Comparison of effects of six main gastrectomy procedures on patients’ quality of life assessed by Postgastrectomy Syndrome Assessment Scale-45

Nakada, Koji; Kawashima, Yasunaru; Kinami, Shinichi; Yabusaki, Hiroshi; Seshimo, Akiyoshi; Hiki, Naoki; Koeda, Keisuke; Kano, Mikihiro; Uenosono, Yoshikazu; Oshio, Atsushi; Kodera, Yasuhiro

doi:10.4240/wjgs.v13.i5.461

Cited by 14 publications

(18 citation statements)

References 44 publications

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“…In recent years, the PGSAS-37 has been developed by the Japan Postgastrectomy Syndrome Working Party to establish an adequate instrument to assess the symptoms, living status, and QOL of postgastrectomy patients [10,12]. Using this questionnaire, several nationwide multi-institutional collaborative studies have been conducted to elucidate the effects of gastrectomy procedures on the daily living of gastrectomized patients [11][12][13][26][27][28]. Nakada et al demonstrated that total gastrectomy with Roux-en-Y reconstruction and proximal gastrectomy among the six main gastrectomy procedures signi cantly impaired the QOL of postoperative patients [13].…”

Section: Discussionmentioning

confidence: 99%

“…Using this questionnaire, several nationwide multi-institutional collaborative studies have been conducted to elucidate the effects of gastrectomy procedures on the daily living of gastrectomized patients [11][12][13][26][27][28]. Nakada et al demonstrated that total gastrectomy with Roux-en-Y reconstruction and proximal gastrectomy among the six main gastrectomy procedures signi cantly impaired the QOL of postoperative patients [13]. Therefore, it is essential to evaluate the function of the esophagogastric anastomosis and the QOL in patients who have undergone proximal gastrectomy, such as the one described in this paper.…”

Section: Discussionmentioning

confidence: 99%

“…While clinical outcomes in patients undergoing proximal gastrectomy with the hinged double ap method have been well assessed, the anti-re ux mechanism in terms of intraesophageal pressure remains unproven. This study objectively assessed the function of esophagogastric anastomosis in patients who underwent proximal gastrectomy with the hinged double ap and validated the usefulness of high-resolution impedance manometry (HRIM) after proximal gastrectomy with the hinged double ap method by applying the Postgastrectomy Syndrome Assessment Scale-37 (PGSAS-37) to assess patient status [10][11][12][13].…”

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

Intraesophageal Pressure in Patients Receiving Proximal Gastrectomy with Hinged Double Flap Method for Gastric Cancer

Saeki

Tanabe

Chikuie

et al. 2023

Preprint

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Background Objective functional assessment of esophagogastric anastomosis in patients who underwent proximal gastrectomy with the hinged double flap method for gastric cancer has not been well investigated. This study aimed to perform a functional analysis of reconstruction using high-resolution impedance manometry (HRIM). Methods The subjects comprised 25 patients receiving proximal gastrectomy for gastric cancer between May 2015 and April 2020. Eligible questionnaires (Postgastrectomy Syndrome Assessment Scale − 37 [PGSAS-37]) were retrieved from 16 patients. The data of this study were compared with the values of the Japanese standard data from the PGSAS study. Results The quality of ingestion subscale had a significant influence on patients’ weight loss and weight loss rate one year after surgery (r = -0.874, p = 0.0048, r = -0.876, p = 0.0044, respectively). The amplitudes of distal esophageal peristaltic waves, contractile front velocity, and distal latency assessed by HRIM were almost normal after surgery. Most patients showed lower esophageal sphincter (LES) resting pressure within normal limits, whereas all patients showed abnormal LES residual pressure during swallowing-induced relaxation. However, high LES residual pressure during swallowing-induced relaxation did not attribute to deterioration the patients’ quality of life; the results of the PGSAS-37 score in this study were comparable to the values of patients who underwent proximal gastrectomy in Japan. Conclusions Proximal gastrectomy impaired swallowing-induced relaxation of LES. On the other hand, LES resting pressure created by the hinged double flap was maintained after surgery, and the postoperative outcome was good.

