Comparison of Global Decolonization Efficacy with Mupirocin Nasal Drop and Chlorhexidine Mouthwash in Acute Leukemia Patients: Randomized Clinical Trial
Abstract:Purpose
Neutropenic fever remains a major complication in acute leukemia. Decolonization is assumed as a promising intervention for eradicating causative agents of infection
Methods
In this randomized clinical trial, 96 patients with acute leukemia were assigned randomly to mupirocin nasal drop 2% (n = 32), chlorhexidine mouthwash 0.2% (n = 33), and control group (n = 31). In control group patients did not receive any medication for decolonization. All patients received treatment for 5 days (2 days prior to ch… Show more
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