Abstract:This communication describes an exercise in quantitative human pharmacology having characteristics uncommon in clinical trials: measurement of those effects for which the drug is intended;
“…In Fig. 13, the weak diuretic (chlorothiazide) 13 cleared 152 the first 40 lb of edema, but it required the strong diuretic (meralluride) to clear the last 10 lb.…”
Section: Magnitude Of Initial Diuresis Us Reactive Antidiuresismentioning
“…In Fig. 13, the weak diuretic (chlorothiazide) 13 cleared 152 the first 40 lb of edema, but it required the strong diuretic (meralluride) to clear the last 10 lb.…”
Section: Magnitude Of Initial Diuresis Us Reactive Antidiuresismentioning
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