Comparison of Pain Control Method and Assessment on Postoperative Pain in Pediatric Urological Surgery of Penoscrotal and Inguinal Regions

Chung, Jae Min; Kim, Tae Nam; Lee, Kyong Mi; Baik, Seung Kug

doi:10.4111/kju.2007.48.2.163

Cited by 1 publication

(1 citation statement)

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“…In addition, lidocaine competes with bupivacaine at the sodium channel binding site, and blocks most of the binding of bupivacaine, which is the basis for suggesting that lidocaine be used to treat cardiac toxicity caused by bupivacaine [ 5 ]. We previously investigated the effect of bupivacaine and lidocaine on patients who underwent urologic surgery in the penoscrotal and inguinal regions [ 23 ].…”

Section: Discussionmentioning

confidence: 99%

The safety of a mixture of bupivacaine and lidocaine in children after urologic inguinal and scrotal surgery

Lee

Chung

2018

Investig Clin Urol

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PurposeLocal anesthetic agents such as bupivacaine and lidocaine are commonly used after surgery for pain control. The aim of this prospective study was to evaluate the safety of a mixture of bupivacaine and lidocaine in children who underwent urologic inguinal and scrotal surgery.Materials and MethodsFifty-five patients who underwent pediatric urologic outpatient surgeries, were prospectively enrolled in this study. The patients were divided into three groups according to age (group I: under 2 years, group II: between 3−4 years, and group III: 5 years and above). Patients were further sub-divided into unilateral and bilateral groups. All patients were injected with a mixture of 0.5% bupivacaine and 2% lidocaine (2:1 volume ratio) at the surgical site, just before the surgery ended. Hemodynamic and electrocardiographic parameters were measured before local anesthesia, 30 minutes after administration of local anesthesia, and 60 minutes after administration.ResultsThe patients' mean age was 40.5±39.9 months. All patients had normal hemodynamic and electrocardiographic parameters before local anesthesia, after 30 minutes, and after 60 minutes. Also, results of all intervals were within normal values, when analyzed by age and laterality. No mixture related adverse events (nausea, vomiting, pruritus, sedation, respiratory depression) or those related to electrocardiographic parameters (arrhythmias and asystole) were reported in any patients.ConclusionsA mixture of bupivacaine and lidocaine can be safely used in children undergoing urologic inguinal and scrotal surgery. An appropriate dose has no clinically significant hemodynamic or cardiac changes and adverse effects.

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Section: Discussionmentioning

confidence: 99%