length of stay in robotic-assisted radical cystectomy (RARC) compared to those in open radical cystectomy (ORC), the complications and the positive margin status have been found to be similar [ 61 , 62 , 63 , 64 , 65 , 66 , 67 , 68 ]. Although the role of RARC is controversial, it has become an acceptable alternative to open surgery by some guideline organizations, including the European Association of Urology [ 62 ].…”

Section: Robotic Surgerymentioning

confidence: 99%

Artificial Intelligence and Its Impact on Urological Diseases and Management: A Comprehensive Review of the Literature

Hameed

Dhavileswarapu

Raza

et al. 2021

JCM

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Recent advances in artificial intelligence (AI) have certainly had a significant impact on the healthcare industry. In urology, AI has been widely adopted to deal with numerous disorders, irrespective of their severity, extending from conditions such as benign prostate hyperplasia to critical illnesses such as urothelial and prostate cancer. In this article, we aim to discuss how algorithms and techniques of artificial intelligence are equipped in the field of urology to detect, treat, and estimate the outcomes of urological diseases. Furthermore, we explain the advantages that come from using AI over any existing traditional methods.

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“…Radical cystectomy has been the surgical standard to treat patients suffering from muscle-invasive bladder cancer. Though there is a significant reduction in the estimated blood loss (EBL), the blood transfusion rate, and the length of stay in robotic-assisted radical cystectomy (RARC) compared to those in open radical cystectomy (ORC), the complications and the positive margin status have been found to be similar [61][62][63][64][65][66][67][68]. Although the role of RARC is controversial, it has become an acceptable alternative to open surgery by some guideline organizations, including the European Association of Urology [62].…”

Section: Urologic Oncologymentioning

confidence: 99%

Minimally Invasive Urological Procedures and Related Technological Developments

2021

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Cover image courtesy of Bhaskar Somani © 2021 by the authors. Articles in this book are Open Access and distributed under the Creative Commons Attribution (CC BY) license, which allows users to download, copy and build upon published articles, as long as the author and publisher are properly credited, which ensures maximum dissemination and a wider impact of our publications.The book as a whole is distributed by MDPI under the terms and conditions of the Creative Commons license CC BY-NC-ND.

show abstract

Comparison of Patient-reported Health-related Quality of Life Between Open Radical Cystectomy and Robot-assisted Radical Cystectomy with Intracorporeal Urinary Diversion: Interim Analysis of a Randomised Controlled Trial

Cited by 66 publications

References 14 publications

The View Outside of the Box: Reporting Outcomes Following Radical Cystectomy Using Pentafecta From a Multicenter Retrospective Analysis

The View Outside of the Box: Reporting Outcomes Following Radical Cystectomy Using Pentafecta From a Multicenter Retrospective Analysis

Artificial Intelligence and Its Impact on Urological Diseases and Management: A Comprehensive Review of the Literature

Minimally Invasive Urological Procedures and Related Technological Developments

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