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Intraesophageal Pressure in Patients Receiving Proximal Gastrectomy with Hinged Double Flap Method for Gastric Cancer

Saeki

Tanabe

Chikuie

et al. 2023

Preprint

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“…In addition, this study enrolled patients with early gastric cancer of Stage IA/IB/IIA (T3, N0) to exclude the influence of postoperative chemotherapy. Furthermore, since we felt that a comparison between only B1 and RY reconstruction might be insufficient, TG reconstruction, which usually results in the poorest QOL, was used as a control group [ 19 , 20 ]. The study results showed that the BWR in the L-B1 group was significantly higher than in the L-RY and L-TG groups.…”

Section: Discussionmentioning

confidence: 99%

Functional evaluations comparing Billroth I with a large remnant stomach and Roux en Y with a small remnant stomach following laparoscopic distal gastrectomy for gastric cancer: An investigation including laparoscopic total gastrectomy

et al. 2022

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Purpose This study compared the pros and cons of two post-distal gastrectomy (DG) reconstruction methods by comparing the patient quality of life and functional dynamics at one year postoperatively. Methods We compared functional outcomes between Billroth I following laparoscopic 1/2 DG (L-B1; n = 27) and Roux en Y following laparoscopic 4/5 DG (L-RY; n = 24), including laparoscopic total gastrectomy (L-TG; n = 25), at one year postoperatively. Clinical investigations were performed in each patient, and functional evaluations by the acetaminophen (AAP) absorption test and plasma gastrointestinal hormone measurements were performed in consenting patients in each group (L-B1: n = 10, L-RY: n = 10, L-TG: n = 5). Results Postoperative/preoperative body weight ratios were significantly higher in the L-B1 and L-RY groups, in descending order than the L-TG group, although the meal intake ratio was not significantly different between the L-B1 and L-RY groups. The incidence of remnant gastritis was significantly higher in the B1 than in the RY group. AAP levels, glucose and glucagon-like peptide 1 were significantly lower in the L-B1 than in the L-RY group. Active ghrelin levels (AGL) were similar between the L-B1 and L-RY groups. Conclusions L-B1 maintains gradual intestinal absorption and physiological meal passage and prevents postoperative weight loss. L-RY results in maintenance of the postoperative meal intake via high AGL, equivalent to that in the L-B1 group.

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“…Proximal gastrectomy is a frequent procedure in Japan and Korea due to the high incidence of early gastric cancer. There are several reconstruction techniques to reduce pathological acid or bile reflux since several physiological anti-reflux mechanisms are eliminated after a proximal gastrectomy [10] [11]. However, they are complex techniques, such as the "Kamikawa" reconstruction, that increase the surgical time and the risk of late stenosis [12] [13].…”

Section: Introductionmentioning

confidence: 99%

Esophagogastric Reconstruction in Cobra-Head Shape with Toupet-Like Partial Anti-Reflux Technique for Resection of Proximal Gastric Tumors. Experience with Three Cases from a Non-Asian Population

León-Takahashi¹,

Meléndez-Fernández²,

Lino‐Silva³

et al. 2023

OJGas

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Background: Proximal gastrectomy is a rarely performed procedure but a feasible option in benign tumors and malignant neoplasms in the proximal third of the stomach since novel options of reconstructions are available nowadays with fewer long-term sequels. Methods: Report of three cases of proximal gastric gastrointestinal stromal tumors (GIST), with a description of its presentation, histological characteristics, and follow-up after being treated with proximal gastrectomy with cobra head reconstruction. Results: Case 1: A 62-year-old woman with epigastric pain of four months with endoscopic evidence of a cardia GIST. The surgery was performed without complications. The histopathological report confirmed a fusiform GIST of 3.2 × 3 × 2.5 cm, stage IA. No adjuvant treatment was considered. An esophagogram showed no evidence of reflux and no stenosis, and no disease recurrence after 40-months follow-up. Case 2: A 66-year-old woman with dyspepsia and a palpable tumor in the epigastrium. The surgery was performed without complications. The pathology report confirmed a proximal gastric GIST of 13 × 8 × 7 cm, staged II. She received adjuvant treatment with imatinib for 36 months without recurrence and no reflux or stenosis. Case 3: A 55-year-old woman with intermittent hematemesis and right subscapular pain. The surgery was performed without complications.

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Comparison of effects of six main gastrectomy procedures on patients’ quality of life assessed by Postgastrectomy Syndrome Assessment Scale-45

Cited by 14 publications

References 44 publications

Intraesophageal Pressure in Patients Receiving Proximal Gastrectomy with Hinged Double Flap Method for Gastric Cancer

Intraesophageal Pressure in Patients Receiving Proximal Gastrectomy with Hinged Double Flap Method for Gastric Cancer

Functional evaluations comparing Billroth I with a large remnant stomach and Roux en Y with a small remnant stomach following laparoscopic distal gastrectomy for gastric cancer: An investigation including laparoscopic total gastrectomy

Esophagogastric Reconstruction in Cobra-Head Shape with Toupet-Like Partial Anti-Reflux Technique for Resection of Proximal Gastric Tumors. Experience with Three Cases from a Non-Asian Population

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