Comparison of pain and extent of anesthesia in digital blocks for isolated finger lacerations: A randomized controlled trial

Jarragh, Ali; Lari, Ali; Burhamah, Waleed; Alherz, Mohammad; Nouri, Abdullah; Alshammari, Yahia; Al-Jasim, Ameer; AlRefai, Sulaiman; Alnusif, Naser

doi:10.4103/tjem.tjem_344_21

Cited by 1 publication

(2 citation statements)

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“…Once within the nerve, the RN picks up H+, and the subsequent RNH+ enters a sodium ion (Na+) channel to stymie nerve conduction. Until the body brings the pH of the cocktail into a more physiological range, the sedative will not take action (between 7.35 and 7.45) [ 5 ]. By raising the pH of the anesthetic solution, more of the anesthetic molecules will be in an uncharged state like RN negative ions, allowing them to enter nerve cells and produce anesthesia [ 6 ].…”

Section: Introductionmentioning

confidence: 99%

“…When there is contamination, the local pH drops, making it difficult for the standard sedative fluid to deliver effective and long-lasting pulpal drowsiness. Contaminated tissue is more acidic, increasing the difficulty of the RN change [ 5 ]. Most clinical experts believe that the sedative arrangement should cross the blood-nerve barrier and block the voltage-gated sodium channel to prevent depolarization of the nerve.…”

Section: Introductionmentioning

confidence: 99%

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A Comparative Study to Evaluate the Anesthetic Efficacy of Buffered Versus Non-buffered 2% Lidocaine During Inferior Alveolar Nerve Block

Jain¹,

Jha²,

Tiwari³

et al. 2022

Cureus

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Background: The study aimed to compare the clinical efficacy, safety, and acceptability of buffered lidocaine (8.4% sodium bicarbonate and 2% lidocaine with 1:80,000 adrenaline) versus non-buffered lidocaine (2% lidocaine with 1:80,000 adrenaline) during inferior alveolar nerve block.Materials and methods: Fifty patients who required bilateral extractions in a single arch were included in this study. One hundred extractions were carried out, and all of the patients had nerve blocks during the procedure. We also took note of the patient's pain level as measured on a visual analog scale, as well as the start of the action, duration of postoperative analgesia, and occurrence of any problems. The duration of anesthesia was assessed by the feeling of numbness and the first sign of pain.Result: All the patients in both study groups reported subjective numbness of the lips and tongue. The depth of anesthesia was evaluated by pain and comfort during the procedure with a visual analog scale and showed no significant difference between the two groups. The onset of action for the pterygomandibular nerve block was 1.240.31 minutes (buffered) and 1.710.51 minutes (non-buffered). When compared, the duration of anesthesia was 327.18102.98 minutes (buffered) and 129.0826.85 minutes (non-buffered).Conclusion: This study concludes that the buffered solution has a faster onset of action than the nonbuffered solution. Both solutions exhibit similar intraoperative efficacy. The duration of postoperative anesthesia was prolonged with buffering. Buffering also reduced pain scores during the early postoperative period.

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Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%