Comparison of Electron Beam Computed Tomography With Magnetic Resonance Imaging in Assessment of Right Ventricular Volumes and Function

Elgeti, Thomas; Lembcke, Alexander; Enzweiler, Christian N.H.; Breitwieser, Christoph; Hamm, Bernd; Kivelitz, Dietmar

doi:10.1097/01.rct.0000134197.12043.a6

Cited by 14 publications

(5 citation statements)

References 37 publications

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“…Precise flow measurements in the heart and great vessels can be made using velocity-encoded imaging. Interobserver variability is low, which makes magnetic resonance imaging a potential tool for follow-up assessment (168,169). The SERAPH (Sildenafil versus Endothelin Receptor Antagonist for Pulmonary Hypertension) study used CMR to compare the effect of bosentan and sildenafil on RV hypertrophy (170).…”

Section: Invasive Hemodynamicsmentioning

confidence: 99%

Diagnosis and Assessment of Pulmonary Arterial Hypertension

Badesch

Champion

Sánchez

et al. 2009

Journal of the American College of Cardiology

1,017

735

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The diagnosis and assessment of pulmonary arterial hypertension is a rapidly evolving area, with changes occurring in the definition of the disease, screening and diagnostic techniques, and staging and follow-up assessment. The definition of pulmonary hypertension has been simplified, and is now based on currently available evidence. There has been substantial progress in advancing the imaging techniques and biomarkers used to screen patients for the disease and to follow up their response to therapy. The importance of accurate assessment of right ventricular function in following up the clinical course and response to therapy is more fully appreciated. As new therapies are developed for pulmonary arterial hypertension, screening, prompt diagnosis, and accurate assessment of disease severity become increasingly important. A clear definition of pulmonary hypertension and the development of a rational approach to diagnostic assessment and follow-up using both conventional and new tools will be essential to deriving maximal benefit from our expanding therapeutic armamentarium.

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Section: Invasive Hemodynamicsmentioning

confidence: 99%

Diagnosis and Assessment of Pulmonary Arterial Hypertension

Badesch

Champion

Sánchez

et al. 2009

Journal of the American College of Cardiology

1,017

735

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“…Furthermore, the variability of temporal resolution according to the HR profoundly limits the reliable evaluation of LV function. A temporal resolution of 30-50 ms is required for precise evaluations of LV function [23]. The optimal number of reconstruction phases is dependent on the temporal resolution of the CT scanner and HR (Table 4).…”

Section: Discussionmentioning

confidence: 99%

Comparison of global left ventricular function using 20 phases with 10-phase reconstructions in multidetector-row computed tomography

Kim

Park

et al. 2011

Int J Cardiovasc Imaging

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To compare the measurement of global left-ventricular (LV) function parameters of 64-slice multidetector-row computed tomography (MDCT) between 20- and 10-reconstruction phases. Fifty five patients with suspected or known coronary artery disease underwent 64-slice MDCT. LV end-diastolic volume (EDV), end-systolic volume (ESV), stroke volume (SV), and ejection fraction (EF) were measured from MDCT data sets using threshold-based volume segmentation and reconstruction at every 5% (20 phases) and 10% (10 phases) step through the R-R interval. These global functional parameters were compared to those obtained via two-dimensional transthoracic echocardiography (2D-TTE), considering the reference standard. The required time for CT data analysis was checked. Agreement for parameters of LV global function was determined using Pearson's correlation coefficient (r) and Bland-Altman analysis. LV volumes (EDV(-5%) 87.5 ± 17.1 ml, EDV(-10%) 87.7 ± 16.3 ml; ESV(-5%) 32.4 ± 10.6 ml, ESV(-10%) 31.9 ± 9.9 ml; SV(-5%) 55.1 ± 10.5 ml, SV(-10%) 55.8 ± 9.9 ml; mean ± SD) and EF (EF(-5%) 63.4 ± 6.2%, EF(-10%) 63.9 ± 5.8%) did not differ significantly between the 20- and 10 phase reconstructions, and evidenced good to excellent correlation (r = 0.786-0.896, all P < 0.001) with the 2D-TTE results. The mean required time for CT data analysis in the 20- and 10 phase reconstructions were 15.5 ± 4.0 and 7.3 ± 2.5 min. Within MDCT, using 10-phase image reconstruction is sufficient to evaluate LV volumes and EF, and is also more time-effective than 20-phase reconstruction.

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“…Wie die MRT erlaubt auch die CT nicht nur eine Beurteilung des linken, sondern auch des rechten Ventrikels [3,19,20], welcher sowohl primär betroffen oder aber sekundär in die Erkrankung einbezogen werden kann. Dabei ist zudem darauf zu verweisen, dass rechtsventrikuläre Funktionsparameter unabhängige Prä-diktoren des Krankheitsverlaufs sowohl bei idiopathischer als auch ischämischer Kardiomyopathie sind [21,22].…”

Section: Einführungunclassified

Chirurgie der Herzinsuffizienz - Stellenwert der Computertomographie in der prä- und postoperativen Diagnostik

Lembcke¹,

Dohmen²,

Wiese³

et al. 2005

Rofo Fortschr Geb Rontgenstr N

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The treatment of advanced, drug resistant congestive heart failure gains in importance in the field of cardiac surgery. Cardiac imaging for preoperative assessment and follow-up focuses on the determination of ventricular volumes and function as well as on the detection of postoperative complications. Computed tomography (CT) is highly accurate irrespective of the individual patient's anatomic situation, has a low examiner dependence and short examination time, does not require an arterial vascular access and can be performed in patients with metal implants. CT is the modality of choice in the follow-up of heart transplants to detect extracardiac and cardiac complications including coronary calcifications as an early sign of transplant vasculopathy. In addition, CT visualizes the elements of mechanical assist devices and can identify their possible local cardiac and mediastinal complications. CT can detect fibrolipomatous involution of the mobilized muscle flap in dynamic cardiomyoplasty and can depict fibrous reactions along the epicardial mesh implant in passive cardiac containment. Further indications include assessment of typical local postoperative complications, such as intrathoracic infection and mediastinal bleeding, intracardiac thrombus formation or pericardial effusion. CT is routinely used for evaluating bypass patency but is limited in assessing associated valve defects since it does not visualize flow.

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Comparison of Electron Beam Computed Tomography With Magnetic Resonance Imaging in Assessment of Right Ventricular Volumes and Function

Abstract: Electron beam computed tomography shows good agreement with a close correlation and an acceptable interobserver variability for right ventricular volumes and global function, with a small but significant overestimation of EDV and ESV when compared with MRI.

Cited by 14 publications

References 37 publications

Diagnosis and Assessment of Pulmonary Arterial Hypertension

Diagnosis and Assessment of Pulmonary Arterial Hypertension

Comparison of global left ventricular function using 20 phases with 10-phase reconstructions in multidetector-row computed tomography

Chirurgie der Herzinsuffizienz - Stellenwert der Computertomographie in der prä- und postoperativen Diagnostik

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