Comparison of Logistic Regression and Machine Learning Methods for Predicting Postoperative Delirium in Elderly Patients: A Retrospective Study

Song, Yuxiang; Yang, Xiaodong; Luo, Yungen; Ouyang, Chun‐lei; Yu, Yanxia; Ma, Yulong; Li, Hao; Lou, Jingsheng; Liu, Yanhong; Chen, Yiqiang; Cao, Jiangbei; Mi, Weidong

doi:10.2139/ssrn.4123191

Cited by 2 publications

(1 citation statement)

References 0 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The study included patients who had undergone surgery for intertrochanteric fractures at the Chinese PLA General Hospital between January 2014 and December 2017. The criteria for inclusion were as follows: patients were 65 years of age or more [9,13] and underwent surgery for intertrochanteric fractures. The criteria for exclusion were as follows: patients had multiple fractures or trauma; had missing data or were lost to follow-up.…”

Section: Study Design and Patientsmentioning

confidence: 99%

The Modified Lymphocyte C-reactive Protein Score is a Promising Indicator for Predicting 3-year Mortality in Elderly Patients with Intertrochanteric Fractures

Zhang²,

Ran

et al. 2022

Preprint

Self Cite

View full text Add to dashboard Cite

Background Hip fractures are common in elderly patients, and almost all the patients undergo surgery. This study aimed to develop a novel modified lymphocyte C-reactive protein (CRP) score (mLCS) to simply and conveniently predict 3-year mortality in elderly patients undergoing intertrochanteric fracture surgery. Methods A retrospective study was conducted on elderly patients who underwent intertrochanteric fracture surgery between January 2014 and December 2017. The mLCS was developed according to the value of CRP and lymphocyte counts. Univariate and multivariate Cox regression analyses were used to identify independent risk factors for 3-year mortality after surgery. The performances of the lymphocyte CRP score (LCS) and mLCS to predict 3-year mortality were then compared using C-statistics, decision curve analysis (DCA), net reclassification index (NRI) and integrated discrimination improvement (IDI). Results A total of 291 patients were enrolled, of whom 52 (17.9%) died within 3 years after surgery. In the multivariate Cox regression analysis, mLCS (hazard ratio (HR), 5.415; 95% confidence interval (CI), 1.743–16.822; P = 0.003) was significantly associated with postoperative 3-year mortality. The C-statistics of LCS and mLCS for predicting 3-year mortality were 0.644 and 0.686, respectively. The NRI (mLCS vs. LCS, 0.018) and IDI (mLCS vs. LCS, 0.017) indicated that the mLCS performed better than the LCS. DCA also showed that mLCS had a higher clinical net benefit. Conclusions mLCS is a promising predictor that can simply and conveniently predict 3-year mortality in elderly patients undergoing intertrochanteric fracture surgery.

show abstract

Section: Study Design and Patientsmentioning

confidence: 99%