Comparison of Hemodynamic Performance of Self-Expandable CoreValve Versus Balloon-Expandable Edwards SAPIEN Aortic Valves Inserted by Catheter for Aortic Stenosis

Hemodynamic changes after transcatheter aortic valve implantation during sequential follow-ups in patients with bicuspid aortic valve compared with tricuspid aortic valve

“…It is noteworthy that in this study, the self-expanding valve was the only device available at that time. It has been shown in several studies that self-expanding CoreValve prosthesis is associated with a lower residual gradient and greater valve area than balloon-expandable Edwards SAPIEN prosthesis [20]. This superior antegrade hemodynamic performance could be explained by it being at supra-annular position, thus, it may exert a lower resistance towards left ventricular outflow [20].…”

Propensity score matched comparison of transcatheter aortic valve implantation versus conventional surgery in intermediate and low risk aortic stenosis patients: A hint of real-world

“…The high-rate of self-expandable prosthesis may partially explain both facts. The supravalvular position of the leaflets in this device has been related to better transvalvular gradients when compared to conventional surgery and to balloon-expandable prosthesis [37,38]. What is more, the use of this prosthesis has been associated to higher rate of paravalvular leak, which indeed was related to higher mortality [39,40].…”

Transcatheter aortic valve replacement

“…6,7,38 As yet, there are no randomized controlled trials comparing the outcome of TAVR using the SAPIEN valve and CoreValve, but, at the time of writing, data from registries and retrospective matched comparisons do not indicate that valve design has a significant impact on survival and most major postoperative complications. 9,10,63 There is clear evidence that the risk of heart block that requires a permanent pacemaker is higher after CoreValve implantation, which might be due to the extended frame expanding into the left-ventricular outflow tract. 1,10,[63][64][65][66] Several studies have further suggested that paravalvular and central regurgitation might be more common after CoreValve implantation, 9,10,63 while others have been unable to demonstrate significant differences.…”

“…9,10,63 There is clear evidence that the risk of heart block that requires a permanent pacemaker is higher after CoreValve implantation, which might be due to the extended frame expanding into the left-ventricular outflow tract. 1,10,[63][64][65][66] Several studies have further suggested that paravalvular and central regurgitation might be more common after CoreValve implantation, 9,10,63 while others have been unable to demonstrate significant differences. 64 Some studies support that the SAPIEN valve might be associated with higher gradients and lower orifice areas, and that this valve might carry a higher risk of coronary artery obstruction.…”

“…64 Some studies support that the SAPIEN valve might be associated with higher gradients and lower orifice areas, and that this valve might carry a higher risk of coronary artery obstruction. 6,63 However, as randomized controlled trials comparing devices for TAVR are pending, no evidence-based recommendation for one of the devices can be given.…”