Comparison of Macular Thickness Measurements between Time Domain and Spectral Domain Optical Coherence Tomography

Abstract

Although both time domain and spectral domain OCTs are reliable for macular thickness measurements, spectral domain OCT has better measurement repeatability compared with time domain OCT. Macular measurements obtained from the two OCT systems may not be used interchangeably.

Comparison of time domain Stratus OCT and spectral domain SLO/OCT for assessment of macular thickness and volume

“…The ratio between MT measured with SD-SLO/OCT and TD-OCT was 1.1, whereas it has resulted to be 1.01 in case of a different SD-OCT device. 13 However, our data show that the different OCT acquisition systems determine different retinal thickness measurements but scarcely influence retinal volume measurements.…”

“…The poor agreement between Stratus OCT and a different spectral domain OCT (3D OCT, Topcon, Tokyo, Japan) has already been reported. 13 Although this was limited to normal eyes, it resulted in a SD-OCT/ TD-OCT ratio of 1.01 and a correlation between the amount of difference and the thickness was not suggested. To obtain retinal thickness measurement, Stratus OCT uses segmentation algorithms to mark the ILM as the inner boundary and the inner segment/outer segment junction (IS/OS) as the outer boundary.…”

“…A better repeatability of measurement compared with Stratus OCT has been reported for spectral domain OCT in healthy eyes. 13,14 The presence of both time domain and spectral domain OCT systems in ophthalmic practices is becoming increasingly widespread, and the several SD-OCT devices introduced to clinical practice use different algorithms to calculate retinal thickness. This is the first study where an evaluation of the artefacts and a comparison of retinal thickness and volume measurements obtained with both Stratus TD-OCT and OTI (Ophthalmic Technologies Inc., Canada) SD-OCT were performed in normal and pathologic eyes.…”

Spectral- and time-domain optical coherence tomography measurements of macular thickness in normal eyes and in eyes with diabetic macular edema

“…Leung et al 12 reported the 95% limits of agreement between Stratus and 3D-OCT to be 3.9-37.8 mm. Such poor agreements are considered too large to allow devices to be used interchangeably.…”

Results of Phacoemulsification Surgery in Diabetic and Non-Diabetic Patient groups

“…Günümüzde küçük kesili modern katarakt ameliyatına rağmen diyabetik hastalarda, ameliyat sonrası dönemde maküla değişiklikleri görülmektedir. [4][5][6] Otani ve ark. [7] santral maküler kalınlık ile en iyi düzel-tilmiş görme keskinliği arasında negatif ve zayıf bir korelasyon olduğunu saptamışlardır.…”