Comparison of external radiotherapy, laser microsurgery and partial laryngectomy for the treatment of T1N0M0 glottic carcinomas: a retrospective evaluation

Rosier, Jean-François; Grégoire, Vincent; Counoy, Hubert; Octave-Prignot, M; Rombaut, Philippe; Scalliet, Pierre; Vanderlinden, Fabienne; Hamoir, Marc

doi:10.1016/s0167-8140(98)00058-9

Cited by 95 publications

(103 citation statements)

References 43 publications

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“…It has a cure rate comparable to open partial procedures as well as to primary radiotherapy [2][3][4][5]. Its advantages over other treatment options include minimal morbidity, good functional results, avoidance of tracheostomy, short treatment time, and effective local disease control [6,7].…”

Section: Introductionmentioning

confidence: 99%

The Utility of Second Look Microlaryngoscopy after Trans Oral Laser Resection of Laryngeal Cancer

Shenoy

Prashanth

Shivakumar

et al. 2012

Indian J Otolaryngol Head Neck Surg

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In the past few decades more and more number of tumors of the glottis and supraglottis are been treated with single stage transoral laser microsurgery (TOLS). TOLS for the treatment of glottic and supraglottic carcinoma with anterior commissure (A-com) and/paraglottic space involvement is associated with a high rate of recurrence. We prospectively evaluated the outcomes of laser microsurgery and the impact of second look operation in these patients. Twenty-three patients with glottic and supraglottic carcinoma underwent transoral laser micro resection of the lesions. Subsequently five patients underwent second look microlaryngeal evaluation 6-8 months later for non-satisfactory healing, poor voice, and or suspicion of recurrent disease. Patients with A-com involvement and or paraglottic space involvement were followed up longitudinally for the effectiveness and timing of second look microsurgery. After initial transoral laser micro resection, all patients achieved microscopically clear resection margins. At second look microlaryngeal evaluation, local recurrence was found in four of 23 patients. Of these, two patients were salvaged by second look surgery and are disease free, whereas in two others, the larynx had to be subjected to open surgical intervention. One of two had extensive local recurrent tumor and underwent total laryngectomy with neck dissection followed by postoperative radiotherapy. Tracheohyoidopexy was done with successful functional and oncologic outcome for another patient who had local recurrence for the third time. Only the patient who underwent total laryngectomy with neck dissection was subjected to adjuvant post-operative radiotherapy. Finally, larynx was saved in 21 out of 23 patients.

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Section: Introductionmentioning

confidence: 99%

The Utility of Second Look Microlaryngoscopy after Trans Oral Laser Resection of Laryngeal Cancer

Shenoy

Prashanth

Shivakumar

et al. 2012

Indian J Otolaryngol Head Neck Surg

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“…In one retrospective cohort study, post-treatment voice and speech quality were assessed by clinician perceptual analysis 14 , which found that the difference between surgical and radiation therapy patients did not reach statistical significance. In five studies that analyzed patient self-perception, three [15][16][17] found no statistically significant differences between treatment groups, one 18 found that radiation therapy patients scored significantly better, and one 19 reported that surgically treated patients scored better.…”

Section: Key Evidencementioning

confidence: 99%

Role of Endolaryngeal Surgery (with or without Laser) Compared with Radiotherapy in the Management of Early (T1) Glottic Cancer: A Clinical Practice Guideline

et al. 2013

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“…It was rated to be insufficient to make a conversation in a noisy atmosphere, since it cannot be raised satisfactorily. Rosier et al 14 16 evaluated a series of patients treated at the Mayo Clinic for Tis-T1 glottic carcinoma. They found that the overall charges and costs were similar for patients treated with radiotherapy compared with transoral resection and both treatments were less expensive than open partial laryngectomy.…”

Section: Management Of T1 and T2 Glottic Cancermentioning

confidence: 99%

Comparision of Transoral Laser and Open Partial Laryngectomy for T1 and T2 Glottic Cancer: A Review of literature.

Singh

2012

Int J of Biomed & Adv Res

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T1-T2 glottic carcinomas may be treated with conservative surgery or radiotherapy. The goals of treatment are cure and laryngeal voice preservation. The aim of the current study was to review the literature and discuss the optimal management of T1 and T2 glottic carcinoma. Literature review indicated that the local control, laryngeal preservation, and survival rates of patients were similar after transoral laser resection and open partial laryngectomy. Voice quality depended on the extent of resection for patients undergoing surgery; results for patients undergoing laser resection for limited lesions showed better Voice Handicap Index scores, whereas open partial laryngectomy yielded poorer results. The cost of treatment was more for open partial laryngectomy. Patients with well defined lesions suitable for transoral laser excision with a good functional outcome were treated with laser. Open partial laryngectomy was reserved for patients with locally recurrent tumors. This review has been conducted by analyzing the Data which has been displayed in Pubmed literature in the last 25 years on the topics of Transoral Laser and Open partial Laryngectomy in the management of T1 and T2 glottic cancer. The various original articles and review articles were analyzed and compared and a conclusion derived.

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Comparison of external radiotherapy, laser microsurgery and partial laryngectomy for the treatment of T1N0M0 glottic carcinomas: a retrospective evaluation

Cited by 95 publications

References 43 publications

The Utility of Second Look Microlaryngoscopy after Trans Oral Laser Resection of Laryngeal Cancer

The Utility of Second Look Microlaryngoscopy after Trans Oral Laser Resection of Laryngeal Cancer

Role of Endolaryngeal Surgery (with or without Laser) Compared with Radiotherapy in the Management of Early (T1) Glottic Cancer: A Clinical Practice Guideline

Comparision of Transoral Laser and Open Partial Laryngectomy for T1 and T2 Glottic Cancer: A Review of literature.

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