Comparison of Golytely lavage with standard diet/cathartic preparation for double-contrast barium enema

Girard, Chloé; Rugh, K. S.; DiPalma, Jack A.; Brady, Charles E.; Pierson, Wayne P.

doi:10.2214/ajr.142.6.1147

Cited by 25 publications

(5 citation statements)

References 19 publications

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“…Protocols not using magnesium can achieve a good cleansing, but there is usually failure to get good barium mucosal coating. This, for example, is what happens with conventional PEG-ELS [14,15].…”

Section: Discussionmentioning

confidence: 93%

Do magnesium ions influence barium mucosal coating of the large bowel?

et al. 1999

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The aim of the present study was to verify whether the presence of magnesium in the colon lumen at the time of the double-contrast barium enema (DCBE) examination changes the quality of barium mucosal coating. The two members of 38 pairs of patients undergoing DCBE with a standardised technique were randomly subjected to bowel preparation with sennosides and magnesium sulphate, or sennosides and sodium sulphate. Mucosal coating, residual fluid and colon cleansing were assessed independently by three radiologists. The null hypothesis was tested by means of Wilcoxon's signed-rank test. Barium mucosal coating was judged to be better in the members to whom magnesium sulphate was administered (p = 0.0007). There was no difference in the amount of residual fluids (p = 0.3198). Colon cleansing was judged to be better in the members to whom sodium sulphate was administered (p = 0.0166). These results demonstrate, in a simple way, that magnesium ions increase barium coating of the colon mucosa in vivo. The underlying mechanisms (increase in viscosity of barium suspension through water subtraction owing to the hydrophilism of magnesium ions, or interactions with the polysaccharide additives) need further investigation. A first clinical application could be the integration of magnesium ions in a newly designed isotonic electrolyte solution containing polyethylene glycol for the oral colon wash-out.

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Section: Discussionmentioning

confidence: 93%

Do magnesium ions influence barium mucosal coating of the large bowel?

et al. 1999

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“…There is often excess fluid in the colon after oral polyethylene glycol 3350 lavage. 20,21 Excess fluid in the colon adversely affects imaging examinations of the colon except dark-lumen MRC 4 and the MMC technique. On the contrary, excess fluid decreases the density of the barium suspension in the right colon and tends to lessen the effort required in examining the caecum and ascending colon.…”

Section: Discussionmentioning

confidence: 99%

The Modified Mayo Clinic technique: Emphasis on plausible significant reduction of colon cancer

Lui¹

2014

J Int Med Res

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“…In this way, data about tolerance and costs of a specific method are of importance and should be taken into account when indicating one of them. [13][14][15][16] The present study provides an actual evaluation of costs associated with three methods, taking into account the commercial value of the products. A small difference was observed between the MN and NaP solutions, being the last one more affordable.…”

Section: Discussionmentioning

confidence: 99%

Comparison of colon-cleansing methods in preparation for colonoscopy - Comparative efficacy of solutions of mannitol, sodium picosulfate and monobasic and dibasic sodium phosphates

et al. 2008

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PURPOSE: Colonoscopy plays an essential role in the therapeutic and diagnostic approach in various colonic pathologies, the aim of the present study was to compare three solutions and their efficacy for the bowel preparation in adult patients submitted to elective colonoscopy. METHODS: Sixty patients were randomly divided into three groups of 20 each. Each group was submitted to a bowel preparation with one of the following solutions: 10% manitol, sodium picosulphate or sodium phosphate. The parameters evaluated were: taste, tolerance, associated side effects and quality of cleansing. Postural blood pressure and pulse rate as well as serum sodium, potassium, calcium and phosphate were compared. RESULTS: Sodium phosphate and 10% manitol solutions provided superior results in terms of colon cleansing compared to sodium picosulphate solution. All serum electrolytes evaluated were significantly altered in the three groups, without important clinical signs. DISCUSSION: High levels of serum phosphate were the most striking alteration in patients prepared with sodium phosphate solution, again with no clinical signs. Variations related to blood pressure and pulse rate suggested contraction of intravascular volume, with no clinical effects. CONCLUSION: Sodium phosphate and 10% manitol solutions are equivalent in providing good quality colon cleansing, with no significant side effects that could compromise the procedure.

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Comparison of Golytely lavage with standard diet/cathartic preparation for double-contrast barium enema

Cited by 25 publications

References 19 publications

Do magnesium ions influence barium mucosal coating of the large bowel?

Do magnesium ions influence barium mucosal coating of the large bowel?

The Modified Mayo Clinic technique: Emphasis on plausible significant reduction of colon cancer

Comparison of colon-cleansing methods in preparation for colonoscopy - Comparative efficacy of solutions of mannitol, sodium picosulfate and monobasic and dibasic sodium phosphates

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