2003
DOI: 10.1016/s0960-0760(03)00034-7
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Comparison of hormonal activity (estrogen, androgen and progestin) of standardized plant extracts for large scale use in hormone replacement therapy

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Cited by 137 publications
(92 citation statements)
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“…Indeed, Black Cohosh does not bind neither to α nor β receptors [26,27], and it inhibits the proliferation of MCF-7 cells, that are the human breast cancer cell lines more responsive to the estrogenic action [28][29][30].…”
Section: Discussionmentioning
confidence: 99%
“…Indeed, Black Cohosh does not bind neither to α nor β receptors [26,27], and it inhibits the proliferation of MCF-7 cells, that are the human breast cancer cell lines more responsive to the estrogenic action [28][29][30].…”
Section: Discussionmentioning
confidence: 99%
“…Основные изофлавоны клевера (биоханин А, формононетин, даидзеин, генистеин) и ку-местрол оказывают селективное действие на рецепторы эстрогена, связываясь преи-мущественно с β-эстрогеновыми рецепто-рами. Доказано, что изофлавоноиды оказы-вают благотворное воздействие на костную ткань, сердечно-сосудистую систему, голов-ной мозг, слизистую влагалища, не влияя при этом на эндометрий и морфо-функцио-нальное состоя ние молочных желез [6,8]. Стандартизированный по изофлавоноидам экстракт клевера применяют для уменьше-ния вазомоторных симптомов в перименопа-узе, профилактики атеросклероза и развития остеопоротических процессов в организме.…”
Section: климактерический синдром как первое клиническое проявление пunclassified
“…However, the majority of the literature on hormonal effects of herbs focuses on the estrogen activity of herbs commonly used for treating menopause. In preclinical trials, soy isoflavones and red clover extracts have been shown to have estrogenic activity of uncertain clinical significance for estrogen receptor-positive breast cancer patients [55]. Black cohosh, although mistakenly referred to as a phytoestrogen, does not appear to have estrogenic activity as tested in a variety of in vitro, animal, and human studies [56][57][58].…”
Section: Risks Of Alternative Cancer Carementioning
confidence: 99%