Comparison of Goldmann applanation tonometry with the Tonopen for measuring intraocular pressure in a population-based glaucoma survey in rural West Bengal

Bandyopadhyay, Mausumi; Raychaudhuri, Amitabha; Lahiri, Saibendu Kumar; Schwartz, Ellen; Myatt, Mark; Johnson, Gordon J.

doi:10.1076/opep.9.3.215.1518

Cited by 34 publications

(31 citation statements)

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“…However, we found substantial agreement between the 2 modes of IOP measurement, as has been reported elsewhere. 38 This argues against systematic error due to instrumentation.…”

Section: Discussionmentioning

confidence: 99%

“…However, we found substantial agreement between the 2 modes of IOP measurement, as has been reported elsewhere. 38 This argues against systematic error due to instrumentation.We estimated the heritability of CDR to be 0.56, which compares well with the previous reported values of 0.48 to 0.80. 24,26 It is not surprising that a simple cross-sectional measurement of CDR should show higher heritability than IOP, which exhibits substantial diurnal variation and is more sensitive to the effects of environmental influences such as drugs.…”

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confidence: 99%

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Determinants and Heritability of Intraocular Pressure and Cup-to-Disc Ratio in a Defined Older Population

et al. 2005

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Purpose-To investigate the heritability of intraocular pressure (IOP) and cup-to-disc ratio (CDR) in an older well-defined population. Design-Family-based cohort study.Participants-Through the population-based Salisbury Eye Evaluation study, we recruited 726 siblings (mean age, 74.7 years) in 284 sibships.Methods-Intraocular pressure and CDR were measured bilaterally for all participants. The presence or absence of glaucoma was determined by a glacuoma specialist for all probands on the basis of visual field, optic nerve appearance, and history. The heritability of IOP was calculated as twice the residual between-sibling correlation of IOP using linear regression and generalized estimating equations after adjusting for age, gender, mean arterial pressure, race, self-reported diabetes status, and history of systemic steroid use. The heritability of CDR was calculated using the same model and adjustments as above, while also adjusting for IOP.Main Outcome Measures-Heritability and determinants of IOP and CDR, and impact of siblings' glaucoma status on IOP and CDR.Results-We estimated the heritability to be 0.29 (95% confidence interval [CI], 0.12-0.46) for IOP and 0.56 (95% CI, for CDR in this population. Mean IOP in siblings of glaucomatous probands was statistically significantly higher than in siblings of normal probands (mean difference, 1.02 mmHg; P = 0.017). The mean CDR in siblings of glaucomatous probands was 0.07 (or 19%) larger than in siblings of glaucoma suspect referrals (P = 0.045) and siblings of normal probands (P = 0.004).Conclusions-In this elderly population, we found CDR to be highly heritable and IOP to be moderately heritable. On average, siblings of glaucoma patients had higher IOPs and larger CDRs than siblings of nonglaucomatous probands.Primary open-angle glaucoma (POAG) is the second most common cause of blindness in the world 1 and affects approximately 2.2 million Americans. 2 Although the diagnosis of POAG centers on the characteristic excavation and atrophy of the optic nerve head and functional deficit measured by visual field (VF) change, 3 the heritability of intraocular pressure (IOP) and cup-to-disc ratio (CDR) have not been studied extensively thus far, despite the wellestablished role of heredity in POAG. In this study, we estimate the heritability of IOP and CDR from a cohort of sibships recruited through the Salisbury Eye Evaluation study. In addition, we also report the distribution of IOP and CDR among siblings of glaucomatous probands versus siblings of normal probands. Materials and Methods Subjects and General DesignBetween 1993 and 1995, a random sample of potential participants (ages 65 to 84 years) was chosen from the Health Care Financing Administration Medicare database and recruited from Salisbury, located on the Eastern Shore of Maryland, to engage in the population-based Salisbury Eye Evaluation study. 28 The cohort was invited for a follow-up examination including VF testing, optic nerve head imaging, and IOP measurement. All subjects with abnormal scr...

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“…However, we found substantial agreement between the 2 modes of IOP measurement, as has been reported elsewhere. 38 This argues against systematic error due to instrumentation.…”

Section: Discussionmentioning

confidence: 99%

mentioning

confidence: 99%

Determinants and Heritability of Intraocular Pressure and Cup-to-Disc Ratio in a Defined Older Population

et al. 2005

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“…The hospital setting had more patients with high IOP ranges and measurement of IOP with a Tonopen is known to be less accurate at extreme values. 30,31 There was moderate level of agreement (k ¼ 0.52, s.e. ¼ 0.0359) on VCDR assessment in the community setting.…”

Section: Discussionmentioning

confidence: 99%

Evaluation of the effectiveness of ophthalmic assistants as screeners for glaucoma in North India

