Comparison of Metocurine and Pancuronium—Myocardial Tension-Time Index during Endotracheal Intubation

J, Basta; Lichtiger, Monte

doi:10.1097/00000542-197705000-00017

Cited by 6 publications

(1 citation statement)

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“…In spite of the large doses of myoneural blocking drugs used, no attenuation was observed in circulatory response (RPP) to tracheal intubation in the metocurine group as compared with the pancuronium group. This finding seems to differ from that of Basta and Lichtiger (1977), who compared the effects of metocurine and pancuronium on changes in the tension-time index (TTI) evoked by endotracheal intubation in patients with coronary artery disease and anaesthetized with halothanenitrous oxide. TTI after intubation was significantly greater in their pancuronium group and 18% of the patients given pancuronium showed ST segment depression.…”

Section: Pancuroniumcontrasting

confidence: 61%

Comparison of Haemodynamic Effects of Metocurine and Pancuronium in Patients With Coronary Artery Disease

Heinonen

Yrjölä

1980

British Journal of Anaesthesia

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The haemodynamic effects of large bolus doses of metocurine 0.45 mg kg-1 and pancuronium 0.1 mg kg-1 were compared in patients with coronary artery disease anaesthetized with diazepam, anileridine and nitrous oxide. Hypotension occurred more frequently after metocurine and was a result of a decrease in systemic vascular resistance. After pancuronium there was no increase in arterial pressure or heart rate, but a small increase in cardiac index. The decrease in heart rate after metocurine was the principal cause of the statistically significant difference in cardiac index between the two groups. Contrary to previous findings, metocurine did not attenuate circulatory responses to tracheal intubation. During surgical stimulation, two of the 10 patients of the pancuronium group developed significant ST segment depression and three patients had a rate-pressure product greater than 12 000 mm Hg beat min-1. However, the difference in rate-pressure product between the groups was not statistically significant.

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Section: Pancuroniumcontrasting

confidence: 61%