Comparison of Methods of Endotamponade Used During 23-Gauge Pars Plana Vitrectomy and the Risk of Raised Intraocular Pressure During 24-Month Follow-Up: A Retrospective Study of 196 Patients

Abstract

Departmental sources Background: Pars plana vitrectomy (PPV) is used to treat retinal conditions, including retinal detachment, and involves removal of the vitreous gel from the eye. Complications following PPV include raised intraocular pressure (IOP). This retrospective study aimed to compare methods of endotamponade used during 23-gauge PPV and the risk of raised IOP during 24-month follow-up at a single center. Material/Methods: The study included 196 patients (age, 15-86 years; mean, 63.5 years) (196 eyeballs). There were 93 patients (47.45%) with a preoperative history of type 2 diabetes mellitus and 14 patients (7.14%) with a history of myopia. IOP was measured with Goldmann applanation tonometry at one-, three-, six-, 12-, and 24-month follow-up. The outcome was compared following endotamponade with silicone oil, sulfur hexafluoride (SF6), and balanced salt solution (BSS). Results: Mean IOP at one-month follow-up was 17.2 mmHg (±3.61 mmHg; range, 9-45 mmHg), and at 24-month follow-up was 17.3 mmHg (±3.23 mmHg; range, 7-30 mmHg). IOP following PPV was significantly associated with the indication for PPV (P=0.023), and the type of endotamponade used (P=0.049). In patients with silicone oil endotamponade, the risk of IOP at 24 months was increased by 2.3 times compared with SF6 or BSS endotamponade. Patients with SF6 endotamponade had a risk of IOP that was 3.3 times lower than for silicone oil tamponade or BSS tamponade. Conclusions: Silicone oil endotamponade in PPV was associated with an increased risk of IOP at 24-month follow-up.

Complications associated with the use of silicone oil in vitreoretinal surgery: A systemic review and meta‐analysis

“…2017; Lyssek‐Boroń et al. 2019; Yaşa & Alkın 2018; Davis et al. 1995; Valone & McCarthy 1994; Oh et al.…”

“…2019; Lyssek‐Boroń et al. 2019); in 634 patients (634 eyes) from nine articles, the eye was filled with SO or heavy SO (Wong et al. 2009; Romano et al.…”

“…2018; Lyssek‐Boroń et al. 2019; Murat n.d.). The mean duration follow‐up time after surgery was 15.47 ± 13.52 months (median: 12; range: [1–120]).…”

“…2018; Lyssek‐Boroń et al. 2019; Murat n.d.), and it was 4.35 ± 3 months (median: 3.15 months; range 2–45.98). The 54.67% ( n = 1461) of the eyes included in the meta‐analysis were phakic, 968 were pseudophakic (36.22%) and 243 aphakic (9.09%); however, 18 studies did not provide this information (Hammer et al.…”

Assessment of Vascular Changes in Patients after Pars Plana Vitrectomy Surgery Due to Macula-Off Rhegmatogenous Retinal Detachment

“…In the remaining eyes, however, an artificial lens was implanted during the PPV procedure. Two types of endotamponade were used depending on the intraoperative evaluation, i.e., silicone oil (removed 1–1.5 months after PPV) in 80 eyes and 20% SF6 in 34 eyes [ 26 , 27 ]. Each patient underwent a complete ophthalmologic examination, including best corrected visual acuity testing using Snellen charts, slit lamp examination and OCT-A, 9 ± 2 months (median 10 months; range 6–17 months) after the operation.…”