Comparison of Hormonal Treatment Kisspeptin with GnRH and hCG on the some Reproductive Performance of Cyprus, Does during Non-Breeding Season

AL-Ameri, Maad Hasani

doi:10.17582/journal.aavs/2019/7.7.537.542

Cited by 2 publications

(2 citation statements)

References 27 publications

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“…The 1 st parity effect on genes was significantly higher (P<0.05) than 2 nd parity in Cyprus and Iraqi black goats. Our results are in agreement with a previous study in which the litter size of Cyprus goat breeds was recorded as 1.60 [18]. Meanwhile, the results of the present study showed that the litter size of Iraqi black goats in second parity was 1.30±0.020, which is in agreement with a previous study of Juma et al [19], in which a litter size of 1.27±0.14 was recorded in black goats for the treatment with hormones groups in comparison with 1.16±0.16 in a control group in northern Iraq.…”

Section: Discussionsupporting

confidence: 94%

Association of the KiSS1 gene with litter size in Cyprus and Iraqi black goats

Rahawy

Al-Mutar

2021

Vet World

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Aim: The study investigated the genetic polymorphism of the kisspeptin (KiSS1) gene and its relationship with litter size in Cyprus and Iraqi black goats. Materials and Methods: Blood samples (n=124) were collected from the two goat breeds reared at the Agricultural Research-Ruminant Research Station Breeding Station, Baghdad, Iraq. Genomic DNA was isolated using a DNA extraction kit. Polymerase chain reaction (PCR) was used to amplify the KiSS1 gene. All PCR products were sequenced and samples were used for further analysis using NCBI-Blast online on the exon 1 (595 bp) region of the KiSS1 gene. Results: The results of this study revealed a significantly (P<0.05) larger litter size of the Cyprus goat breed than in the Iraqi black goats in the first and second parity. Three (893G/C, 973C/A, and 979T/G) substitutions relative to the KiSS1 gene reference sequence (GenBank ID: J × 047312.1, KC989928.1) were identified. Only the mutation g893G>C was identified as a single nucleotide polymorphism (SNP) associated with litter size. Furthermore, the average alleles in KiSS1 gene of both types of goats 0.567 and 0.3715 GG, were recorded. The genotyping at locus g893C>G was demonstrating domination of fecundity quality litter size, Both genotypes SNP of GC were classified at this marked region of KiSS1 gene. Conclusion: The study concluded that the role of the KiSS1 gene in fecundity, revealing the status of this gene as an indicator in the assisted of caprine breeding selection.

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Section: Discussionsupporting

confidence: 94%

Association of the KiSS1 gene with litter size in Cyprus and Iraqi black goats

Rahawy

Al-Mutar

2021

Vet World

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“…They are cleaved from a single 145 amino acid precursor to peptides ranging from 54 to 10 amino acids in length with equivalent biological activity (10,25,32). Kisspeptins are released from neurons in the hypothalamus and via their receptor (Kiss1r), which is present on GnRH neurons, stimulate GnRH release with a subsequent rise in circulating LH, FSH along with the progesterone in laboratory and livestock animals (5,6,13,30,31). Although GnRH neurons are a critical component of the reproductive axis, Kisspeptin peptides have been identified recently as vital upstream regulators that integrate central and peripheral signals with GnRH release, thereby playing a pivotal role in the control of reproduction (16, 34).…”

Section: Introductionmentioning

confidence: 99%

Effect of Kispeptin-10 as an Alternative to Ecg in Estrus Synchronization Protocol on Improving the Reproductive Performance of Karadi Ewes

Abdulkareem¹,

Muhammad²,

Yousif³

2021

Iraqi J. Agric. Sci.

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This study was conducted to examine the effect of Kisspeptin-10 as an alternative to equine chorionic gonadotropin (eCG) in estrus- synchronization protocol for improving the reproductive performance of Karadi ewes. Forty adult ewes of 3-7 years old and 65–70 kg live body weight were equally divided into four equal groups. Animals were inserted with a progestagen (60 mg MAP)-impregnated sponges for 13 days as estrus synchronization protocol. Following withdrawal of sponges, first group was served as control (C) and intramuscularly injected with normal saline only. The second group was intramuscularly injected with 250 IU of eCG (eCG), while those of third and fourth groups were intravenously injected with 4 and 8 µg /kg body weight of Kisspeptin-10, referred as Kisspeptin1 and Kisspeptin2 groups respectively. Serum progesterone and LH concentrations did not significantly differ among groups before estrus synchronization protocol and eCG or Kisspeptin treatments. The two Kisspeptin-injected groups attained better (P≤0.01) overall mean estrus (100%), fertility (90%), conception (90 and 100%, respectively), lambing (90%), and twinning (10%) rates with lesser barrenness (10%) as compared with the other groups. Moreover, eCG and Kisspeptin groups exhibited greater (P≤ 0.01) percentage of increasing fecundity (233%) and extra lambs born (0.7) than the control group. In conclusion, treatment of Karadi ewes either with Kisspeptin-10 or eCG hormones enhanced the overall reproductive performance, but did not affect serum progesterone and LH concentrations.

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Comparison of Hormonal Treatment Kisspeptin with GnRH and hCG on the some Reproductive Performance of Cyprus, Does during Non-Breeding Season

Cited by 2 publications

References 27 publications

Association of the KiSS1 gene with litter size in Cyprus and Iraqi black goats

Association of the KiSS1 gene with litter size in Cyprus and Iraqi black goats

Effect of Kispeptin-10 as an Alternative to Ecg in Estrus Synchronization Protocol on Improving the Reproductive Performance of Karadi Ewes

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