Comparison of Midazolam and Ketamine as Oral premedicants in pediatric patients

Remadevi, R; Ezhilarasu, Punitha; Chandrasekar, LJ; Vasudevan, Anupama

doi:10.5580/22e4

Cited by 1 publication

(2 citation statements)

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“…The ideal premedication in children should be readily accepted by children, with rapid and reliable onset, provide anxiolysis with sedative effect, and have minimal side effects with, rapid elimination to facilitate rapid recovery for early discharge. Earlier studies have indicated that both oral Midazolam and oral Ketamine fulfill many of these characteristics, and both may be useful premedicants in pediatric anesthesia [6].…”

Section: Discussionmentioning

confidence: 99%

“…Midazolam, with its rapid onset and relatively short duration of action, has proven to be a useful premedication to decrease preoperative anxiety and facilitate separation from parents with fewer unwanted side effects [5]. Several studies suggested that different doses of oral ketamine is a better than oral Midazolam 0.5mg/kg in providing sedation and anxiolysis in children with minimal side effects [6,7] children receiving high dose of Ketamine may experience nystagmus or vomiting [8]. Therefore, a relatively low dose ketamine was selected in the current study to overcome its side effects if given in high doses.…”

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confidence: 99%

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Supplementary Low - Dose Oral Ketamine Provides Better Parental Separation and Face Mask Acceptance

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2014

Int J Anesthetic Anesthesiol

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One of the challenges for pediatric anesthetists is to minimize the child and parents stress at induction of anesthesia. A wide range of techniques has been used, including education of the child and family, as almost 50% of these children become anxious in the perioperative period. Children are principally worried about pain and separation from their parents. Up to 60% of children undergoing routine outpatient surgery present at two weeks, postoperatively, with new onset behavioral disturbances such as anxiety, nighttime crying, enuresis, and sleep or eating disturbances. It is generally agreed that behavioral, non-pharmacological techniques help in reducing the incidence of these delayed sequaelae. These techniques include the use of music, stories, and flavored face masks. Psychological preparation of the child and the family in the preoperative visit is more important

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Section: Discussionmentioning

confidence: 99%

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confidence: 99%