Sinha¹,

Astbury

2011

Eye

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Aim To assess whether ophthalmic assistants are effective in screening people for glaucoma in India. Methodology The study subjects were examined by both trained ophthalmic assistants and an ophthalmologist in both hospital and community settings. Specific tests for the diagnosis of glaucoma suspects included visual field examination using frequency doubling technology perimetry, intraocular pressure measurement (Tonopen), A-scan central anterior chamber depth measurement and dilated optic disc examination. The findings recorded by the ophthalmic assistants were masked to the ophthalmologist to avoid measurement bias. Results In the hospital setting, there was a substantial level of agreement between the ophthalmic assistants and the ophthalmologist in the diagnosis of glaucoma suspects (89.29%, k ¼ 0.7, 95% confidence interval (CI) ¼ 0.54-0.86). The diagnostic accuracy of the ophthalmic assistants in detecting glaucoma suspects was high for sensitivity (95.2%, 95% CI ¼ 91.4-97.7%) but lower for specificity at 71.4% (95% CI ¼ 60.0-78.7%). In the community setting, there was a moderate level of agreement between the ophthalmic assistants and the ophthalmologist in the diagnosis of glaucoma suspects (78.23%, k ¼ 0.50, 95% CI ¼ 0.37-0.64). The diagnostic accuracy of the ophthalmic assistants in detecting glaucoma suspects was moderate for sensitivity (82.9, 95% CI ¼ 69.7-91.5%) but lower for specificity at 76.8% (95% CI ¼ 72.7-79.5%). Conclusion Ophthalmic assistants can be used for opportunistic case detection of glaucoma suspects in the community. Structured training of the ophthalmic assistants together with enhanced clinical experience would improve their performance in detecting glaucoma suspects in the community.

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“…In eight studies 75,107,140,144,153,157,166,169 (53%), the tonometers used were calibrated. Almost all studies 107,138,140,144,153,157,166,188,191,197,206,207,216 (13, 87%) included all participants approached in the analysis or stated a reason why not. The Salvetat 144 study met all of the specified criteria.…”

Section: Quality Assessmentmentioning

confidence: 99%

“…In total, 642 reports were identified from the electronic searches as being possibly relevant. [189][190][191][192] three in each of Saudi Arabia, [193][194][195] India, [196][197][198] Portugal 106,199,200 and Greece [201][202][203] and two in Taiwan, 125,204 Israel, 205,206 the Netherlands, 207,208 Sweden 209,210 and Turkey. 211,212 One study took place in each of Austria, 126 Brazil, 213 France, 123 Ireland, 214 New Zealand, 215 Norway 216 and Denmark.…”

Section: Overviewmentioning

confidence: 99%

Surveillance for ocular hypertension: an evidence synthesis and economic evaluation

2012

Clinical Governance: An International Journal

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How to obtain copies of this and other HTA programme reports An electronic version of this title, in Adobe Acrobat format, is available for downloading free of charge for personal use from the HTA website (www.hta.ac.uk). A fully searchable DVD is also available (see below).Printed copies of HTA journal series issues cost £20 each (post and packing free in the UK) to both public and private sector purchasers from our despatch agents.Non-UK purchasers will have to pay a small fee for post and packing. For European countries the cost is £2 per issue and for the rest of the world £3 per issue. How to order:-fax (with credit card details) -post (with credit card details or cheque) -phone during office hours (credit card only).Additionally the HTA website allows you to either print out your order or download a blank order form. Contact details are as follows:Synergie UK (HTA Department) Digital House, The Loddon Centre Wade Road Basingstoke Hants RG24 8QW Email: orders@hta.ac.uk Tel: 0845 812 4000 -ask for 'HTA Payment Services' (out-of-hours answer-phone service) Fax: 0845 812 4001 -put 'HTA Order' on the fax header Payment methods Paying by chequeIf you pay by cheque, the cheque must be in pounds sterling, made payable to University of Southampton and drawn on a bank with a UK address.Paying by credit card You can order using your credit card by phone, fax or post. SubscriptionsNHS libraries can subscribe free of charge. Public libraries can subscribe at a reduced cost of £100 for each volume (normally comprising 40-50 titles). The commercial subscription rate is £400 per volume (addresses within the UK) and £600 per volume (addresses outside the UK). Please see our website for details. Subscriptions can be purchased only for the current or forthcoming volume.How do I get a copy of HTA on DVD?Please use the form on the HTA website (www.hta.ac.uk/htacd/index.shtml). HTA on DVD is currently free of charge worldwide.The website also provides information about the HTA programme and lists the membership of the various committees. HTA NIHR Health Technology Assessment programmeThe Health Technology Assessment (HTA) programme, part of the National Institute for Health Research (NIHR), was set up in 1993. It produces high-quality research information on the effectiveness, costs and broader impact of health technologies for those who use, manage and provide care in the NHS. 'Health technologies' are broadly defined as all interventions used to promote health, prevent and treat disease, and improve rehabilitation and long-term care. The research findings from the HTA programme directly influence decision-making bodies such as the National Institute for Health and Clinical Excellence (NICE) and the National Screening Committee (NSC). HTA findings also help to improve the quality of clinical practice in the NHS indirectly in that they form a key component of the 'National Knowledge Service' . The HTA programme is needs led in that it fills gaps in the evidence needed by the NHS. There are three routes to the start of projects...

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Comparison of Goldmann applanation tonometry with the Tonopen for measuring intraocular pressure in a population-based glaucoma survey in rural West Bengal

Abstract: The overall agreement between the measurements of the two instruments was good but a small percentage of large difference (> or = +/-5 mm Hg in 7.4%) may be of concern in a population-based survey. The time to measure IOP and the subjects' preference were strongly in favour of the Tonopen.

Cited by 34 publications

References 11 publications

Determinants and Heritability of Intraocular Pressure and Cup-to-Disc Ratio in a Defined Older Population

Determinants and Heritability of Intraocular Pressure and Cup-to-Disc Ratio in a Defined Older Population

Evaluation of the effectiveness of ophthalmic assistants as screeners for glaucoma in North India

Surveillance for ocular hypertension: an evidence synthesis and economic evaluation

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