Comparison of parameters for left ventricular volumes and function between echocardiography and cardiovascular magnetic resonance in a large group of cardiac patients

André, Florian; Çelik, Cihan; Abdel-Aty, Hassan; Santos, Maria Fernanda Braggion; Giannitsis, Evangelos; Katus, Hugo A.; Steen, Henning

doi:10.1186/1532-429x-15-s1-e74

Cited by 3 publications

(3 citation statements)

References 0 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…In this setting, the Teichholz calculation performs well 14 —a recent study showed closer values than biplane ejection fraction assessed using the gold standard of cardiovascular magnetic resonance. 15 Visual assessment, despite its semiqualitative nature, is also accurate when undertaken by experienced practitioners. 16 17 Abnormal systolic function leads to a formal biplane volumetric assessment of ejection fraction, classified as follows: normal ≥60%, mildly impaired 45–59%, moderately impaired 35–44% and severely impaired <35%.…”

Section: Methods and Analysismentioning

confidence: 99%

The OxVALVE population cohort study (OxVALVE-PCS)—population screening for undiagnosed valvular heart disease in the elderly: study design and objectives

et al. 2014

View full text Add to dashboard Cite

IntroductionValvular heart disease (VHD) is an increasingly important cardiac condition, driven by an ageing population and lack of progress in the development of medical therapies. There is a dearth of accurate information to guide decision-makers in the development of strategies to combat VHD, and no population-based study has been performed specifically to investigate its contemporary epidemiology. This document describes the design and methodology of the OxVALVE population cohort study (OxVALVE-PCS), which was conceived to address this need.Methods and analysisParticipants aged 65 years and older attending a participating general practice in Oxfordshire, UK, are invited to attend a screening examination. Exclusion criteria include previously diagnosed VHD, inability to provide consent, terminal illness or excessive frailty. Demographics, a focused cardiovascular history and vital signs are recorded at the initial screening examination, accompanied by an echocardiogram. Any finding of significant VHD triggers a separate, more formal echocardiographic assessment (including acquisition of a three-dimensional dataset) and collection of blood samples for future genetic and biomarker analysis. Participants provide consent for longitudinal follow-up and enrolment in future cohort substudies. We also assess the acceptability of community-based echocardiographic examination and compare self-assessed quality of life between those with and without VHD.ConclusionsOxVALVE-PCS will provide contemporary epidemiological data concerning the community prevalence of undiagnosed VHD, facilitate accurate deployment of scarce resources to meet the anticipated increase in demand for VHD-associated healthcare and create a series of subcohorts with carefully defined genotypes and echocardiographic phenotypes for long overdue clinical studies.Ethics and disseminationThis study was approved by the local research ethics committee (Southampton, UK; REC Ref: 09/H0502/58).ResultsResults will be submitted for publication in peer-reviewed scientific journals.

show abstract

Section: Methods and Analysismentioning

confidence: 99%

The OxVALVE population cohort study (OxVALVE-PCS)—population screening for undiagnosed valvular heart disease in the elderly: study design and objectives

et al. 2014

View full text Add to dashboard Cite

show abstract

“…This has cemented CMR at the center of diagnostic imaging in Europe, proving that it is feasible and safe with 62% of the scans performed having an impact on patient management, the most common indication being for risk stratification in coronary artery disease. Florian Andre presented data from a cohort of more than a 1000 patients showing that measuring left ventricular ejection fraction by CMR reclassified many patients into different risk groups when compared to echocardiography [37]. Others have shown the potential clinical impact of more accurate measurement of ejection fraction by CMR on selecting patients who might benefit from defibrillator implantation [38].…”

Section: Implementation Of Cmr Into Routine Clinical Practicementioning

confidence: 99%

Highlights of the 16th annual scientific sessions of the Society for Cardiovascular Magnetic Resonance

Carpenter

Patel

Fernandes

2013

Journal of Cardiovascular Magnetic Resonance

View full text Add to dashboard Cite

The 16th Annual Scientific Sessions of the Society for Cardiovascular Magnetic Resonance (SCMR) took place in San Francisco, USA at the end of January 2013. With a faculty of experts from across the world, this congress provided a wealth of insight into cutting-edge research and technological development. This review article intends to provide a highlight of what represented the most significant advances in the field of cardiovascular magnetic resonance (CMR) during this year’s meeting.

show abstract

“…In the assessment of cardiac function, the current non-invasive gold standard is cardiovascular magnetic resonance (CMR) (Andre et al 2013). However, its expense, the requirement for trained personal and its lack of portability make it unsuitable for primary, home care and ambulatory scenarios.…”

Section: Introductionmentioning

confidence: 99%

Assessment of cardiovascular function from multi-Gaussian fitting of a finger photoplethysmogram

et al. 2015

View full text Add to dashboard Cite

Monitoring of cardiovascular function on a beat-to-beat basis is fundamental for protecting patients in different settings including emergency medicine and interventional cardiology, but still faces technical challenges and several limitations. In the present study, we propose a new method for the extraction of cardiovascular performance surrogates from analysis of the photoplethysmographic (PPG) signal alone.We propose using a multi-Gaussian (MG) model consisting of five Gaussian functions to decompose the PPG pulses into its main physiological components. From the analysis of these components, we aim to extract estimators of the left ventricular ejection time, blood pressure and vascular tone changes. Using a multi-derivative analysis of the components related with the systolic ejection, we investigate which are the characteristic points that best define the left ventricular ejection time (LVET). Six LVET estimates were compared with the echocardiographic LVET in a database comprising 68 healthy and cardiovascular diseased volunteers. The best LVET estimate achieved a low absolute error (15.41 ± 13.66 ms), and a high correlation (ρ = 0.78) with the echocardiographic reference.To assess the potential use of the temporal and morphological characteristics of the proposed MG model components as surrogates for blood pressure and vascular tone, six parameters have been investigated: the stiffness index (SI), the T1_d and T1_2 (defined as the time span between the MG model forward and reflected waves), the reflection index (RI), the R1_d and the R1_2 (defined as their amplitude ratio). Their association to reference values of blood pressure and total peripheral resistance was investigated in 43 volunteers exhibiting hemodynamic instability. A good correlation was found between the majority of the extracted and reference parameters, with an exception to R1_2 (amplitude ratio between the main forward wave and the first reflection wave), which correlated low with all the reference parameters. The highest correlation ([Formula: see text] = 0.45) was found between T1_2 and the total peripheral resistance index (TPRI); while in the patients that experienced syncope, the highest agreement ([Formula: see text] = 0.57) was found between SI and systolic blood pressure (SBP) and mean blood pressure (MBP).In conclusion, the presented method for the extraction of surrogates of cardiovascular performance might improve patient monitoring and warrants further investigation.

show abstract

Comparison of parameters for left ventricular volumes and function between echocardiography and cardiovascular magnetic resonance in a large group of cardiac patients

Cited by 3 publications

References 0 publications

The OxVALVE population cohort study (OxVALVE-PCS)—population screening for undiagnosed valvular heart disease in the elderly: study design and objectives

The OxVALVE population cohort study (OxVALVE-PCS)—population screening for undiagnosed valvular heart disease in the elderly: study design and objectives

Highlights of the 16th annual scientific sessions of the Society for Cardiovascular Magnetic Resonance

Assessment of cardiovascular function from multi-Gaussian fitting of a finger photoplethysmogram

Contact Info

Product

Resources

About