Comparison of Male and Female Sexual Dysfunction between Hemodialysis and Peritoneal Dialysis in Patients with End-Stage Renal Disease: An Analytical Cross-Sectional Study

Abstract

Background. Maintenance dialysis is the most common treatment for end-stage renal disease (ESRD) patients. One of the most ignored but important health issue among dialysis patients is sexual dysfunction, which interferes with quality of life (QoL). Studies showed that the side effects of the two conventional methods of dialysis (hemodialysis (HD) and peritoneal dialysis (PD)) are different on a patient’s health. Therefore, we sought to compare the sexual dysfunction score, both male and female, between patients undergoing HD and PD. Methods. One hundred seventy adults (85 HD and 85 PD) subject with end-stage renal disease (ESRD) on dialysis for at least 2 months were included. For male subjects, the erectile function (EF) domain of the International Index of Erectile Function (IIEF) questionnaire was calculated. Moreover, the Female Sexual Function Index (FSFI) questionnaire was calculated for females. Data were analyzed via SPSS software. Two independent sample t-test with two-sided significance level of 5% was used for comparing the sexual dysfunction score between HD and PD patients. Results. Out of 170 patients with mean age of 49.34 ± 11.7 years, 52.9% were female. Better sexual function scores were obtained in the HD group’s females for desire, orgasm, and satisfaction domains, as well as the total score ( P = 0.03, 0.016, 0.02, and 0.039, respectively). The erectile function was significantly better in the PD group’s males ( P ). Conclusion. We found better sexual life in the HD group’s females and PD group’s males. Considering dialysis as a life-long treatment of CKD patients, this part of a patient’s life must be taken seriously by the healthcare providers to choose the most suitable method for patients based on their personalized conditions.

Sexual Dysfunction in Female Patients Undergoing Hemodialysis and Its Relationship With Anxiety and Depression

“…It is multidimensional and affected by various physical, psychological, and social factors. This finding is supported by other studies as well [ 7 , 16 ]. Moreover, some authors described pain as the least common problem [ 18 , 19 ].…”

“…In our study, hypertension was the most common comorbidity (56.4%) in chronic kidney disease (CKD) patients. Hypertension was also the most common risk factor as found by Strippoli et [16]. This is because hypertension is the most commonly prevalent comorbidity in the general population (30%) [17].…”

Coping strategies and its relationship with sexual dysfunction in adults receiving haemodialysis and peritoneal dialysis: A cross‐sectional study

“…Among these studies, one study conducted by Zeighami et al. (2022) showed that female adults receiving HD had better sexual function than the PD group, and that the male adults receiving PD had better sexual function than the HD group (Zeighami et al., 2022). In other studies, some reported adults receiving HD had more sexual problems than PD, while others reported adults receiving PD had more sexual problems than HD (Almutary et al., 2016; Basok et al., 2009; Toorians et al., 1997).…”

“…Haemodialysis (HD) and peritoneal dialysis (PD) are commonly used renal replacement therapies for end‐stage renal disease (ESRD) (Zeighami et al., 2022). Adults receiving HD and PD face several physiological, psychological and social problems (Vélez‐Vélez & Bosch, 2016).…”

“…Sexual dysfunction is associated with hormonal, neural, vascular and psychosocial causes in individuals with ESRD (Johansen, 2020). Additionally, medications and other comorbid diseases such as vascular and neurological diseases are common causes of sexual dysfunction in ESRD (Zeighami et al., 2022). Unfortunately, sexual dysfunction causes anxiety, social isolation and poor quality of life in adults receiving dialysis (Chou et al., 2021; Pyrgidis et al., 2021).…”