2001
DOI: 10.1016/s0304-8853(00)01248-8
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Comparison of different particles and methods for magnetic isolation of circulating tumor cells

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Cited by 103 publications
(54 citation statements)
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“…Surface modification of the radiolabeled ferrite may be obtained by adjusting the pH value in the aqueous reaction solution or by adding reducing reagents. As in previous reports [90][91][92][93], this study also demonstrated the immune response toward the intravenously injected particles, which were recognized as foreign and were removed from blood circulation by the mononuclear phagocytic system (MPS).…”
Section: Passive Targeting Radiolabeled Nanoparticlessupporting
confidence: 80%
“…Surface modification of the radiolabeled ferrite may be obtained by adjusting the pH value in the aqueous reaction solution or by adding reducing reagents. As in previous reports [90][91][92][93], this study also demonstrated the immune response toward the intravenously injected particles, which were recognized as foreign and were removed from blood circulation by the mononuclear phagocytic system (MPS).…”
Section: Passive Targeting Radiolabeled Nanoparticlessupporting
confidence: 80%
“…In particular, more sophisticated ways of particle application, e.g. magnetic field gradient targeting [4] or coupling of magnetic nanoparticles via specific tumour binding antibodies [5], would become realistic. The temperature increase in the tumour region enriched with magnetic particles is controlled by the two concurrent processes of heat generation in the particles and heat distribution into the neighboured tissue mainly by heat conduction [6].…”
Section: Introductionmentioning
confidence: 99%
“…In order to overcome these limitations, magnetic nanoparticles are usually used in the forms of composites. Existing magnetic composites usually have two types [5][6][7][8]: (1) core-shell structures that consist of a superparamagnetic nanoparticle core and a variety of shells, such as silica, [9] oleic acid, [10] polystyrene [11], etc. (most of these magnetic composites are very dense); (2) special matrixes that contain dispersed superparamagnetic particles, such as mesoporous silica, [12,13] starch and methoxypoly (ethylene glycol) [10].…”
mentioning
confidence: 99%