Comparison of Epidural Fentanyl Versus Epidural Sufentanil for Analgesia in Ambulatory Patients in Early Labor

Analgesia controlada pelo paciente com fentanil e sufentanil no pós-operatório de reconstrução de ligamentos do joelho: estudo comparativo

“…Além do mais, as doses de infusão contínua e em bolus foram menores do que aquelas administradas por outros autores 8, [15][16][17] . O sufentanil também tem sido empregado em ACP mostrando bons resultados no controle da dor pós-operatória 18,19 . O objetivo deste estudo foi comparar o fentanil e o sufentanil em analgesia controlada pelo paciente, por via peridural, com bomba de infusão contínua, em pacientes submetidos a cirurgias para reconstrução de ligamentos de joelho.…”

“…Moreover, continuous infusion and bolus doses were lower than those administered by other authors 8, [15][16][17] . Sufentanil has also been used in PCA with good results in controlling postoperative pain 18,19 . The aim of this study was to compare fentanyl and sufentanil in patient-controlled epidural analgesia with continuous infusion pump, in patients submitted to knee ligament reconstruction.…”

The addition of hydromorphone to epidural fentanyl does not affect analgesia in early labour

“…We have successfully utilized epidural opioids following a lidocaine-epinephrine test dose to provide satisfactory analgesia without a significant motor block. [1][2][3][4][5][6] The current study compared 100 µg of fentanyl after a lidocaine and epinephrine test dose in primigravid patients with and without concomitant hydromorphone (300 µg). The goal of the hydromorphone was to prolong the duration of analgesia.…”

“…E previously showed that epidural fentanyl or sufentanil, after a lidocaine-epinephrine test dose, provides approximately two hours of analgesia, while allowing patients to ambulate. [1][2][3][4][5][6] Fentanyl is the most commonly chosen opioid at our institution for early labour ambulatory epidurals based on its low cost and the fact there was a lack of significant analgesic difference compared to sufentanil. 3 In a pilot study, hydromorphone 300 µg following a lidocaine-epinephrine test dose demonstrated an analgesic onset time of greater than 20 min, which was determined to be too long to be clinically useful.…”

“…[1][2][3][4][5][6] Fentanyl is the most commonly chosen opioid at our institution for early labour ambulatory epidurals based on its low cost and the fact there was a lack of significant analgesic difference compared to sufentanil. 3 In a pilot study, hydromorphone 300 µg following a lidocaine-epinephrine test dose demonstrated an analgesic onset time of greater than 20 min, which was determined to be too long to be clinically useful. We postulated that combining a "quick-onset" short-acting opioid (i.e., fentanyl) with a longer-onset, longeracting opioid (i.e., hydromorphone) would achieve the benefits of both medications: a quick-onset, long duration "ambulatory" epidural.…”