Comparison of Feasibility and Accuracy of Transthoracic Echocardiography Versus Computed Tomography in Patients With Known Ascending Aortic Aneurysm

Tamborini, Gloria; Galli, C.; Maltagliati, Anna; Andreini, Daniele; Pontone, Gianluca; Quaglia, C; Ballerini, G; Pepi, Mauro

doi:10.1016/j.amjcard.2006.04.043

Cited by 57 publications

(38 citation statements)

References 19 publications

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“…97 Mean TTE and MRI measurements of aortic root diameter were the same in another small study, 98 suggesting that TTE is an accurate imaging modality. Nonetheless, 1 study found that interobserver and intraobserver variability of echocardiogram interpretations was 6%.…”

Section: Image Interpretationmentioning

confidence: 70%

Ascending Aortic Dilatation Associated With Bicuspid Aortic Valve

2009

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Section: Image Interpretationmentioning

confidence: 70%

Ascending Aortic Dilatation Associated With Bicuspid Aortic Valve

2009

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“…For the purposes of the review, we included studies that phenotyped participants using the following imaging tests: transthoracic echocardiogram (TTE)/transoesophageal echocardiogram, computed tomography (CT), or magnetic resonance imaging (MRI) of the thoracic aorta, and genetic screening, individually or in combination with the acknowledgement that sensitivities and specificities of CT (100% and 100%, respectively) and MRI (95–100%) are higher when compared with those of transoesophageal echocardiogram and TTE (74–100% and 71–91%, respectively) 11, 12, 13, 14, 15. In some studies, surgery for TAD, postmortem examination, or sudden death were used to assess the aortic phenotype.…”

Section: Methodsmentioning

confidence: 99%

Systematic Review of Studies That Have Evaluated Screening Tests in Relatives of Patients Affected by Nonsyndromic Thoracic Aortic Disease

Mariscalco

Debiec

Elefteriades

et al. 2018

JAHA

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BackgroundNonsyndromic thoracic aortic diseases (NS‐TADs) are often silent entities until they present as life‐threatening emergencies. Despite familial inheritance being common, screening is not the current standard of care in NS‐TADs. We sought to determine the incidence of aortic diseases, the predictive accuracy of available screening tests, and the effectiveness of screening programs in relatives of patients affected by NS‐TADs.Methods and ResultsA systematic literature search on PubMed/MEDLINE, Embase, and the Cochrane Library was conducted from inception to the end of December 2017. The search was supplemented with the Online Mendelian Inheritance in Man database. A total of 53 studies were included, and a total of 2696 NS‐TAD relatives were screened. Screening was genetic in 49% of studies, followed by imaging techniques in 11% and a combination of the 2 in 40%. Newly affected individuals were identified in 33%, 24%, and 15% of first‐, second‐, and third‐degree relatives, respectively. Familial NS‐TADs were primarily attributed to single‐gene mutations, expressed in an autosomal dominant pattern with incomplete penetrance. Specific gene mutations were observed in 25% of the screened families. Disease subtype and genetic mutations stratified patients with respect to age of presentation, aneurysmal location, and aortic diameter before dissection. Relatives of patients with sporadic NS‐TADs were also found to be affected. No studies evaluated the predictive accuracy of imaging or genetic screening tests, or the clinical or cost‐effectiveness of an NS‐TAD screening program.ConclusionsFirst‐ and second‐degree relatives of patients affected by both familial and sporadic NS‐TADs may benefit from personalized screening programs.

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“…CMR is considered the gold standard for the measurement of aortic diameters [7][8][9][10][11][12][13][14][15]. Adequate TTE views of the mid and distal AA and aortic arch, usually the site of maximum dilatation, can be difficult to obtain in patients with BAV [16].…”

Section: Introductionmentioning

confidence: 99%

Measurement of the ascending aorta diameter in patients with severe bicuspid and tricuspid aortic valve stenosis using dual-source computed tomography coronary angiography

Son

Choi

et al. 2011

Int J Cardiovasc Imaging

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We aimed to evaluate the diagnostic performance of dual-source computed tomography coronary angiography (DSCT-CA) in the measurement of the ascending aorta (AA) diameter and compare the AA diameter in patients with severe bicuspid aortic valve (BAV) and tricuspid aortic valve (TAV) stenosis. Eighty-eight consecutive patients (50 men, mean age 60.3 ± 13 year) with severe aortic stenosis (AS) underwent DSCT-CA before aortic valve surgery. Seventy-four of the 88 patients underwent cardiovascular magnetic resonance (CMR). The internal diameter of AA was measured from early-systole with DSCT-CA and CMR by 2 radiologists independently at 4 levels (aortic annulus, sinuses of Valsalva, sinotubular junction, and tubular portion at the right pulmonary artery). The patients were divided in to 2 groups (BAV [n = 53]; TAV [n = 35]) according to operative findings. Patients with BAV were significantly younger than those with TAV (P = 0.0035). Inter-observer agreement of AA diameters at 4 levels with DSCT-CA and CMR was excellent (intraclass correlation coefficient = 0.89-0.97). Also, the DSCT-CA and CMR measurements of the AA diameter strongly correlated (r = 0.871-0.976). Mean diameter of the AA by DSCT-CA was significantly larger in patients with BAV (34.4 ± 8.2 mm) as compared to those with TAV (30.6 ± 5.5 mm). The diameters at the sinuses of Valsalva, sinotubular junction, and tubular portion were significantly larger in BAV than in TAV. Twenty-two of 53 (41.5%) patients with BAV and 2 of 35 (5.7%) patients with TAV had AA dilatation > 45 mm. DSCT-CA allows accurate assessment of the AA diameters in patients with severe AS. Patients with severe BAV stenosis had larger AA diameters and higher prevalence of AA dilatation > 45 mm as compared to those with severe TAV stenosis.

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Comparison of Feasibility and Accuracy of Transthoracic Echocardiography Versus Computed Tomography in Patients With Known Ascending Aortic Aneurysm

Cited by 57 publications

References 19 publications

Ascending Aortic Dilatation Associated With Bicuspid Aortic Valve

Ascending Aortic Dilatation Associated With Bicuspid Aortic Valve

Systematic Review of Studies That Have Evaluated Screening Tests in Relatives of Patients Affected by Nonsyndromic Thoracic Aortic Disease

Measurement of the ascending aorta diameter in patients with severe bicuspid and tricuspid aortic valve stenosis using dual-source computed tomography coronary angiography

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