Comparison of Invasive and Non-Invasive Tests Diagnosis and Monitoring of Helicobacter Pylori Infection in Children

Bayan, Hino; Eliakim, Rami; Levine, Arie; Sprecher, Hannah; Berkowitz, Donald; Hartman, Christina; Eshach-Adiv, Orly; Shamir, Raanan

doi:10.1097/00005176-200411000-00013

Cited by 53 publications

(49 citation statements)

References 36 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The stool antigen test is preferable because it is simple, cheap and comparable to the urea breath test [46,47,48]. If the stool antigen test is positive, eradication treatment may resolve thrombocytopenia and should be considered.…”

Section: Resultsmentioning

confidence: 99%

Management of Chronic Childhood Immune Thrombocytopenic Purpura: AIEOP Consensus Guidelines

et al. 2009

View full text Add to dashboard Cite

Background/Objective: The management of chronic childhood idiopathic thrombocytopenic purpura (ITP) is distinct from acute ITP. Similar to the publication on acute ITP guidelines, the AIEOP (Associazione Italiana di Ematologia e Oncologia Pediatrica) considered it appropriate to develop consensus guidelines for chronic childhood ITP to provide useful and shared information for physicians, healthcare professionals, parents and patients. Design/Methods: A preliminary, evidence-based document issued by a select group of AIEOP pediatric hematologists was discussed, modified and approved during a Consensus Conference according to procedures previously validated by the AIEOP Board. Results: The guidelines give prominence to the periodical reevaluation of all the etiological hypotheses of thrombocytopenia in relation to its clinical condition. The majority of chronic ITP children do not require treatment, especially if bleeding is absent or minimal. The treatment decision depends on several factors other than the platelet count, and treatment options are suggested in relation to the therapeutic scenarios. Recommendations are given regarding support for surgery, particular hemorrhagic conditions, daily activities/sports, as well as for vaccines and drugs. Experimental treatments are also discussed.

show abstract

Section: Resultsmentioning

confidence: 99%

Management of Chronic Childhood Immune Thrombocytopenic Purpura: AIEOP Consensus Guidelines

et al. 2009

View full text Add to dashboard Cite

show abstract

“…In this previous study, there were 4.5% of inconclusive results (gray zone), which is similar to the reported on the present study. Recently, it has been developed a new monoclonal stool antigen test, which is at least as accurate as HpSA (97.5% sensitivity and 94.7% specificity) and did not have any gray zone (6).…”

mentioning

confidence: 99%

Low Prevalence of Helicobacter pylori infection evaluated by stool antigen test in preschool and school children

Portorreal¹,

Machado²,

Vigliar³

et al. 2008

Braz. J. Microbiol.

View full text Add to dashboard Cite

show abstract

“…Firstly, it should be mentioned that serological tests are not useful to diagnose active H. pylori infection or monitor eradication therapy (25). In fact, histological examination is the most accurate method to diagnose H. pylori infection in children, although this procedure is invasive and not pleasant and acceptable by children and their families (26).…”

Section: Definite Diagnosis Of Helicobacter Pylori In Children and MImentioning

confidence: 99%

“…Some use polyclonal antibodies which are highly sensitive and specific for the diagnosis of this infection in adults and children. A few studies on children found comparable efficacy between UBT and HpSA (25). Limitations of the HpSA include inter-test and lot-to-lot variability, cutoff values and lower accuracy after eradication therapy.…”

Section: Definite Diagnosis Of Helicobacter Pylori In Children and MImentioning

confidence: 99%

See 1 more Smart Citation

Gastrointestinal Complaints and Treatment of Helicobacter pylori in Children: A Narrative Review

Shahmirzadi¹,

Ghasemi-Kebria²,

Roshandel³

2016

J Pediatr Rev

View full text Add to dashboard Cite

Context: The role of Helicobacter pylori infection in children's problems is considered in recent years. Helicobacter pylori, a gram negative spiral flagellate organism has diverse effects and consequences on children's health, but in some issues especially in chronic abdominal pain its role continues to debate. The prevalence of H. pylori infection and remedial measures against it in Iranian children is increasing. Evidence Acquisition: Diagnostic tests are divided into two categories: Invasive and noninvasive. Diagnostic methods are available and although invasive methods are more accurate and reliable; non-invasive methods are more acceptable and practical for children. Serological diagnosis assays are not worth much in the pediatric fields. Results: It is important to emphasize that diagnostic methods for H. pylori are revised and in some conditions, such as chronic abdominal pain, contrary to the impression, no treatment is required. Conclusions: Triple therapy is a reasonable method to eradicate H. pylori in the first stage, but different combinations and one week courses in the Iranian studies were successful.

show abstract

Comparison of Invasive and Non-Invasive Tests Diagnosis and Monitoring of Helicobacter Pylori Infection in Children

Abstract: Stool antigen (FemtoLab) and UBT were equally effective in diagnosing and confirming eradication of H. pylori infection in children.

Cited by 53 publications

References 36 publications

Management of Chronic Childhood Immune Thrombocytopenic Purpura: AIEOP Consensus Guidelines

Management of Chronic Childhood Immune Thrombocytopenic Purpura: AIEOP Consensus Guidelines

Low Prevalence of Helicobacter pylori infection evaluated by stool antigen test in preschool and school children

Gastrointestinal Complaints and Treatment of Helicobacter pylori in Children: A Narrative Review

Contact Info

Product

Resources

About