Comparison of lipid peroxidation and catalase response in invasive dreissenid mussels exposed to single and multiple stressors

Abstract

Dreissenid mussels Dreissena bugensis (quagga mussel) and Dreissena polymorpha (zebra mussel) are prolific invasive species to the freshwaters of the United States and Western Europe. In the Great Lakes, D. polymorpha has initially dominated the system since its invasion in the mid-1980s; however, recently D. bugensis has displaced D. polymorpha as the dominant species. Dreissena bugensis has several competitive advantages over D. polymorpha, including greater tolerances to deeper and colder waters and lower respiration rates. Nevertheless, physiological differences between the species remain largely unknown. The oxidative stress response is a mechanism used by all organisms to mitigate environmental stress by reducing oxygen radicals in the body, and comparing this mechanism between similar species can be useful for understanding how different species compete in aquatic environments. We compared oxidative stress biomarkers (lipid peroxidation [LPO] and catalase [CAT] activity) in mussels after exposure to 4 stressors (i.e., high densities, temperature, hypoxia, and polychlorinated biphenyls [PCBs]) independently and in combinations of 2 stressors. Overall, D. bugensis had lower LPO and CAT activity than D. polymorpha when exposed to single stressors; however, in multiple stressor treatments D. bugensis had increased LPO, especially with high temperatures and PCBs. The lower lipid damage in D. bugensis compared with D. polymorpha under single stressor conditions may come at the cost of the ability to respond to multiple stressors. Environ Toxicol Chem 2018;37:1643-1654. © 2018 SETAC.

The Effect of Ellagic Acid on Hepatic Lipid Metabolism and Antioxidant Activity in Mice

“…Lipid peroxidation resulting from oxidative stress produces a large amount of MDA, which can also contribute to hepatocyte damage, thereby aggravating the lesions (Tsikas, 2017). By contrast, SOD and CAT are important antioxidant enzymes, responsible for scavenging free radicals and inhibiting lipid peroxidation, thus protecting the hepatocytes against toxicity (Mansuroğlu et al, 2015;Nowicki and Kashian, 2018). A kinetic DFT study found that EA was more reactive toward HO•, but less reactive toward CCl 3 OO• with good rate constants for the reactions (Tošović and Bren, 2020).…”

Molecular Mechanisms Involved in Oxidative Stress-Associated Liver Injury Induced by Chinese Herbal Medicine: An Experimental Evidence-Based Literature Review and Network Pharmacology Study

“…H 2 O 2 is decomposed into H 2 O and O 2 by the action of CAT and GPx. In this process, CAT is an enzyme that can be found in almost all aerobiotic organs [ 27 ], whereas GPx enzymes transform H 2 O 2 by using it to oxidize reduced GSH into oxidized glutathione (GSSG). GR, a flavoprotein (FAD-containing) enzyme, regenerates GSH from GSSG with the reducing power of nicotinamide adenine dinucleotide phosphate oxidase (NAD(P)H) [ 28 , 29 ].…”

Identification of Optimal Calcium and Temperature Conditions for Quagga Mussel Filtration Rates as a Potential Predictor of Invasion

“…It is an essential ion required for shell growth and physiological functions in dreissenid species (Cohen and Weinstein ; Whittier et al ); however, most of the research on the impact of calcium on dreissenid species has been focused on zebra mussels, not quagga mussels. Although quagga mussels are in the same family as zebra mussels, there are notable differences in colonization patterns, temperature and oxygen tolerances, growth, shell mass, and oxidative stress response (Stoeckmann ; Casper and Johnson ; Nowicki and Kashian ). Similarly, the difference in the distribution of zebra and quagga mussels is highly influenced by calcium concentrations (Zhulidov et al ; Jones and Ricciardi ).…”

“…The initial rapid dispersal of zebra mussels compared to quagga mussels may in part be due to the differences in the byssal thread secretion rate and the strength of attachment to vectors that facilitate transport such as recreational boats, anchors, propellers, and boat trailers (Dermott and Munawar ; Claxton and Mackie ; Peyer et al ). In addition, differences in depth preferences (Nalepa et al ; Karatayev et al ), temperature changes (Mitchell et al ), oxidative stress levels (Nowicki and Kashian ) and habitat preference, and differences in filtration rates (Diggins ) may provide different habitat preferences for the 2 species. Because zebra mussels have been established as invasive species longer than quagga mussels, the majority of the existing literature focuses on zebra mussels.…”