Comparison of haemodynamics in carotid endarterectomy: primary closure versus patch angioplasty

Jung, Hyun-Woo; Kang, Taehak; Lee, Chul-Hyung; Woo, Shin‐Young; Yang, Shin‐Seok; Mukherjee, Debanjan; Kim, Dong Ik; Ryu, Jaiyoung

doi:10.1080/19942060.2022.2102078

Cited by 5 publications

(5 citation statements)

References 57 publications

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“…Employing ParaView, the calculations results post-processing were conducted for all 89 designed models to obtain the distributions of hemodynamic indices OSI (Oscillatory Shear Index), TAWSS (Time-Averaged Wall Shear Stress), RRT (Relative Residence Time) [2,14,15] on their walls. Given its reliance on both the shear stress and the oscillation of near-wall flow, an RRT-index was taken as a prime indicator of atherogenesis risks.…”

Section: Post-processing and Hemodynamic Indices Calculationmentioning

confidence: 99%

“…Given its reliance on both the shear stress and the oscillation of near-wall flow, an RRT-index was taken as a prime indicator of atherogenesis risks. On the wall of each model, zones were built in which the RRT exceeds the critical value of 6.25 Pa -1 , [15,16] referred to as "critical zones". Thereafter, assessments of integral RRT values (referred to as RRT_int) were provided across the most important in the medical sense parts of these zones.…”

Section: Post-processing and Hemodynamic Indices Calculationmentioning

confidence: 99%

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The influence of inlet flow asymmetry on the carotid bifurcation hemodynamics

Borisov,

Zakharov,

Derbilova

et al. 2024

J. Phys.: Conf. Ser.

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Arterial bifurcations are known to be high-risk areas for the initiation of atherosclerosis. The appearance and growth of atherosclerotic plaques in the bifurcation of the carotid artery can result in severe consequences such as cerebrovascular accidents. The common signs of an atherogenic risk center around the surpassing critical values by certain hemodynamic indices, which are distributed over the artery wall. These indices are related to the effect of blood flow on the arterial wall, and their distribution is influenced by both the bifurcation’s geometric shape and the flow structure at its inlet. The objective of this study is to carry out a comparative analysis of hemodynamic indices in personal-specific models of carotid bifurcation with centrally symmetric and asymmetric input flows. The examined geometric models of bifurcation are based on computed angiography data obtained from the individuals free of apparent pathology. By using computational fluid dynamics within these models, the distribution of hemodynamic indices in a steady periodic flow is calculated and critical zones are determined for them. All the models are divided into two groups – those with symmetric and those with asymmetric input flows. For each model with asymmetric input flow, an alternative geometry is designed to ensure inlet flow symmetry, and comparative numerical calculations of the blood flow are carried out. The results of comparative analysis reveal that the distribution of hemodynamic indices is simpler for the group with symmetric input flow. A comparison of the averages between these two groups with symmetrical and natural asymmetric input flows indicates a 55% better result for the latter group. Furthermore, for almost all models with asymmetric input flow, their alternative models give worse hemodynamic results. Thus, hemodynamic indices in simpler models with symmetrical input flow can serve as an upper estimate for indices in models with natural asymmetric flow. A total of 89 models are included in the study.

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Section: Post-processing and Hemodynamic Indices Calculationmentioning

confidence: 99%

Section: Post-processing and Hemodynamic Indices Calculationmentioning

confidence: 99%

The influence of inlet flow asymmetry on the carotid bifurcation hemodynamics

Borisov,

Zakharov,

Derbilova

et al. 2024

J. Phys.: Conf. Ser.

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“…Based on the RRT values, the distribution of critical zones was constructed, 'critical zones' here refers to the areas on the artery inner wall in which RRT index exceeds the value of 6.25 Pa −1 (critical value). The indicated critical value is calculated from the critical TAWSS and OSI values, given in literature (Harrison et al 2014, Domanin et al 2019, Jung et al 2022. Outside these zones, the risk of atherosclerotic events is minimal.…”

Section: Numerical Calculations and Post-processingmentioning

confidence: 99%

Mathematical modeling in assessing the risk of restenosis after carotid endarterectomy

Borisov,

Zakharov,

Vinogradov

et al. 2024

Biomed. Phys. Eng. Express

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Carotid endarterectomy is the main way to combat atherosclerosis of the carotid arteries, which disrupts cerebral circulation. The generally accepted marker of atherogenesis risk are hemodynamic indices associated with near-wall shear stress. The purpose of the work is to conduct a comparative analysis of hemodynamic indices in various carotid bifurcation models. The influence of a virtual change in the geometric shape of the model in order to optimize hemodynamic indices is also being studied. On the basis of computed angiography data, carotid bifurcation models are constructed, in which critical zones of hemodynamic indices are built using computational fluid dynamics. A comparative analysis of the critical zones for different classes of models is carried out. Comparison of averaged indices for critical zones between 'normal' and post-operative groups gave more than 5-x worse results for the latter. The same results for the near-bifurcation parts of the zones give a 25% better result for postoperative models. Virtual ‘removal’ of insignificant plaques leads to a deterioration of the indices of up to 40% in the places of the plaque’s former location. The described method makes it possible to build the indices critical zones and compare them for various types of models. A technique for virtual changing the shape of a vessel (virtual surgery) is proposed. The novelty of the approach lies in the use for comparative analysis both real vessel models and hypothetical ‘improved’ virtual ones, as well in the proposed division of post-operative model’s critical zones into subzones of different genesis.

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“…A primary etiological factor of stroke is carotid artery stenosis, which is predominantly caused by the build-up of atherosclerotic plaque [1]. Furthermore, the formation and development of atherosclerotic plaques are highly influenced by the hemodynamic environment in the carotid artery [2]. However, the impact of an elevated heart rate on the hemodynamic milieu in carotid arteries of differing stenosis degrees, utilizing healthy carotid arteries as reference controls, has been seldom reported in the open literature.…”

Section: Extended Abstractmentioning

confidence: 99%

Carotid Artery Digital Twin Based On Reduced-Order Model

Chen,

Cheng,

Luo

et al. 2024

Proceedings of the 9th World Congress on Momentum, Heat and Mass Transfer

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Comparison of haemodynamics in carotid endarterectomy: primary closure versus patch angioplasty

Cited by 5 publications

References 57 publications

The influence of inlet flow asymmetry on the carotid bifurcation hemodynamics

The influence of inlet flow asymmetry on the carotid bifurcation hemodynamics

Mathematical modeling in assessing the risk of restenosis after carotid endarterectomy

Carotid Artery Digital Twin Based On Reduced-Order Model

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