Comparison of Halothane/Thiopental and Propofol Anesthesia for Strabismus Surgery

Abstract

Day case surgery has become a widely accepted practice for many ophthalmological procedures including strabismus surgery. Prompt recovery from anesthesia and minimal postoperative morbidity are especially requested to the anesthesiologists to deal with the high day case surgery burden. The purpose of this study was to compare two anesthesia techniques, halothane/thiopental anesthesia and propofol anesthesia, for patients undergoing monocular strabismus surgery. We studied the level of postoperative consciousness, nausea and vomiting, ocular pain, starting oral intake and activity in 43 patients, ranging from 7 to 41 years of age. A scoring system was used to assess these parameters in the first postoperative 48 h. Although there was not a significant difference in the level of ocular pain, the propofol group had less morbidity in terms of having a better level of consciousness and appetite, less nausea and vomiting and enhanced activity than the halothane/thiopental group. We conclude that propofol anesthesia has significant advantages over halothane/thiopental anesthesia on an outpatient basis for strabismus surgery.

Postoperative hunger after outpatient surgery in patients anesthetized with propofol vs sevoflurane: a randomized-controlled trial

“…9 In clinical studies, compared with isoflurane or halothane, propofol has been reported to enhance a return of the patient's appetite after neurosurgery 10 and ophthalmological procedures. 11 While it has been claimed that propofol is associated with an intense feeling of hunger in outpatients undergoing colonoscopy, no corroborating data were provided. 12 To further our understanding of the influence of anesthetics on postoperative appetite, we compared the effects of propofol with sevoflurane on appetite and plasma levels of peptides involved in food intake.…”

Combined propofol sedation with sub-Tenon's lidocaine/mercaine infusion for strabismus surgery in adults

“…Similar findings were reported by others for propofol alone or combined with N 2 O or fentanyl and midazolam, thiopentone/halothane, and thiolenthal/halothane. [1][2][3][4]32,33 Although some authors found that propofol (owing to its parasympathetic effects) was associated with more OCR and atrioventricular rhythm disorders than other agents, such as sevoflurane, 3,34 halothane, or ketamine/ midazolam, 3 and a greater need for atropine treatment, 3 in our series, OCR occurred less often in the study than the control group (19 vs 50%), as did bradycardia regarding treatment (0 vs 25%). Hence, the operative time was shorter in the study group because of fewer interruptions.…”

“…Supplemental local anaesthesia was given as necessary. [1][2][3][4][5][6][7][8][9][10] 9.3 (8-10) 7.6 (6-9) 0.003 Surgeon satisfaction (scale 1-10) a 9.0 (6-10) 8.0 (6-9) 0.007 EOM, extraocular muscle; PONV, postoperative nausea/vomiting; SD, standard deviation; VAS, Visual Analog Scale. a In the study group, 13 patients (81.3%) had a score of 9-10 and three, with partial airway obstruction and head movement, had a score of 6-8; in the control group, only six patients (37.5%) had a score of 9.…”

“…Today, surgery may be performed with less morbidity compared to the past using general, [1][2][3][4] retrobulbar, [5][6][7][8][9][10][11] or peribulbar anaesthesia, [11][12][13][14] sub-Tenon's anaesthesia, [15][16][17][18][19][20] or combinations of sedation/topical, 21,22 sedation/peribulbar, 23 and sedation/local techniques. 24 General anaesthesia, [1][2][3][4] however, involves more risk of serious cardiac, respiratory, and central nervous system complications. Retrobulbar [6][7][8][9]11,19 and peribulbar 11,13,14,25 anaesthesia may be associated with these same risks from inadvertent injection of the agents into the venous system or central nervous system, as well as with ocular complications, such as globe perforation, retrobulbar haemorrhage, retinal vascular occlusion, optic nerve injury, contralateral amaurosis, and general disorientation.…”

Anesthetic drugs modulate feeding behavior and hypothalamic expression of the POMC polypeptide precursor and the NPY neuropeptide

“…Propofol also exerts anesthesia through stimulation of the GABA A R [ 16 ]. Furthermore, it has also been shown to stimulate appetite and feelings of hunger in the post-operative recovery period in humans [ 7 , 8 , 11 , 23 ]. Our results are in agreement with this observation because propofol administration markedly favored appetite in mice.…”