Comparison of erythromycin and oxytetracycline for the treatment of ovine footrot

Abstract

A microbiological study of 25 cases of ovine footrot was performed. Cultures belonging to Dichelobacter nodosus were isolated in 48% of the sampled animals. The sensitivity of the 99 strict anaerobic bacterial isolates to 5 antibiotics (penicillin G, amoxycillin, spiramycin, erythromycin and oxytetracycline) was studied. The percentage of resistant cultures was in all cases higher than 30%. The efficacy of erythromycin and oxytetracycline in the treatment of ovine footrot was studied. To conduct this test, an intramuscular injection was applied, of one antimicrobial or the other, at the beginning of the treatment. The tolerance of animals to the antimicrobials, the success rate of treatment and the severity of lameness were evaluated. The percentage of animals cured within 15 days was around 75%. In contrast, only 44% improvement was achieved in the lameness. No differences were found between the two antimicrobials in the above indices.

In vitro antimicrobial susceptibility of anaerobic bacteria isolated from caprine footrot

“…Jiménez (2001) found doxycycline to be the most efficacious member of the family, followed by tetracycline and lastly oxytetracycline (which elicited 81.9% resistance among Bacteroides). In the same year Píriz et al (2001) found 37% resistance in Bacteroides strains isolated from 25 cases of ovine footrot.…”

Man-tailored biomimetic sensor of molecularly imprinted materials for the potentiometric measurement of oxytetracycline

“…Analytical procedures suggested in the literature for OXY detection and quantification regard microbiological methods (Jevinova et al, 2003;Gesche et al, 2001;Piriz et al, 2001;Myllyniemi et al, 2000;Okerman et al, 2001;Tantillo et al, 1997;Markakis, 1996;Wanner et al, 1994;Hasselberger, 1993;Jinbo et al, 1992;Roudaut et al, 1987;Muellerbrennecke et al, 1980) or liquid-chromatographic techniques (Khosrokhavar et al, 2008;Fletouris and Papapanagiotou, 2008;Maia et al, 2008;Kowalski and Pomorska, 2007;Biswas et al, 2007;Fritz and Zuo, 2007;Miller et al, 2007;Kowalski et al, 2006;Hosseini et al, 2006;Poapolathep et al, 2008;Yegorova et al, 2006;Pena et al, 2005;Rupp and Anderson, 2005;Lu et al, 2004;Schneider et al, 2007;Kim et al, 2006). The former is unsuitable for routine control procedures considering that each trial may take several days, and analytical laboratories also require proper facilities to handle biological compounds safely.…”

Effectiveness of different adjuvants in stimulating Dichelobacter nodosus antibody in sheep vaccinated against ovine footrot

“…This syndrome is responsible for major economic losses to the sheep production sector in Spain, an about 10% decrease in mutton and wool production and a 20% decrease in milk production (Píriz et al, 2001). It consists of exudative swelling followed by ischaemia and subsequent necrosis of the epidermal tissues of the claw, leading to complete separation of the horn (Colson, 1974;Fredet, 1974;Baber, 1979;Katitch, 1983;Brugère-Picoux, 1987).…”