Comparison of Iliac Bone Transplantation with Bone Transport in the Treatment of Femur Fracture and Bone Defect

Abstract

Objective. To compare the curative effect of iliac bone transplantation with the bone transport in the treatment of femur fracture complicated with a bone defect. Methods. Patients with femur fractures and defects who were admitted to our hospital from January 1, 2020, to January 31, 2022, and met the inclusion criteria were retrospectively selected and allocated into an iliac bone transplantation group or a bone transport group. The treatment effect and quality of life of the two groups were compared. Results. A total of 98 patients who met the inclusion standards were enrolled, including 50 cases in the iliac bone transplantation group and 48 cases in the bone transport group. There were no significant differences in IL-6, IL-8, TNF-α, visual analog scale (VAS) score, or Japanese Orthopedic Association (JOA) score between the two groups on postsurgical day 1 ( p = 0.051 , 0.150, 0.102, 0.564, and 0.826 respectively), but there were significant differences in the above index on postsurgical day 7 (all p < 0.01 ). There were no significant differences in social function, physical function, role function, and cognitive function between the two groups one week after the operation ( p = 0.245 , 0.051, 0.102, and 0.067, respectively), but there were significant differences in the above parameters at one month after operation ( p = 0.001 , 0.005, 0.005, and 0.001, respectively). The total effective rate of the bone transplantation group was significantly better than that of the iliac bone transplantation group ( p = 0.026 ). The number of postoperative complications in the bone removal group was significantly fewer than that of the iliac bone graft group ( p = 0.001 ). Conclusion. Bone transport is effective in treating femur fractures complicated with bone defects, with fewer postoperative complications.

Biomimetic composite hydrogel promotes new bone formation in rat bone defects through regulation of miR-19b-3p/WWP1 axis by loaded extracellular vesicles

“…Soak the Gel-OCS/MBGNs@EVs in a 15 mL centrifuge tube containing 4 mL of PBS. At different time points (1,3,6,9,12,15,18, and 21 days), 100 μL of supernatant was replaced with 100 μL of fresh PBS. The concentration of EVs in the supernatant was evaluated by detecting the fluorescence intensity of DiR (Ex: 754 nm, Em: 778 nm) in the supernatant.…”

“…The use of bone transplantation utilizes the principle of "tension-stress law". During the puncture process outside the body, the steel nail is fixed on the bone in the fracture area, and the bone is gradually lengthened by bone cutting [1]. During this process, both elongation and compression regions benefit the formation of calli until the bone defect is healed [2,3].…”

“…During this process, both elongation and compression regions benefit the formation of calli until the bone defect is healed [2,3]. Although bone transplantation surgery has the advantages of simple operation, small trauma, and fast bone repair, its surgical operation is complex, and the incidence of complications is high [1,4].…”

Retracted: Comparison of Iliac Bone Transplantation with Bone Transport in the Treatment of Femur Fracture and Bone Defect

“…This article has been retracted by Hindawi following an investigation undertaken by the publisher [ 1 ]. This investigation has uncovered evidence of one or more of the following indicators of systematic manipulation of the publication process: Discrepancies in scope Discrepancies in the description of the research reported Discrepancies between the availability of data and the research described Inappropriate citations Incoherent, meaningless and/or irrelevant content included in the article Peer-review manipulation …”

“…Tis article has been retracted by Hindawi following an investigation undertaken by the publisher [1]. Tis investigation has uncovered evidence of one or more of the following indicators of systematic manipulation of the publication process:…”