Comparison of Halothane and Isoflurane for Rapid Anesthetic Induction

Loper, Keith A.; Reitan, John A.; Bennett, Henry L.; Benthuysen, James L.; Snook, Lee

doi:10.1213/00000539-198708000-00013

Cited by 25 publications

(12 citation statements)

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“…The single-breath technique has repeatedly been shown to reduce the incidence of complications during induction [5][6][7][8]. Other efforts advocated to minimize these airway complications include premedication with opioids [2] and benzodiazepines [9] as well as the use of humidified inspired gases [10]. Premedication may, however, modify the breathholding time and delay the resumption of regular breathing as a result of the respiratory-depressant effects of these drugs.…”

Section: Discussionmentioning

confidence: 99%

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Inhalational induction with isoflurane: the influence of lidocaine pretreatment

Cheong

Khoo

1996

J Anesth

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The effect of intravenous lidocaine in reducing the incidence of complicated induction during a single vital capacity breath technique using isoflurane was studied. Forty patients were randomized into two groups to receive either placebo (group A) or intravenous lidocaine 1.5 mg·kg (group B) just prior to induction. Inhalational induction using 2% isoflurane and 66% nitrous oxide in oxygen was then carried out. Patients pretreated with lidocaine had significantly fewer complications during induction of anesthesia. Modest decreases in blood pressure and heart rate were observed in both groups but were clinically insignificant. Intravenous lidocaine pretreatment significantly reduced the incidence of complications during inhalational induction.

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Section: Discussionmentioning

confidence: 99%

“…Inhalational induction of anesthesia with a single vital capacity breath technique using halothane or isoflurane has been previously described [1,2]. Isoflurane should result in faster induction of anesthesia than halothane because of its lower blood-gas partition coefficient.…”

Section: Introductionmentioning

confidence: 99%

Inhalational induction with isoflurane: the influence of lidocaine pretreatment

Cheong

Khoo

1996

J Anesth

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“…This was very surprising, however, because in our experience conventional inhalation induction with isoflurane has more complications such as coughing or breath holding, and inhalation of high concentrations causes more complications than the conventional method. Loper et al [5] used fentanyl in the singlebreath induction with isoflurane to overcome the complications caused by the pungent odor and irritability to the airways [6].…”

Section: Discussionmentioning

confidence: 99%

Rapid induction with 7% sevoflurane inhalation—not the single-breath method

et al. 1995

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The usefulness of the rapid anesthesia induction method with 7% sevoflurane, not the single-breath method, was investigated in 88 patients with ASA physical status 1. Anesthesia was induced with 3 l·min(-1) nitrous oxide in 3 l·min(-1) oxygen and sevoflurane 7% for 3 min (group A), 7% for 5 min (group B), 7% for 7 min (group C), and 5% for 7 min in conventional induction (group D). There were 22 patients in each group. Each sevoflurane concentration was given at the same time as the start of nitrous oxide inhalation except for group D. The changes in blood pressure and heart rate were the smallest in group A. The time for the loss of consciousness was shorter in groups A (47.2 s), B (44.9 s), and C (49.8 s) than in group D (73.4 s). During induction, body movements were seen in 18.2% in group A and 13.6% in the other 3 groups, but no other complications such as coughing, breath holding, or laryngospasm were seen in any group. In conclusion, the anesthesia induction method with 3 min of 7% sevoflurane inhalation was useful for rapid induction.

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“…Since 1985, several other investigators have reported the merits and safety of this technique with other inhaled anesthetics. In 1987, the VCRII technique was applied using isoflurane [3]. A direct relationship was observed between the blood/gas partition coefficient and the speed of induction.…”

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confidence: 99%

The history of the debate on whether an intravenous or an inhaled anesthetic is the better method for induction

Inomata

2002

Journal of Anesthesia

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Comparison of Halothane and Isoflurane for Rapid Anesthetic Induction

Cited by 25 publications

References 0 publications

Inhalational induction with isoflurane: the influence of lidocaine pretreatment

Inhalational induction with isoflurane: the influence of lidocaine pretreatment

Rapid induction with 7% sevoflurane inhalation—not the single-breath method

The history of the debate on whether an intravenous or an inhaled anesthetic is the better method for induction

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