Comparison of Hospital Mortality With Intra-Aortic Balloon Counterpulsation Insertion Before Versus After Primary Percutaneous Coronary Intervention for Cardiogenic Shock Complicating Acute Myocardial Infarction

Abdel‐Wahab, Mohamed; Saad, Mohammed; J, Kynast; Geist, Volker; Sherif, Mohammad; Richardt, Gert; Töelg, Ralph

doi:10.1016/j.amjcard.2009.11.021

Cited by 99 publications

(42 citation statements)

References 17 publications

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“…Our study also strengthens the theory that the timing to circulatory support is a key determinant of clinical outcome . Among the therapeutic goals of treating AMI complicated by CS are the rapid stabilization of the patient's hemodynamics and the early reperfusion of the infarct‐related artery to restore normal myocardial metabolism, minimize injury, promote recovery and, ultimately, improve outcomes .…”

Section: Discussionsupporting

confidence: 77%

Percutaneous cardiac assist devices compared with surgical hemodynamic support alternatives

Maini

Gregory²,

Scotti

et al. 2014

Cathet Cardio Intervent

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For patients in CS requiring emergent hemodynamic support, pVAD therapy offers a less invasive alternative that can be deployed sooner, resulting in better outcomes, shorter LOS, lower costs and with no incremental cost, and a survival benefit when compared with traditional surgical hemodynamic support alternatives. PVAD therapy (and Impella 2.5 in particular) is emerging as a dominant strategy for this challenging patient population.

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Section: Discussionsupporting

confidence: 77%

Percutaneous cardiac assist devices compared with surgical hemodynamic support alternatives

Maini

Gregory²,

Scotti

et al. 2014

Cathet Cardio Intervent

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“…The comprehensive search yielded 1093 potentially relevant articles; after exclusion of duplicates and assessment of titles and/or abstracts, 29 articles were chosen for complete review. Finally, nine studies including 1348 patients met our inclusion criteria, published between 2005 and 2017 (Figure S1).…”

Section: Resultsmentioning

confidence: 99%

“…The study conducted by Yuan et al indicated an additional delay of 14 minutes in STEMI patients who received IABP therapy before primary PCI compared to those who underwent primary PCI alone ( P = .04). The study by Abdel‐Wahab et al found a 35‐minute delay in patients who inserted IABP before primary PCI even without statistical difference . Although the delay is short, it can still cause greater damage to the microcirculation and myocardium.…”

Section: Discussionmentioning

confidence: 99%

“…Previous experimental study with animal models of ischemia‐reperfusion demonstrated that unloading the left ventricle with IABP prior to revascularization might provide an additional infarct size reduction. Thereafter, a small population study with 48 patients reported that patients who underwent primary PCI assisted by IABP had a more favorable in‐hospital survival rate than those who received IABP therapy after primary PCI . Contrariwise, Cheng et al (n = 173) found that IABP insertion before PCI was associated with a larger infarct size, and no difference was found between the two strategies regarding short‐term and long‐term mortality .…”

Section: Discussionmentioning

confidence: 99%

“…The main characteristics of the included studies are presented in Table 1 and quality assessment results are described in Tables S2 and S3. Seven studies were observational studies, [21][22][23][24][25][26][27] and the remaining two were sub-analysis of randomized controlled trials. 20,28 Five of the eligible studies only enrolled patients who presented with STEMI, [22][23][24][25]27 and the remaining four included patients with non-STEMI.…”

Section: Eligible Studiesmentioning

confidence: 99%

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Timing of initiation of intra‐aortic balloon pump in patients with acute myocardial infarction complicated by cardiogenic shock: A meta‐analysis

Cui

Lyu

Hong

et al. 2019

Clinical Cardiology

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Background For patients with acute myocardial infarction (AMI) complicated by cardiogenic shock (CS) undergoing primary percutaneous coronary intervention (PCI), the optimal timing of the initiation of intra‐aortic balloon pump (IABP) therapy remains unclear. Therefore, we performed the first meta‐analysis to compare the outcomes of IABP insertion before vs after primary PCI in this population. Methods Electronic databases of PubMed, EMBASE, and Cochrane Library were comprehensively searched from inception to April 1, 2019, to identify the eligible studies. The main outcomes were short‐term (in‐hospital or 30 days) and long‐term (≥ 6 months) mortality. In addition, pooled analysis of risk‐adjusted data were also performed to control for confounding factors. Results Seven observational studies and two sub‐analysis of randomized controlled trials involving 1348 patients were included. Compared to patients inserted IABP after PCI, patients who received IABP therapy before primary PCI had similar risks of short‐term (odds ratio [OR] 0.88, 95% CI 0.49 to 1.59) and long‐term (OR 0.99, 95% CI 0.58 to 1.68) all‐cause mortality. Moreover, a pooled analysis of risk‐adjusted data also found similar effects of the two therapies on short‐term (OR 0.65, 95% CI 0.34 to 1.25) and long‐term (OR 0.68, 95% CI 0.17 to 2.72) mortality. Besides, no significant difference was found between the two groups with respect to reinfarction, repeat revascularization, stroke, renal failure, and major bleeding. Conclusions The timing of the initiation of IABP therapy does not appear to impact short‐term and long‐term survival in patients with AMI complicated by CS undergoing primary PCI.

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Intra-aortic balloon pump counterpulsation (IABP) for myocardial infarction complicated by cardiogenic shock

Unverzagt¹,

Machemer²,

Solms³

et al. 2011

Cochrane Database of Systematic Reviews

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Comparison of Hospital Mortality With Intra-Aortic Balloon Counterpulsation Insertion Before Versus After Primary Percutaneous Coronary Intervention for Cardiogenic Shock Complicating Acute Myocardial Infarction

Cited by 99 publications

References 17 publications

Percutaneous cardiac assist devices compared with surgical hemodynamic support alternatives

Percutaneous cardiac assist devices compared with surgical hemodynamic support alternatives

Timing of initiation of intra‐aortic balloon pump in patients with acute myocardial infarction complicated by cardiogenic shock: A meta‐analysis

Intra-aortic balloon pump counterpulsation (IABP) for myocardial infarction complicated by cardiogenic shock

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