Comparison of myonuclear domain in phylogenetically paired tropical and temperate bird species

Jiménez, Ana Gabriela; Jesus, Aliyah D. De

doi:10.1111/jav.02880

Cited by 2 publications

(1 citation statement)

References 67 publications

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“…Thus, the control group of sparrows should have higher numbers of nuclei, compared with the heat-shocked and recovery group, as their winter phenotype pectoralis muscle should have undergone hypertrophic accretion, similar to fast-growing quail, suggesting a similar physiological mechanism of control. Additionally, tropical bird species (exposed to a thermally stable warm climate) had more nuclei per mm of muscle fiber compared with their temperate counterparts, but no differences in MND (Jimenez and De Jesus 2021b).…”

Section: Myonuclear Domain and Muscle Remodeling In Birds With Respec...mentioning

confidence: 94%

Skeletal muscle and metabolic flexibility in response to changing energy demands in wild birds

2022

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Phenotypically plastic responses of animals to adjust to environmental variation are pervasive. Reversible plasticity (i.e., phenotypic flexibility), where adult phenotypes can be reversibly altered according to prevailing environmental conditions, allow for better matching of phenotypes to the environment and can generate fitness benefits but may also be associated with costs that trade-off with capacity for flexibility. Here, we review the literature on avian metabolic and muscle plasticity in response to season, temperature, migration and experimental manipulation of flight costs, and employ an integrative approach to explore the phenotypic flexibility of metabolic rates and skeletal muscle in wild birds. Basal (minimum maintenance metabolic rate) and summit (maximum cold-induced metabolic rate) metabolic rates are flexible traits in birds, typically increasing with increasing energy demands. Because skeletal muscles are important for energy use at the organismal level, especially to maximum rates of energy use during exercise or shivering thermogenesis, we consider flexibility of skeletal muscle at the tissue and ultrastructural levels in response to variations in the thermal environment and in workloads due to flight exercise. We also examine two major muscle remodeling regulatory pathways: myostatin and insulin-like growth factor -1 (IGF-1). Changes in myostatin and IGF-1 pathways are sometimes, but not always, regulated in a manner consistent with metabolic rate and muscle mass flexibility in response to changing energy demands in wild birds, but few studies have examined such variation so additional study is needed to fully understand roles for these pathways in regulating metabolic flexibility in birds. Muscle ultrastrutural variation in terms of muscle fiber diameter and associated myonuclear domain (MND) in birds is plastic and highly responsive to thermal variation and increases in workload, however, only a few studies have examined ultrastructural flexibility in avian muscle. Additionally, the relationship between myostatin, IGF-1, and satellite cell (SC) proliferation as it relates to avian muscle flexibility has not been addressed in birds and represents a promising avenue for future study.

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Section: Myonuclear Domain and Muscle Remodeling In Birds With Respec...mentioning

confidence: 94%

Skeletal muscle and metabolic flexibility in response to changing energy demands in wild birds

2022

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Lack of variation in nuclear DNA content in avian muscle

Jiménez

Lencyk

2022

Genome

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The avian pectoralis muscle demonstrates plasticity with regard to size, so that temperate birds facing winter conditions or birds enduring a migration bout tend to have significant increases in the size and mass of this tissue due to muscular hypertrophy. Myonuclear domain (MND), the volume of cytoplasm a myonuclei services, in the pectoralis muscle of birds seems to be altered during thermal stress or changing seasons. However, there is no information available regarding muscle DNA content or ploidy level within the avian pectoralis. Changes in muscle DNA content can be used in this tissue to aid in size and mass changes. Here, we hypothesized that long-distance migrants or temperate residents would use the process of endoreduplication to aid in altering muscle size. Mostly contradictory to our hypotheses, we found no differences in the mean muscle DNA content in any of the 62 species of birds examined in this study. We also found no correlations between mean muscle DNA content and other muscle structural measurements, such as the number of nuclei per millimeter of fiber, myonuclear domain, and fiber cross-sectional area. Thus, while avian muscle seems more phenotypically plastic than mammalian muscle, the biological processes surrounding myonuclear function may be more closely related to those seen in mammals.

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Comparison of myonuclear domain in phylogenetically paired tropical and temperate bird species

Cited by 2 publications

References 67 publications

Skeletal muscle and metabolic flexibility in response to changing energy demands in wild birds

Skeletal muscle and metabolic flexibility in response to changing energy demands in wild birds

Lack of variation in nuclear DNA content in avian muscle

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