Comparison of Low Cardiac Output Syndrome After Pda Ligation and Transcatheter Pda Closure in Extremely Low Birth Weight Infants

Philip, Ranjit; Waller, B. Rush; Chilakala, Sandeep; Apalodimas, Leah; Sathanandam, Shyam

doi:10.1016/s0735-1097(19)31183-0

Cited by 5 publications

(1 citation statement)

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“…Signs of a low cardiac output state include hypotension, increased metabolic acidosis and respiratory failure ( 142 , 143 ). Studies have found a significantly lower incidence of post-ligation syndrome in ELBW infants who underwent transcatheter PDA closure compared to surgical ligation ( 144 – 146 ). Jain demonstrated that prophylactic milrinone administration reduced the incidence of post-ligation syndrome from 44 to 11% in high-risk patients ( 147 ).…”

Section: Post-ligation Syndromementioning

confidence: 99%

Management of Patent Ductus Arteriosus in Premature Infants in 2020

et al. 2021

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The patent ductus arteriosus (PDA) is the most commonly found cardiac condition in neonates. While there have been several studies and thousands of publications on the topic, the decision to treat the PDA is still strongly debated among cardiologists, surgeons, and neonatologists. This is in part due to the shortage of long-term benefits with the interventions studied. Practice variations still exist within sub-specialties and centers. This article briefly summarizes the history, embryology and histology of the PDA. It also succinctly discusses the hemodynamic significance of a PDA which builds the framework to review all the available literature on PDA closure in premature infants, though not a paradigm shift just yet; it introduces transcatheter PDA closure (TCPC) as a possible armament to the clinician for this age-old problem.

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