Comparison of Endobronchial Ultrasound and/or Endoesophageal Ultrasound with Transcervical Extended Mediastinal Lymphadenectomy for Staging and Restaging of Non–Small-Cell Lung Cancer

Zieliński, Marcin; Szlubowski, Artur; Kołodziej, Marcin; Orzechowski, Stanisław; Laczyńska, E; Pankowski, Juliusz; Jakubiak, Magdalena; Obrochta, Anna

doi:10.1097/jto.0b013e318287c0ce

Cited by 59 publications

(39 citation statements)

References 17 publications

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“…In the restaging group, endoscopic staging was performed in 88 patients and TEMLA in 78 patients. There was a significant difference between EBUS or EUS and TEMLA for sensitivity (64.3% and 100%; p<0.01) and NPV (82.1% and 100%; p<0.01) in favour of TEMLA [92].…”

Section: Diagnosis For Mediastinal Nodes (N-status)mentioning

confidence: 93%

Staging of lung cancer: the role of noninvasive, minimally invasive and invasive techniques

Stamatis

2015

Eur Respir J

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Accurate staging and restaging of primary tumour and mediastinal nodes in patients with lung cancer is of significant importance. For primary tumours, computed tomography (CT) scans of the chest are recommended. Positron emission tomography (PET) imaging should be used in patients with curative intent treatment to evaluate metastatic disease. Diagnosis of the primary tumour should be performed using bronchoscopy or CT-guided transthoracic needle aspiration. In patients with enlarged mediastinal nodes and no distant metastasis, invasive staging of the mediastinum is required. For suspicious N2 or N3 disease, endoscopic needle techniques, such as endobronchial ultrasound and transbronchial needle aspiration, oesophageal ultrasound and fine needle aspiration, or a combination of both, are preferred to any surgical staging technique. In cases of suspicious nodes and negative results using needle aspiration techniques, invasive surgical staging using mediastinoscopy or video-assisted thoracic surgery should be performed. In central tumours or N1 nodes, preoperative invasive staging is indicated.Restaging after induction therapy remains a controversial topic. Today, neither CT, PET nor PET/CT scans are accurate enough to make final further therapeutic decisions for mediastinal nodal involvement. An invasive technique providing cytohistological information is still recommended.

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Section: Diagnosis For Mediastinal Nodes (N-status)mentioning

confidence: 93%

Staging of lung cancer: the role of noninvasive, minimally invasive and invasive techniques

Stamatis

2015

Eur Respir J

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“…Significant differences were found between EBUS or EUS and TEMLA for sensitivity (64.3% and 100%; p<0.01) and negative predictive value (82.1% and 100%; p<0.01), in favour of TEMLA [59].…”

Section: Review Of the Studies Eus Studiesmentioning

confidence: 91%

Combined endobronchial and oesophageal endosonography for the diagnosis and staging of lung cancer

et al. 2015

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“…[45] Ancak, TEMLA, yeniden evrelemede şu ana kadar en iyi sonuçları, başka bir deyişle, gerçek patolojik lenf nodu tutulumunu ameliyat öncesinde gösteren en iyi 'tekrar evreleme' yöntemidir. [46] Bu yöntem ile, tekrar evrelenen hastalarda negatif öngördürücü değer %99, hassasiyet %97 ve özgüllük %100 olarak bulunmuştur. [47] -Yedinci evrelemede kullanılan N tanımlayıcı özellikleri değişiklik olmaksızın sekizinci evrelemeye taşınmıştır.…”

Section: İndüksi̇yon Tedavi̇si̇ Sonrasinda Medi̇asti̇nal Evrelemeunclassified

The eighth staging system of non-small cell lung cancer and its practical implications

Turna¹

2017

Turk Gogus Kalp Dama

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ÖZEvreleme akciğer kanserli hastalara yaklaşımın önemli bir kısmını oluşturmaktadır. Tümör sınıflandırmasının esas amacı hastalığın anatomik yaygınlığını doğru olarak ortaya koymaktır. Tümörün anatomik yaygınlığı tedavi seçimi ve prognoz üzerinde önemli bir etkiye sahiptir. Küçük hücreli dışı akciğer kanserinde hastalara genel yaklaşım; mediastenin evrelenmesi ve toraks dışı evreleme için evreleme yöntemlerini, öykü ve fizik muayene, görüntüleme, minimal invaziv teknikler ve invaziv cerrahi teknikleri içermektedir. Mevcut akciğer kanseri evreleme sistemi tümör, lenf nodu ve metastaz (TNM) sınıflamasının Ocak 2017'de kullanılmaya başlanan sekizinci baskısıdır. Bu makalede, küçük hücreli dışı akciğer kanserinde evreleme yöntemleri ile birlikte mevcut TNM tanımlayıcıları ve evre grupları için tanımlar gözden geçirildi. Değişen T, N ve M tanımlayıcılarının hastalarda tedavi seçeneklerini daha iyi işaret edebildiği ve sağkalımı daha doğru bir şekilde öngörebildiği görülmektedir.Anah tar söz cük ler: Sekizinci evreleme sistemi; akciğer kanseri; M faktörü; N faktörü; T faktörü. ABSTRACTStaging is an essential part of the approach to patients with lung cancer. The primary goal of the tumor classification is to correctly describe the anatomic extent of the disease. The anatomic extent of the tumor has a major impact on the treatment selection and prognosis. The general approach to patients with non-small cell lung cancer include mediastinal staging and non-thoracic staging methods, history and physical examination, imaging, minimally invasive techniques, and invasive surgical techniques. The current lung cancer staging system is the eighth edition of the tumor, node, and metastasis (TNM) classification, which was took effect in January 2017. In this article, staging methods and the definitions for current T, N, M descriptors and the stage groups in non-small cell lung cancer are reviewed. New definitions of T, N, and M factors seem to better indicate the most optimal treatment option for an individual patient and to better predict the survival in patients.

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Comparison of Endobronchial Ultrasound and/or Endoesophageal Ultrasound with Transcervical Extended Mediastinal Lymphadenectomy for Staging and Restaging of Non–Small-Cell Lung Cancer

Abstract: The results of this largest reported series comparing the endoscopic and surgical primary staging and restaging of NSCLC showed a significantly higher diagnostic yield of TEMLA when compared with that of EBUS or EUS.

Cited by 59 publications

References 17 publications

Staging of lung cancer: the role of noninvasive, minimally invasive and invasive techniques

Staging of lung cancer: the role of noninvasive, minimally invasive and invasive techniques

Combined endobronchial and oesophageal endosonography for the diagnosis and staging of lung cancer

The eighth staging system of non-small cell lung cancer and its practical implications

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