Comparison of Different Strategies to Use Four-Dimensional Computed Tomography in Treatment Planning for Lung Cancer Patients

Wolthaus, J.; Sonke, Jan‐Jakob; Herk, Marcel van; Belderbos, J.; Rossi, Maddalena; Lebesque, Joos V.; Damen, E.

doi:10.1016/j.ijrobp.2007.11.042

Cited by 261 publications

(235 citation statements)

References 31 publications

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“…mid-ventilation (Wolthaus et al, 2008) the size of the tumor and subsequently the size of the PTV can be deduced. From the full inhale and full exhale phases from the other hand the range of motion can be estimated, In addition to the look-up curves analytic fits to the data presented on Figure 5 were performed.…”

Section: Discussionmentioning

confidence: 99%

Relation Between Tumor Size and Range of Motion in IMRT Treatment Planning for Thoracic Lesions

Mihaylov

Lerma

Moros

2010

JCST

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Section: Discussionmentioning

confidence: 99%

Relation Between Tumor Size and Range of Motion in IMRT Treatment Planning for Thoracic Lesions

Mihaylov

Lerma

Moros

2010

JCST

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“…These spheres were chosen as the most relevant considering the typical size of lung tumours treated. Wolthaus et al [15] reported GTV volumes between 2 and 200 cm 3 corresponding to tumour diameters between 1.5 and 7.2 cm in their study of 45 patients with non-small-cell lung cancer.…”

Section: Phantommentioning

confidence: 96%

The potential for undertaking slow CT using a modern CT scanner

Chinneck

McJury²,

Hounsell³

2010

BJR

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ABSTRACT. Respiratory motion complicates target volume definition for patients with lung cancer. The use of slow CT to aid in the definition of moving target volumes was investigated. Standard and slow scans of an oscillating phantom were acquired using gantry rotation periods of 0.8 and 1.5 s and pitches of 0.95 and 0.50, respectively. The resultant images of three spheres within the phantom, labelled as A, B and C with diameters of 3.7, 2.8 and 2.2 cm, were analysed. The central co-ordinates of each volume were determined, and the ratio of the target volume outlined on CT (TV CT ) to the true target volume (TV) was calculated. For 1.5 cm peak-to-trough (PTT) motion, standard CT mean ratios of 0.8, 0.8 and 0.7 were obtained for spheres A, B and C, respectively, whereas slow CT resulted in a mean ratio of 0.9 for all three spheres. For 2.5 cm motion, standard CT mean ratios of 0.8, 0.7 and 0.7 were obtained, whereas the slow CT mean ratios were 0.9, 0.9 and 0.8. The deviation of the central co-ordinate for the slow CT volumes was within 0.1 cm whereas deviations of up to 0.7 cm were seen using standard CT. This study indicates the potential benefit of using slow CT, even on modern scanners capable of rotation periods only down to 1.5 s, to define moving target volumes more accurately and reproducibly moving target volumes, and aid in the management of respiratory motion for patients with lung cancer.

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“…The MidP strategy presents several advantages (31). First, as the MidP image corresponds to an averaged image from all transformed frames, it is less noisy (better signalto-noise ratio) than each separate time frame.…”

Section: In Room Imaging and Positioningmentioning

confidence: 99%

“…More importantly, the MidP eliminates the systematic error due to 3D sampling or tumor hysteresis. Inmargin-based approaches, which are more suitable for tomotherapy treatment, aim at either covering the entire tumor trajectory derived from 4D information (internal target volume, ITV) (30), or at taking advantage of the geometrical time-weighted mean tumor position (MidPosition, MidP) (31).…”

Section: In Room Imaging and Positioningmentioning

confidence: 99%

4D PET-CT guided radiation therapy

Geets¹

2013

Journal of the Belgian Society of Radiology

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Comparison of Different Strategies to Use Four-Dimensional Computed Tomography in Treatment Planning for Lung Cancer Patients

Cited by 261 publications

References 31 publications

Relation Between Tumor Size and Range of Motion in IMRT Treatment Planning for Thoracic Lesions

Relation Between Tumor Size and Range of Motion in IMRT Treatment Planning for Thoracic Lesions

The potential for undertaking slow CT using a modern CT scanner

4D PET-CT guided radiation therapy

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