Comparison of Intravenous Oxytocin and Prostaglandin E2 for Accelerating Labour

Abstract

SummaryIn a prospective study of 52 consecutive women who required acceleration of labour intravenous prostaglandin E2 (PGE,) was used as the oxytocic agent. These mothers were matched for age, parity, height, gestational age, initial cervical dilatation, and station and position of the fetal head with 52 women whose labours were accelerated with oxytocin; both drugs were equally effective. Acceleration to delivery intervals, second-stage durations, the number of assisted deliveries, and Apgar scores were similar regardless of the oxytocic used.Although PGE2 compares well with oxytocin, it offers no further advantages and is more expensive and less well tried than oxytocin.

A Comparative Study of Labor Induced by Oral Prostaglandin E2 and Buccal Tablets of Demoxytocin

“…The success rate of induction was high in both groups. However, a difference in favor of PGE 2 was found, which is in agreement with other reports (9).…”

Comparative trial of extra-amniotic and vaginal prostaglandin E2in tylose gel for induction of labor

“…Significant benefits have been demonstrated for the induction of abortion and the induction of labor when the cervix is unfavourable [12,14]. When the cervix is favourable, prostaglandins alone have not been shown to have significant advantages over surgical induction and Syntocinon and are associated with a high incidence of gastrointestinal side effects [6,15], However, surgical induction is not without problems. When the cervix is unripe, artifical rupture of the membranes (ARM) may be difficult and labor may be long or fail to become established.…”