Comparison of Etomidate and Thiopentone Sodium as Anaesthetic Agents for Modified Electroconvulsive Therapy

Donthu, Balaji; Kavya, Kavya; Subramanyam, Vara

doi:10.14260/jemds/2017/113

Cited by 1 publication

(1 citation statement)

References 17 publications

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“…Propofol had pain on injection as the main side effect, Etomidate had myoclonus and Thiopentone had cough as side effects. Studies conducted by Patil AP et al [19] , Donthu B et al [20] , Mir AH et al [13] showed similar results. These studies are in concurrence with our study.…”

Section: Resultsmentioning

confidence: 55%

Comparison between sodium thiopentone, propofol and etomidate as an induction agent for modified electroconvulsive therapy

Atram¹,

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2020

Int. J. Med. Anesthesiology

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Introduction: Electroconvulsive Therapy is a well-established psychiatric treatment in which seizures are electrically induced in anaesthetized patients for therapeutic effects. Material & Methods: This study was carried out after clearance from the ethical committee. 150 cases were in this study, divided into three equal groups (n=50). Group A was received Propofol 1%, group B received Etomidate, group C received Sodium Thiopentone 2.5%. They were compared as regards induction time, seizure duration, hemodynamic effects, recovery from anaesthesia & immediate side effects. Result: Induction was quicker in Propofol group i.e. 44.3 /5.02 s than in Etomidate 52.54 / 5.21 s and 50.16 / 5.68 s. Seizure duration was significantly higher in Etomidate 29.34/ 6.99 s compared to Propofol 19.4/ 7.51 s & Thiopentone 24/ 6.99 s. Though significant rise in HR, SBP, DBP and MAP was observed in all 3groups following ECT; but the rise was least in Propofol group. Significantly faster recovery was observed with Propofol. Immediate side effects were not significant in the three groups. Conclusion:Propofol seems to be superior to Etomidate and Sodium Thiopentone when used as an induction agent for modified ECT.

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Section: Resultsmentioning

confidence: 55%