Comparison of Fick and thermodilution cardiac output determinations in standing horses

Lepiz, Mauricio; Keegan, Robert D.; Bayly, W. M.; Greene, Stephen A.; McEwen, Margaret-Mary

doi:10.1016/j.rvsc.2007.10.013

Cited by 6 publications

(3 citation statements)

References 39 publications

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“…Lithium determinations of CO in this study ranged between 16.6 and 63.0 L/min, which represent a wide physiological range of CO and are similar to ranges achieved in comparable studies . Echocardiographic derivation of CO was not influenced by level of CO.…”

Section: Discussionsupporting

confidence: 83%

“…3 Lithium determinations of CO in this study ranged between 16.6 and 63.0 L/min, which represent a wide physiological range of CO and are similar to ranges achieved in comparable studies. 7,44 Echocardiographic derivation of CO was not influenced by level of CO. Although a statistically significant decrease in CO from baseline was not achieved with the romifidine CRI, our purpose of measuring CO over a wide range of values was met.…”

Section: Discussionmentioning

confidence: 92%

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Doppler and Volumetric Echocardiographic Methods for Cardiac Output Measurement in Standing Adult Horses

McConachie

Barton

Rapoport

et al. 2013

Veterinary Internal Medicne

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Background: Cardiac output (CO) is not routinely measured in critically ill adult horses because of invasiveness of currently validated methods. Noninvasive CO monitoring would complement clinical assessment of hemodynamic status in adult horses.Hypothesis: Volumetric methods for measuring CO will have better agreement with lithium dilution than Dopplerbased methods.Animals: Eight healthy adult horses. Methods: Prospective study. CO was manipulated with continuous rate infusions of dobutamine and romifidine to achieve high and low CO states, respectively. At each level, CO was measured by lithium dilution and various echocardiographic methods. Images stored as video loops were reviewed by an individual blinded to the lithium dilution results.Results: Lithium dilution determinations of CO ranged between 16.6 and 63.0 L/min. There was a significant effect of method of CO measurement (P < .001), but no significant effect of CO level (P = .089) or interaction between level and method (P = .607) on the absolute value of the bias. The absolute values of the bias of the right ventricular outflow tract (RVOT) Doppler, Simpson, 4-chamber area-length, and bullet methods [5.5, 6.1, 6.5, 8.8 L/min, respectively] were significantly lower than that of the left ventricular outflow tract (LVOT) Doppler or cubic methods [14.8, 24.3 L/min, respectively].Conclusions and Clinical Importance: The 4-chamber area-length, Simpson, bullet, and RVOT Doppler provided better agreement with lithium dilution than the other methods evaluated. These methods warrant further investigation for use in critically ill adult horses.

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Section: Discussionsupporting

confidence: 83%

Section: Discussionmentioning

confidence: 92%

Doppler and Volumetric Echocardiographic Methods for Cardiac Output Measurement in Standing Adult Horses

McConachie

Barton

Rapoport

et al. 2013

Veterinary Internal Medicne

View full text Add to dashboard Cite

show abstract

“…As in other species, alfaxalone is rapidly cleared from the plasma of the horse. The average plasma clearance in the premedicated horse is approximately 37 mL minute )1 kg )1 , corresponding to approximately 46% of cardiac output in the conscious horse as reported by Loria Lepiz et al (2008). In Beagle dogs, body clearance of alfaxalone was 59.4 mL minute )1 kg )1 (Ferre et al 2006) and in rats 71.9 mL minute )1 kg )1 (Visser et al 2000).…”

Section: Discussionmentioning

confidence: 57%

The pharmacokinetics and pharmacodynamics of the injectable anaesthetic alfaxalone in the horse

Goodwin

Keates

Pasloske

et al. 2011

Veterinary Anaesthesia and Analgesia

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Disorders of the Cardiovascular System

Schwarzwald¹

2018

Equine Internal Medicine

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Comparison of Fick and thermodilution cardiac output determinations in standing horses

Cited by 6 publications

References 39 publications

Doppler and Volumetric Echocardiographic Methods for Cardiac Output Measurement in Standing Adult Horses

Doppler and Volumetric Echocardiographic Methods for Cardiac Output Measurement in Standing Adult Horses

The pharmacokinetics and pharmacodynamics of the injectable anaesthetic alfaxalone in the horse

Disorders of the Cardiovascular System

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